Sochaux return to the scene of last season's great escape as they visit Bastia in dire need of a win to boost hopes of Ligue 1 safety.
The Stade Auguste Bonal club claimed a 0-0 draw on the final day of last term in Corsica, which proved enough to ensure survival as Nancy, Troyes and Brest fell into the second tier.
Herve Renard's men will be desperate to go one better at the Stade Armand Cesari this time around.
A last-minute equaliser denied Sochaux a crucial victory over Marseille last weekend and the strugglers head into the weekend eight points adrift of 17th-placed Evian.
Valenciennes are three points above Sochaux and host a Lyon side still harbouring slim hopes of qualifying for the UEFA Champions League and keen to atone for a 2-1 derby loss to Saint-Etienne.
Evian's stunning 1-0 win over second-placed Monaco last time out significantly enhanced their prospects of remaining in the top flight.
And Pascal Dupraz's men could take another step towards safety with a victory at Lorient, who are not yet sure of their place in Ligue 1 for next term.
Six points could separate 11th and 18th by the end of the 32nd round of fixtures, but the picture at the top of the table is far clearer.
Paris Saint-Germain appear to have all but secured a second consecutive title and sit 13 points clear of Monaco.
The capital club can edge ever closer to glory by beating Reims, while Monaco will be aware they may yet come under pressure in the race for Champions League places.
Claudio Ranieri's men currently hold a nine-point advantage over fourth-placed Saint-Etienne and host a Nantes side unbeaten in four.
Saint-Etienne's immediate target is overhauling third-placed Lille, with only three points separating the two sides heading into the weekend.
Next up for Saint-Etienne is a home game against Nice, who narrowly missed out on a Champions League berth last season when finishing only three points behind Lyon.
Lille's trip to Toulouse pits two in-form teams against each other as Rene Girard's men look to make it nine league games unbeaten against a home side without a defeat in five.
Elsewhere, Bordeaux host Rennes, Guingamp meet Montpellier and bottom club Ajaccio travel to a Marseille side in the midst of a dreadful slump.
Jose Anigo's side took just two points from five games in March, a run that has left them nine points adrift of a European place and one that forward Andre Ayew attributes to Marseille's lack of experience.
"I think when you buy young players in a club like Marseille, with a lot of pressure, some players can cope with it no problem, and some others need time," Ayew told BeIN Sport.
"That's why there are a lot of ups and downs, and we need to be more consistent."
|Coach: F. Hantz|
for F. Raspentino 46'
for F. Harek 59'
for J. Sablé 87'
|Van Basten to leave Netherlands´ backroom staff for FIFA role|
|Ventura perfect for Italy - Verratti|
|Martial needs to be more consistent - Deschamps|
|Verratti not happy at PSG - Ventura|
|Ventura: I´ll probably manage Chelsea when Conte leaves|
|Bartomeu: Barca discussing new contract with Messi|
|Bauza: No doubts over Messi motivation|
|Schmeichel targets quick return after surgery|
|Giovinco to help aid earthquake victims in Italy|
|Ancelotti backs Madrid for LaLiga and Ronaldo to be top goalscorer|
|Gomes: Portugal can deal with Ronaldo absence|
|Sterling reveals Guardiola impact|
|Fiorentina deny approach for Chelsea target Alonso|
|Allardyce confirms Rooney retains England captaincy|
|Hart to join Torino – agent|
|Sanches withdrawn from Portugal squad|
|Sporting CP issue Adrien Silva clarification amid Leicester links|
|Watford confirm Okaka signing|
|Manchester City outcast Zuculini seals Rayo Vallecano loan switch|
|Dembele offers something different - Deschamps|
|Sunderland would just love to get rid of me - Lens|
|No Casillas in Spain squad represents a ´new era´, says Ramos|
|Zenit defender Criscito could return to Italy, claims agent|
|Barcelona reveal Messi hamstring injury|
|Modric named new Croatia captain|
|Napoli announce Rog signing|
|De Boer is building something at Inter - Morratti|
|Keane eyes coaching career after international retirement|
|Bravo left out of Chile squad for family reasons|
|West Brom announce Chadli signing|
|Former Dodgers owner set for Marseille purchase|
|Ferdinand: I reached out to Wenger|
|Holgate has big quality for a young player - Koeman|
|Manchester United want to keep Rojo, says agent|
|Low not concerned by captaincy as Germany bid farewell to greats|
|Aguero pulls out of Argentina squad|
|Howedes: Germany must prove themselves all over again|
|Ventura close to tears on first day of Italy training|
|Torino interested in City outcast Hart|
|Adrien Silva hoping to seal ´exceptional´ Leicester switch|
|Boufal joins Southampton from Lille for club-record fee|
|Villa outcast Lescott joins AEK Athens|
|Milner: I´m learning left-back role as fast as I can|
|Allardyce ready for Hart transfer disruption|
|´Door always open´ for Barkley - Allardyce|
|Xhaka like Petit, claims Wenger|
|Coric: I was a medical away from joining Liverpool|
|Pasalic keen to put injury troubles behind him at Milan|
|Guardiola delighted with Sterling form|
|Rooney should retire from England duty - Shearer|
|Hazard can ´decide´ the title - Ivanovic|
|Allardyce hails ´outstanding´ Antonio|
|Belgium can make history - Henry|
|Nice president: Call Balotelli and tell him we need a striker|
|Modric would like to see out career in Madrid|
|Geromel replaces Caio in Brazil squad|
|Mustafi: Ozil convinced me to join Arsenal|
|Pardew confirms ´one or two´ more signings|
|MLS Review: Kaka brace denies NYC top spot, Timbers beat Sounders|
|Mihajlovic: I won´t waste anymore breath on Maksimovic|
|Okon named Central Coast Mariners coach|
|´Special´ Rashford will get chance - Rooney|
|Injury forces Schurrle out of Germany squad|
|Burke snubs Premier League interest to join RB Leipzig|
|Guardiola: Nasri has a future at City, if he wants it|
|Klopp confident ´all will be good´ with Sturridge|
|Emery confident PSG will bounce back|
|Athletic may strengthen squad - Valverde|
|Fabregas dismisses exit rumours, committed to Conte and Chelsea|
|De Boer encouraged as Inter´s wait continues|
|Barca ´strengthened´ by Luis Enrique´s 100th win|
|Fekir to undergo knee operation|
|Monaco 3 Paris Saint-Germain 1: Ligue 1 champions suffer early loss|
|Aguero facing possible Manchester derby ban|
|Athletic Bilbao 0 Barcelona 1: Rakitic strike extends Barca´s strong start|
|West Ham´s Antonio handed first England call-up|
|Guardiola ´so optimistic´ after Man City´s perfect start|
|Inter 1 Palermo 1: Icardi gets De Boer´s men off the mark|
|Credit Guardiola for boost in form, says Sterling|
|Manchester City 3 West Ham 1: Hosts stay perfect under Guardiola|
|Cavani won´t return to Napoli - De Laurentiis|
|Pulis puts 48-hour deadline on Berahino future|
|Zaza awaits ´new adventure´ at West Ham|
|Karanka open to transfer ´surprises´ after strong Middlesbrough start|
|Dost completes Sporting move|
|Allardyce wanted N´Zonzi for England|
|World Cup could be expanded - Infantino|
|West Brom 0 Middlesbrough 0: Booed Berahino benched for dour draw|
|Gyan´s ´destiny´ in England, Sunderland return an option|
|Zidane wanted Pogba and Madrid are weaker without him - Raiola|
|Juventus end Matuidi pursuit|
|´He´s freaking amazing!´ - Balogun hails Dortmund´s Dembele|
|Thohir thrilled as Inter confirm Joao Mario signing|
|Fabinho expects Monaco stay despite Manchester United links|
|Infantino has Blatter wine cellar removed as part of FIFA reform commitment|
|West Ham seal Zaza loan|
|Joao Mario posts heartfelt thanks to Sporting after record-breaking Inter move|
|Aguero: I´m not competing with Ibrahimovic|
|Mihajlovic: Maksimovic is dead to me|
|Risdon replaces Wright for Socceroos|
|MLS Review: DC United in goal-fest, Impact stun Toronto|
|Schmeichel to undergo surgery|
|Milik revels in ´dream´ brace as he ignores Higuain shadow|
|Rossi to join Celta Vigo|
|Ayestaran: Barcelona target Alcacer unable to compete|
|Simeone: Winless Atletico must remain calm|
|Griezmann: Atletico must improve or face relegation fight|
|Sterling ´feels the love´ at City - Guardiola|
|Stones glad he did not end up at Chelsea|
|James impact earns Zidane´s praise|
|Montella bemoans AC Milan´s indiscipline|
|Leganes 0 Atletico Madrid 0: Returning Griezmann fails to inspire turgid visitors|