Antonio Conte admits that Juventus are battling fatigue ahead of Thursday's visit to Lyon in the UEFA Europa League quarter-finals.
The Serie A leaders suffered only their second league defeat of the campaign on Sunday as the Turin club fell to a 2-0 reverse at the hands of Napoli, ending their 14-match unbeaten run in all competitions.
Coach Conte's men are still very much on course for the title, but the 44-year-old concedes that Juve's congested fixture schedule has taken its toll on his players.
"We were off-colour," Conte told Gazzetta dello Sport after the loss to Napoli. "We are playing so many games right now and always with the same players due to injuries.
"Most of my players are tired as they haven't had a chance to rest."
Juve's poor performance came just four days after a 2-1 win over Parma and Conte will again have to manage his resources as they prepare to face a Lyon side who have only lost one game in the Europa League this season.
The visitors will be boosted by the return of top scorer Carlos Tevez for the first-leg clash after he missed the Napoli match due to suspension, but a number of first-team players remain on the sidelines through injury.
Defender Andrea Barzagli is expected to miss out with a calf injury, while Angelo Ogbonna and Federico Peluso (both thigh) also miss out.
Lyon's performance in the competition this season has been impressive, with the 2-1 last-16 second-leg loss to Viktoria Plzen marking their solitary defeat so far.
And that mattered little as Remi Garde's men progressed 5-3 on aggregate thanks to an impressive 4-1 success in the first leg at the Stade de Gerland.
However, Garde's side approach their first competitive meeting with Juventus on the back of a local derby loss to Saint-Etienne that severely dented their prospects of securing UEFA Champions League football for next season.
Lyon are now nine points adrift of third-placed Lille - who occupy the final Champions League spot - but can secure a European return via the Coupe de la Ligue, where they meet Paris Saint-Germain in the final later this month.
But Lyon's hopes of claiming continental silverware this year have been hampered by a number of injuries, with midfield playmaker Clement Grenier missing the last six games due to an infection in his groin.
Defender Miguel Lopes is set to be absent for the rest of the season with a broken leg, while Gueida Fofana (groin), Mouhamadou Dabo and Milan Bisevac (both hamstring) are all doubtful.
|Coach: R. Garde|
for A. Lacazette 75'
for S. Malbranque 86'
for J. Briand 89'
|Ba left out of Senegal AFCON squad|
|Redknapp frustrated by penalty call|
|Wenger sees Giroud wrongs|
|Premier League schedule a ´disgrace´, says Poyet|
|Championship Review: Bournemouth stay top, Heskey scores on Bolton debut|
|Hughes lauds Bojan performance|
|Koeman: Saints marching on|
|Pardew rues referee error|
|Arsenal 2 QPR 1: Sublime Alexis secures the spoils|
|Martinez questions Walters decision|
|Poyet laments Sunderland mistakes|
|League One Review: Swindon cruise to win over Walsall|
|Irvine aware of need for improvement|
|United still doing ´very bad things´ - Van Gaal|
|Lambert proud of players despite Swansea defeat|
|Warnock bemoans Palace defence|
|Bruce hails Hull´s spirit|
|Pochettino relieved to come away with victory|
|Dyche: We had our pocket pinched|
|Monk hails Fabianski performance|
|Pearson demands greater concentration from Leicester|
|Kompany set for City return|
|Rodgers hails character after battling win|
|League Two Review: Ainsworth frustrated by Luton, Shrewsbury go top|
|Everton 0 Stoke City 1: Lacklustre Everton slip to defeat|
|Sunderland 1 Hull City 3: Triumphant return for Bruce|
|Burnley 0 Liverpool 1: Sterling wins it at Turf Moor|
|Leicester City 1 Tottenham 2: Eriksen piles misery on Pearson´s men|
|Manchester United 3 Newcastle United 1: Rooney extends hosts´ streak|
|West Brom 1 Manchester City 3: Three and easy for in-form champions|
|Swansea City 1 Aston Villa 0: Hosts break Boxing Day duck|
|Crystal Palace 1 Southampton 3: Mane marks return with star performance|
|Allardyce upbeat despite defeat|
|Van Dijk happy at Celtic - Deila|
|Table-topping Chelsea delight Mourinho|
|Chelsea 2 West Ham 0: Mourinho´s men ease to victory|
|Suarez enjoying Messi, Neymar link-up|
|A-League Review: Garcia rescues point for Perth, Adelaide up to second|
|Poyet calls for mid-season break|
|Van Gaal rules out Januzaj move|
|Rodgers: Balotelli may have to get used to bench|
|Lallana: I was trying too hard|
|Walker juggles music, football careers in Sweden|
|Song to face ´brother from another mother´ Fabregas|
|Adriano announces Le Havre deal|
|Pardew braced for Old Trafford test|
|Lescott unfazed by City reunion|
|Tskhadadze appointed Georgia coach|
|United to finish top three - Ferdinand|
|Allardyce: Stamford Bridge stalemate saved my job|
|Southampton need three January signings, says Watson|
|Liverpool can make Champions League, says fanzine editor|
|Walsh: Hull clash crucial for Leicester|
|Toure, Aubameyang and Enyeama make shortlist for African gong|
|Docherty backs Chelsea to win two-horse race|
|Liverpool could benefit from Hyypia influence - Scales|
|Saudi Arabia name Asian Cup squad|
|Forty-year-old Cahill no problem for Postecoglou|