Barcelona will look to preserve their winning start to the new season when they welcome Real Sociedad to Camp Nou on Tuesday.
Only Atletico Madrid have matched Gerardo Martino's side so far, with Real Madrid two points back in third.
Barcelona have been in devastating form at the start of the campaign, scoring 18 goals in their opening five matches while only conceding four.
They emphatically won this fixture 5-1 last season but Sociedad got their revenge in January and became only the second side to beat Barca in the league, prevailing 3-2.
Cesc Fabregas will not feature for Martino's side after he was left out in order to have a rest, with Sergio Busquets coming in having missed the win over Rayo Vallecano.
Carles Puyol remains sidelined as he continues his rehabilitation from knee surgery.
Atletico will hope to keep pace with Barcelona when they face Osasuna at the Vicente Calderon.
Diego Simeone's side are unbeaten in their last seven meetings with Tuesday's opponents and they will hope that Diego Costa continues his rich vein of form to fire them to victory.
The Brazilian striker has found the back of the net five times this season, with only Lionel Messi scoring more.
Their city rivals Real Madrid travel to struggling Elche on Wednesday for their first meeting since 1989.
Carlo Ancelotti's side will be without world-record signing Gareth Bale (groin) but may have Iker Casillas and Sergio Ramos available after both men returned to training on Monday.
Madrid will be hoping to avoid a repeat of the last time they met a promoted side – they were were held to a 2-2 draw by Villarreal.
Marcelino Garcia Toral's side have made an excellent start on their return to the top flight and will look to continue that when they face Espanyol.
Like their opponents, Espanyol have started the season well, and have also yet to taste defeat this season.
Real Betis travel north to Bilbao to become the second side to face Athletic at their new San Mames Barria stadium.
Athletic won their first game in the new stadium against Celta Vigo but they have not beaten Betis in their last four attempts so will be wary of Pepe Mel's side.
Valencia put a disappointing performance in Europe behind them on Sunday with a win over Sevilla and the under-pressure Miroslav Dukic will hope that they can repeat that form when they travel to Granada.
Elsewhere, Levante welcome Real Valladolid to the Estadio Ciudad de Valencia on Tuesday, while Almeria travel to Malaga on Wednesday.
Rock-bottom Sevilla go in search of their first win of the season against Rayo Vallecano, and Getafe entertain Celta.
|Coach: G. Martino|
for J. Mascherano 35'
for Neymar 74'
for L. Messi 80'
|Serie A Review: El Shaarawy at the double in Milan victory, Fiorentina edge five-goal thriller|
|Taylor close to signing new Swansea contract|
|Milan 3 Torino 0: El Shaarawy grabs brace as Inzaghi´s men ease to victory|
|Bruce expresses sympathy with Hull owner and fans following relegation|
|Preston North End 4 Swindon Town 0: Beckford hat-trick seals promotion|
|Darmstadt promoted back to the Bundesliga after 33-year exile|
|Sherwood to assess Given injury ahead of FA Cup final|
|Europa League qualification would cap ´special´ season - Koeman|
|South Africa 0 Botswana 0 (6-7 on penalties): Hosts exit COSAFA Cup at first hurdle|
|Pearson hopeful of Cambiasso stay|
|Ings emotional after victorious ´last game´|
|Pochettino happy to finish fifth|
|West Brom release Mulumbu|
|Monk: Palace defeat not a reflection on season|
|LVG awaits news on ´minor´ Di Maria injury, refuses to comment on Falcao exit reports|
|Pulis accepts blame for West Brom´s Arsenal collapse|
|Toure and Milner were not saying goodbye - Pellegrini|
|Ramsey calls for patience in QPR rebuild|
|Allardyce: Time is right for West Ham exit|
|Mourinho already preparing for title defence|
|Eredivisie Review: Heerenveen to play Vitesse for Europa League place|
|Hughes hails Stoke showing|
|Carver still hoping to land Newcastle job|
|Sunderland squad needs better balance, says Advocaat|
|Pardew ´never dreamt´ of top-half finish at Palace|
|Survival Sunday: How the final-day Premier League relegation battle played out|
|Arsenal wanted Walcott stay regardless of hat-trick - Wenger|
|Bruce: Hull have not been good enough|
|De Gea has to say something - Van Gaal|
|Rodgers apologises after ´embarrassing´ defeat|
|Chelsea 3 Sunderland 1: Remy double secures win as Drogba bids farewell|
|Stoke City 6 Liverpool 1: Gerrard nets consolation in final-game thrashing|
|West Ham confirm Allardyce exit|
|Newcastle United 2 West Ham 0: Gutierrez on target as Carver´s men stay up|
|Crystal Palace 1 Swansea City 0: Chamakh earns season-closing win|
|Manchester City 2 Southampton 0: Lampard bids Premier League farewell with goal|
|Hull City 0 Manchester United 0: Bruce´s men relegated|
|Aston Villa 0 Burnley 1: Ings heads winner|
|Everton 0 Tottenham 1: Kane header seals fifth place|
|Leicester City 5 QPR 1: Vardy celebrates England call-up in style|
|Arsenal 4 West Brom 1: Wilshere screamer and trio for Theo secures third|
|Drogba carried from the pitch by Chelsea team-mates|
|Scottish Premiership Review: United take Dundee derby spoils, Celtic smash Inverness|
|Ashley not leaving Newcastle until club wins something|
|Klopp urges fans not to draw comparisons with Tuchel|
|Dortmund complete Castro capture|
|Stevens leaves Stuttgart after securing safety|
|Alves ruled out of Copa with serious knee injury|
|Drogba to leave Chelsea|
|Ashley is from another planet - Keegan|
|Sydney withdraw Janko offer amid talk of Toni|
|Cameron pens Stoke extension|
|Wimmer: I´m going to Tottenham|
|Returning Grabban ready for play-off final - Neil|
|Ferdinand ´overwhelmed´ by support following wife´s death|
|Odegaard enjoys ´nervous´ Real Madrid debut|
|Bamford fit but may be overlooked for play-off final|
|Barcelona´s best better than Real´s - Luis Enrique|
|Ancelotti laments key injuries in title failure|
|AFC Champions League Preview: Evergrande, Al Hilal desperate for wins|
|MLS Review: DC United deny nine-man Revolution, Rapids break drought|
|Bielsa hints at Marseille departure, congratulates Ligue 1|
|Silva, Matuidi eye fourth trophy|
|Jonas deserved golden boot - Jorge Jesus|
|Primeira Liga Review: Benfica celebrate title with home win|
|Ligue 1 Review: Monaco seal final Champions League spot, Marseille take fourth|
|Ancelotti to take sabbatical if sacked by Real|
|Mancini annoyed by ´absurd´ Inter mistakes|
|Simeone hails ´incredible season´|
|Replacing Xavi will be impossible - Luis Enrique|
|Ronaldo hopes Ancelotti will stay|
|Guardiola: We´ll be back stronger|
|Paris Saint-Germain 3 Reims 2: Cavani double sees champions celebrate title with routine win|
|Garitano stands down following Eibar relegation|
|Genoa 3 Inter 2: Kucka strikes blow to visitors´ Europa quest|
|Real Madrid 7 Getafe 3: Ronaldo nets treble and Odegaard makes history|
|Southend United 1 Wycombe Wanderers 1 (aet, 7-6 on penalties): Last-gasp Pigott and Bentley the hero|
|Odegaard becomes Real´s youngest player|
|Gargano omitted from Uruguay Copa America squad|
|La Liga Review: Depor save themselves with stunning comeback at Barca|
|Barcelona 2 Deportivo La Coruna 2: Salomao saves visitors as Xavi bids Camp Nou farewell|
|Granada 0 Atletico Madrid 0: Atleti secure third as hosts survive|
|Juventus 3 Napoli 1: Champions turn on the style|
|Tearful Klopp struggled to say goodbye|
|Scottish Premiership Review: Rangers to meet Motherwell in play-off final|
|Bundesliga Review: Freiburg and Paderborn relegated|
|Borussia Dortmund 3 Werder Bremen 2: Dortmund seal European spot as Klopp says farewell|
|Bayern Munich 2 Mainz 0: Schweinsteiger nets as champions celebrate title|
|Championship play-off final Preview: Karanka and Neil eye swift ascent to Premier League|
|Volland commits to Hoffenheim|
|Monk: Michu likely to move on|
|Allardyce not interested in Newcastle revenge|
|Sherwood confident of Benteke Villa stay|
|Rodgers calls on Liverpool fans to support Sterling|
|Khedira ´frozen out´ by Real|
|Hamstring injury rules Suarez out of Deportivo clash|
|Former Southampton managers hail ´excellent season´|
|Mourinho wants to remain in England after Chelsea|
|Rodgers ´150 per cent sure´ his job is safe|
|Maldini would ´love´ to help Milan|
|Doyle set for Rapids debut versus Whitecaps|
|MLS Review: Champions end winless run on day of late drama|
|Jemez doubted Rayo future|
|Zenga could replace Mihajlovic - Osti|
|Blanc wants to avoid Chelsea-like finish|
|Menez happy in Milan|
|Sherwood: Vlaar wants to stay|
|Arsenal v West Brom: Wenger calls for focus|