Inter's unbeaten start under new manager Walter Mazzarri continued as they came from behind to defeat Fiorentina 2-1 on Thursday.
The result was kind on Inter, who were dominated in the first half, and Fiorentina claimed a deserved lead in the 59th minute after Giuseppe Rossi converted a penalty.
However, Cambiasso dragged the winners level with 18 minutes remaining with a smart finish, before Jonathan lashed in a late winner to send the Milanese club second in the table.
Inter have now won five of their six matches in all competitions this season, scoring 19 goals and conceding just two.
Mazzarri unsurprisingly made no changes to the side that thrashed Sassuolo 7-0 on Sunday, while Fiorentina manager Vincenzo Montella only tinkered with his team, introducing Joaquin for the dropped Rafal Wolski.
Japan defender Yuto Nagatomo fired an early warning shot for Inter, forcing Fiorentina goalkeeper Neto into a save within the first minute, but it was the visitors who would control the early proceedings.
Rossi had an early chance on goal, linking well with Joaquin before hitting a fierce drive that Inter goalkeeper Samir Handanovic had to palm away, and the duo paired up again shortly after.
This time Handanovic had to keep out Joaquin, who was forced wide by Andrea Ranocchia, and the Spaniard also fizzed an effort across the face of goal as Fiorentina pressed for a goal.
Rossi and Manuel Pasqual – who hobbled off moments later - had further attempts on goal, with Inter restricted to half-chances and an acrobatic Fredy Guarin effort.
Fiorentina, who had continual joy down the right flank, deserved to be in front at the break, and Inter could have no complaints when they took the lead just before the hour-mark.
The goal came from the penalty spot, with Juan penalised for dragging down Joaquin, and Rossi stepped up to dispatch the spot-kick with precision.
Just as Inter looked to be running short of ideas, Cambiasso produced a moment of brilliance with 18 minutes to play for their equaliser.
Hugo Campagnaro won a crucial header among a dithering defence, and Cambiasso chested down before lashing a left-foot volley past Neto.
Campagnaro was then called on at the other end to make an important block that denied Rossi, while Borja Valero's superb cut-back was thrashed straight at Handanovic by substitute Josip Ilicic.
And his save was vital, as Inter charged forward and took the lead thanks to a bullet finish from Brazilian defender Jonathan.
Argentinian Ricky Alvarez played Jonathan in with a terrific ball from the left, and the scorer chested down and avoided the attempted interception by Matias Fernandez before he fired beyond Neto.
Alvaro Pereira and Cambiasso had further attempts on goal as Inter aimed to seal the result, while Ambrosini had a late effort for the losers, but Mazzarri's men held on.
|Coach: W. Mazzarri|
for S. Taïder 61'
for F. Guarín 67'
for Jonathan 85'
|Fiorentina swoop for Brillante|
|Navas set to join Bayern|
|Neymar rejects agent´s anti-Scolari Twitter tirade|
|Allegri undecided on Italy job|
|Fernando idolises City team-mate Toure|
|Arteta: FA Cup will inspire Arsenal´s Premier League tilt|
|Evergrande confirm Gilardino signing|
|Howedes calls for team effort to stop Messi|
|Kuyt: Van Gaal can succeed at United|
|Argentina fined for player no-show|
|Neymar: ´I could be in a wheelchair´|
|Mascherano: I tackled doubts to block Robben|
|Zaccheroni: I leave Japan in a good spot|
|Aguero: Argentina ready to give everything|
|UEFA Europa League Review: Gothenburg leave it late, Sillamae stun Honka|
|Klose lauds Ronaldo after scooping record|
|Iran refute Susic claims|
|Fernandez named Deportivo boss|
|Argentina have no chance, says Robben|
|Hierro to replace Zidane as Real first-team coach|
|Rhodes signs new Rovers deal|
|Arsenal complete Sanchez swoop|
|Inzaghi backs under-fire Balotelli|
|Defeat has overshadowed display - Vlaar|
|Maradona: Germany full of themselves|
|Barry hoping for England recall|
|Green extends QPR stay|
|Shanghai Shenhua 1 Guangzhou Evergrande 2: Rong leaves it late in dramatic win|
|Germany hope for Brazilian support|
|Torino striker Cerci in demand|
|FIFA critcised following Mascherano incident|
|Bernat happy at Bayern despite bad memories|
|Giggs backs Van Gaal to thrive at Old Trafford|
|Tadic can fill Lallana void - Koeman|
|New five-year deal for Nasri|
|Barcelona release injury-hit Cuenca|
|Suarez appeal rejected|
|La Decima a reflection of Di Stefano - Perez|
|Buoyant Mazzarri eager for Inter success|
|Mandzukic joins Atletico|
|Van Gaal criticises third-place play-off|
|Halilhodzic yet to decide future|
|Mandzukic eager for Simeone link-up|
|Davies hoping for Hull deal|
|Poyet hopeful over Altidore fitness|
|Diego close to ´dream´ Fenerbahce move|
|Inter loan out youngsters|
|Fired-up Cole can inspire Villa, claims Lambert|
|Hughes hailed for winning over Brit doubters|
|Hajrovic signs for Bremen|
|Hull can buck Europa League trend, says Meyler|
|Mertesacker talks up German chances|
|Swansea reveal Tottenham contact over Davies, Sigurdsson|
|Lloris pens five-year deal at Tottenham|
|Fernandinho: ´The pain is big´|
|MLS Preview: Portland aim for swift revenge against Seattle|
|Sabella: Germany have an advantage|
|Second Argentine journalist dies in Brazil|
|Aguero: Argentina defied critics|
|Impressive Mascherano thrilled with final´s berth|
|Zuniga offered protection by Colombia|
|Germany vowed not to ´humiliate´ Brazil|
|Hong resigns from South Korea post|
|Third-choice Vlaar ´wasn´t nervous´|
|Van Gaal: I wanted Krul in the shootout|
|Argentina: Key factors in reaching the final|
|Sabella revels in semi-final win|
|Proud Robben feels pain of World Cup exit|
|FIFA World Cup: Netherlands 0 Argentina 0 (after extra time, 2-4 on penalties)|
|Susic signs two-year extension with Bosnia-Herzegovina|
|Hummels in race to make World Cup final|
|Scolari still baffled by Brazil collapse|
|Spendlhofer and Benedetti leave Inter|
|Neymar ´recovering well´ from injury|
|Villarreal sign Jonathan dos Santos|
|Arteta happy at Arsenal, insists agent|
|Birsa makes Chievo loan switch|
|FIFA suspends Nigeria over political interference|
|Di Stefano funeral held in Madrid|
|Hangeland scathing of ´difficult´ Magath|
|Thiago Silva in fan plea|
|Isgrove earns fresh one-year deal at Southampton|
|Morata edges closer to Juve switch|
|Nugent pens two-year extension at Leicester|
|Gomez delight with ´perfect´ Germany|
|Costa Rica to discuss Pinto future|
|Arfield agrees Burnley extension|
|Allardyce targets four more signings|
|K.League Review: Jeonnam close gap on Pohang, Jeonbuk|
|Maradona: Thrashing damages Brazil´s image|
|Kasami makes Olympiacos move|
|Chelsea complete Pasalic signing|
|Helenius makes temporary Aalborg return|
|Higuain set for Napoli stay|
|Basta targets return to Europe with Lazio|
|Lewandowski willing to adapt for Bayern|
|New Hull deal for Jakupovic|
|Atletico agree Mandzukic deal, claims Sammer|
|Fulham seal Stafylidis loan|
|Alves pens new Valencia deal|
|Ochoa to take time over future|
|Brown could miss three months|
|Adams: Norwich will not overspend|
|Gundogan unsure when rehab can step up|
|Stoke chairman wants long Begovic stay|
|Brazilian media reacts to semi-final exit|
|Icardi vows to remain at Inter|
|Robben is player of the World Cup, says Kluivert|
|Klose focused on final after breaking record|
|Prandelli takes aim at Balotelli, Rossi|
|Schweinsteiger sorry for Brazil battering|
|Brazil scarred for life, says Fred|
|Sabella: Argentina ´have already won´|
|Muller stunned by rout|
|Low lauds ice-cool Germany|
|Tearful Luiz apologizes for semi-final loss|
|Scolari sorry for ´catastrophic´ Brazil hammering|
|Brazil join sport´s biggest chokers|
|Reality kills Brazilian dream on a surreal night|
|FIFA World Cup: Brazil 1 Germany 7|