Sochaux return to the scene of last season's great escape as they visit Bastia in dire need of a win to boost hopes of Ligue 1 safety.
The Stade Auguste Bonal club claimed a 0-0 draw on the final day of last term in Corsica, which proved enough to ensure survival as Nancy, Troyes and Brest fell into the second tier.
Herve Renard's men will be desperate to go one better at the Stade Armand Cesari this time around.
A last-minute equaliser denied Sochaux a crucial victory over Marseille last weekend and the strugglers head into the weekend eight points adrift of 17th-placed Evian.
Valenciennes are three points above Sochaux and host a Lyon side still harbouring slim hopes of qualifying for the UEFA Champions League and keen to atone for a 2-1 derby loss to Saint-Etienne.
Evian's stunning 1-0 win over second-placed Monaco last time out significantly enhanced their prospects of remaining in the top flight.
And Pascal Dupraz's men could take another step towards safety with a victory at Lorient, who are not yet sure of their place in Ligue 1 for next term.
Six points could separate 11th and 18th by the end of the 32nd round of fixtures, but the picture at the top of the table is far clearer.
Paris Saint-Germain appear to have all but secured a second consecutive title and sit 13 points clear of Monaco.
The capital club can edge ever closer to glory by beating Reims, while Monaco will be aware they may yet come under pressure in the race for Champions League places.
Claudio Ranieri's men currently hold a nine-point advantage over fourth-placed Saint-Etienne and host a Nantes side unbeaten in four.
Saint-Etienne's immediate target is overhauling third-placed Lille, with only three points separating the two sides heading into the weekend.
Next up for Saint-Etienne is a home game against Nice, who narrowly missed out on a Champions League berth last season when finishing only three points behind Lyon.
Lille's trip to Toulouse pits two in-form teams against each other as Rene Girard's men look to make it nine league games unbeaten against a home side without a defeat in five.
Elsewhere, Bordeaux host Rennes, Guingamp meet Montpellier and bottom club Ajaccio travel to a Marseille side in the midst of a dreadful slump.
Jose Anigo's side took just two points from five games in March, a run that has left them nine points adrift of a European place and one that forward Andre Ayew attributes to Marseille's lack of experience.
"I think when you buy young players in a club like Marseille, with a lot of pressure, some players can cope with it no problem, and some others need time," Ayew told BeIN Sport.
"That's why there are a lot of ups and downs, and we need to be more consistent."
|Coach: F. Hantz|
for F. Raspentino 46'
for F. Harek 59'
for J. Sablé 87'
|Spartak donate money to 102-year-old fan after robbery|
|Clasie pulls out of Netherlands squad|
|Italy´s Bertolacci out of England friendly|
|Newcastle post record profit as Ashley debt stays the same|
|Al Sadd: We want Xavi to bring tiki-taka|
|Lacazette expected frosty Saint-Etienne reception|
|Barnes: I can´t get back into management because I´m black|
|Rooney praises England aggression|
|Southgate tips Kane for return to U21s|
|Mexico v Paraguay: Goals in order for Copa America aspirants|
|Peru v Venezuela: Sanvicente wants Venezuelan response|
|Carvalho confident of playing Juventus|
|Neymar demands protection after Medel stamp|
|MLS Review: RSL, Fire secure breakthrough wins|
|Firmino firmly on radar - Dunga|
|O´Neill delighted with second-half display|
|First-half dominance pleases Deschamps|
|Muller criticises Germany profligacy|
|Euro 2016 Qualifying Review: Portugal go top, Gibraltar make history in defeat|
|Liverpool the only English club I could play for - Suarez|
|France 2 Denmark 0: Lacazette off the mark in routine victory|
|Republic of Ireland 1 Poland 1: Long rescues vital point|
|Portugal 2 Serbia 1: Coentrao puts hosts top of Group I|
|Strachan hails ´terrific´ Gibraltar|
|Lafferty back playing with a smile on his face - O´Neill|
|Toure to reveal Ivory Coast future over coming days|
|Georgia 0 Germany 2: Reus and Muller on target for world champions|
|Northern Ireland 2 Finland 1: Lafferty inspires fourth qualifying success|
|Scotland 6 Gibraltar 1: Casciaro´s historic moment outshone by Fletcher´s hat-trick|
|France 2-0 Denmark: Lacazette and Giroud on target|
|Firmino hopeful of Copa America spot|
|Hummels considering options at Dortmund|
|Suarez goalless on Anfield return, but Balotelli nets stunner|
|Casciaro scores first competitive goal for Gibraltar|
|Fleetwood Town 1 Preston North End 1: Ball stunner claims share of derby spoils|
|Italy v England: Judge me on results, says Conte|
|Colombia v Kuwait: Falcao seeking another strong showing|
|Brazil 1 Chile 0: Firmino settles scrappy affair|
|Luxembourg v Turkey: Let´s kick on, urges Terim|
|South Africa 1 Nigeria 1: Zungu strikes late to earn draw|
|Smalling wants long-term United stay|
|South Africa 1-1 Nigeria: Last-gasp Zungu goal cancels out Musa strike|
|Italy call up Santon and Abate for England friendly|
|Switzerland v United States: Klinsmann eyes learning curve|
|Netherlands v Spain: Hiddink has players´ support, says Wijnaldum|
|A-League Review: Sydney end Wellington run, Adelaide suffer injury blows in Jets win|
|Henderson eyes long-term Liverpool future|
|I have nothing to prove - Bale|
|Brazil 1-0 Chile: Firmino gives Selecao battling victory|
|South Korea v New Zealand: All Whites looking to future|
|Japan v Uzbekistan: Hosts eye another win under Halilhodzic|
|MLS Review: Kaka nets in Orlando draw|
|Mexico 1 Ecuador 0: Hernandez, Corona help Herrera´s men to victory|
|Deschamps calls for France response|
|Dunga unfazed by pressure|
|Montenegro fan turns himself in after flare incident|
|Injured Messi not ready - Martino|
|Hodgson: Rooney not close to Charlton|
|Terim proud of Turkey|
|Hiddink happy with point|
|Euro 2016 Qualifying Review: Netherlands and Italy stage late escapes|
|Debutant Eder delighted with Azzurri bow|
|Argentina 2 El Salvador 0: Mancuello nets debut goal in straightforward win|
|Kovac not satisfied despite Croatia victory|
|Netherlands 1 Turkey 1: Huntelaar spares Hiddink from historic home loss|
|Ghana 1 Senegal 2: Konate brace downs Black Stars|
|Bulgaria 2 Italy 2: Controversial debutant Eder rescues Conte´s men|
|Morocco 0 Uruguay 1: Cavani spot-kick seals win|
|Al Sadd say talks with Xavi ongoing|
|McClean slams Sunderland´s handling of poppy controversy|
|Ghana 1-2 Senegal: Black Stars continue Afcon hangover|
|Cheltenham player diagnosed with cancer|
|Palace takeover talk premature - Parish|
|Odegaard becomes Euro qualifiers´ youngest starter|
|Job not done yet, Bale warns Wales|
|Israel 0 Wales 3: Brilliant Bale bags brace as Wales go top|
|Dunga backs Neymar to overhaul Pele´s Brazil goal record|
|League Two Review: Hartlepool climb out of drop zone, Cheltenham go bottom|
|El Salvador 0-2 Argentina: Martino's men triumph without Messi|
|League One Review: Canavan leaves it late to deny County|
|Freddy Adu signs with 11th team in as many years|
|Besiktas deny Cech, Danny rumours|
|Puerto Rico v Canada: Haber targets more momentum|
|Miranda not contemplating Atletico exit|
|Austin relaxed over England prospects|
|Manchester United should sign Ibrahimovic - Schmeichel|
|Ibe eyes Liverpool run-in|
|Bertrand called up by England as withdrawal of four players confirmed|
|A-League Review: Risdon nets stunner, Germano tames Roar|
|Panama v Costa Rica: Unbeaten run a secondary concern for Wanchope|
|Italy coach Conte shaken after death threats - FIGC chief|
|Barca fears over Alba eased|
|Schweinsteiger to start Germany qualifier|
|Akinfeev thanks fans after flare incident|
|Injuries offer Kane chance of first England start|
|Russian Football Union to protest following Montenegro abandonment|
|October comeback the target for injured Foster|
|Van der Vaart looks set to leave Hamburg|
|Bale focused on Wales - Coleman|
|Kluivert helps Curacao to victory|
|Hamstrung Alba returns to Barcelona|
|Macedonia v Australia: Confident visitors eye victory|
|Akinfeev to return to Moscow with Russia squad|
|Brnovic: Montenegro have no chance of qualifying|
|Russia had to resume after Akinfeev incident - Capello|
|Terim: Robben absence important|
|Brazil - Chile Preview: Winning is 'our only option' - Dunga|
|France - Denmark Preview: Olsen hits out at 'disrespectful' hosts|
|Morata keen to keep working|
|Canada 1 Guatemala 0: Haber heads Floro´s men to win|
|Difficult to find a place for Kane in starting XI - Hodgson|
|Difficult to find a place for Kane in starting XI - Hodgson|