A 90th-minute goal from Roberto Ovelar has seen Juan Aurich stun Universitario 1-0 in Peru's Primera Division.
Both second phase group leaders in the Primera Division dropped points as Group A's top team Real Garcilaso were held to a 1-1 draw away to Union Comercio and Group B's Universitario suffered their first defeat in nine games.
But Universitario's loss did not hurt the capital club too much as the next four clubs in Group B all failed to win.
Universitario had to play about an hour with 10 players after Nestor Duarte was shown a red card in the 32nd minute for a raised arm to Ovelar's face.
Despite having one more player for most of the match, Juan Aurich rode their luck at times on Thursday with Universitario wasting a number of counter-attack opportunities after half-time.
But in the final minute of regular time, Juan Aurich finally made their extra man count when Ovelar did well to control Jeikson Reyes' cross from the left wing on his chest and then side-footed the ball into the net.
The loss left Universitario on 57 points but with second-placed Inti Gas also losing 3-1 away to Universidad San Martin, the Group B leaders remain eight points clear at the top of the table.
UTC Cajamarca, Leon de Huanuco and Cienciano also failed to make significant inroads into Universitario's leading margin.
Cajamarca and Cienciano drew 2-2, while Leon lost 1-0 to Jose Galvez.
In Group A, bottom-placed club Union Comercio shared the points with Real Garcilaso.
Roberto Jimenez produced a smart finish to give Union Comercio the lead in the 13th minute and although Mauricio Montes equalised for the visitors six minutes before half-time, the home side held on for a draw.
Second-placed Sporting Cristal, who have a game in hand on Real Garcilaso, could move within a point of the Group A-leaders if they knock them off on Sunday.
In the other midweek game, Sport Huancayo defeated Pacifico 2-1.
|Coach: R. Mosquera|
for J. Viza 51'
for A. Sánchez 65'
for R. Merino 76'
|Lemina rejects Gabon call-up|
|Toure a doubt for Sunderland clash|
|Millen ´ready´ to manage Palace|
|Carver urges Newcastle to kick on|
|Bellarabi extends Leverkusen deal|
|Wenger hails ´committed´ Arsenal|
|Diouf will be missed - Hughes|
|Millen elated at resolute Palace performance|
|Lambert: Big point for Villa|
|Martinez rues Cisse decision|
|Dyche delighted by Burnley character|
|Allardyce: Officials got it horribly wrong|
|Poyet rues dropped points at Villa|
|Bruce frustrated as dominant display yields no points|
|Pellegrini laments key turning points in Burnley setback|
|Newcastle United 3 Everton 2: Pardew´s men impress at St James´ Park|
|League One Review: Swindon climb into second, MK Dons suffer surprise defeat|
|Championship Review: Bournemouth go four points clear, Boro held|
|Koeman hails Southampton spirit|
|Inverness Caledonian Thistle 0 Aberdeen 1: Pawlett strikes sends McInnes´ men second|
|Mourinho fumes at ´campaign´ against Chelsea|
|Manchester City 2 Burnley 2: Barnes claims a point to deny champions|
|West Ham 1 Arsenal 2: Wenger´s men climb above hosts|
|Hull City 0 Leicester City 1: Mahrez fires Pearson´s men to victory|
|QPR 0 Crystal Palace 0: Millen makes solid start as temporary Palace boss|
|Aston Villa 0 Sunderland 0: Delph sees red in stalemate|
|Stoke 2 West Brom 0: Diouf brace secures back-to-back wins|
|Southampton 1 Chelsea 1: Mourinho´s men end 2014 on top|
|Van Gaal frustrated with wasteful finishing|
|Pochettino content with goalless draw|
|Tottenham 0 Manchester United 0: Honours even at White Hart Lane|
|Klose vows to fight for Lazio place|
|Hughton admits interest in Palace and Brighton roles|
|Injuries not behind retirement plans, says Rolfes|
|Podolski: Arsenal exit not a formality|
|Wellington Phoenix 1 Western Sydney Wanderers 0: Krishna wins it|
|Taylor wary of ´beast´ Lukaku|
|Al Habsi to lead Oman at Asian Cup|
|Lacazette will stay at Lyon - Aulas|
|Southampton like Atletico, says Alderweireld|
|World Cup held PSG back - Blanc|
|Everton facing ´pivotal´ moment - Martinez|
|Zamora urges QPR to tie down Austin|
|Badstuber, Alaba set for New Year return|
|Burgos: Atletico will get the best out of Torres|
|Chelsea to offer Terry new deal - Mourinho|
|Rodgers excited by Sterling development|
|Strinic close to finalising Napoli switch|
|Torres to join Milan on permanent deal|
|Scottish Premiership Review: Celtic held to shock draw, rivals fail to capitalise|
|Wenger sings Song´s praises|
|Pochettino calls for bravery|
|West Ham could lose Allardyce - Sullivan|
|League One Preview: Saunders takes charge for Colchester clash|
|Aguirre denies any involvement in La Liga match-fixing scandal|
|Mourinho impressed by Koeman´s Southampton|
|QPR v Crystal Palace: Millen recast in familiar role|
|West Ham v Arsenal: Allardyce eyes further home comfort|
|Elusive Coppa Italia on Juventus´ wish list - Marotta|
|Jones eyes swift response|
|Millen focused on QPR clash|
|League Two Preview: Shrewsbury, Wycombe and Burton vie for year-end top spot|
|Mancini not expecting big-money signings at Inter|
|Tottenham v Manchester United: Carrick expects tough return|
|Pearson eager to see Leicester resolve|
|Newcastle United v Everton: Martinez demands clinical touch|
|Liverpool v Swansea City: Rodgers backs returning Mignolet|
|Bayern can still improve - Sammer|
|Warnock sacked by Palace|
|Aston Villa v Sunderland: No club too big to go down, says Lambert|
|Hull City v Leicester City: Pearson vows to keep going|
|Stoke City v West Brom: Hughes targets elusive back-to-back wins|
|Rodgers dismisses Balotelli exit rumours|
|Modric will not rush Madrid return|
|Dyche pleased with Vokes return|
|Southampton v Chelsea: Koeman vows to go on the offensive|
|A-League Review: Six-goal Gosford thriller, Victory leave it late|
|Manchester City v Burnley: Pellegrini warns against complacency|
|Dortmund can fight on two fronts - Watzke|
|Sterling hails improved Liverpool belief|
|Rosicky eager to build on QPR winner|
|Wenger: ´We made it hard for ourselves´|
|Kane: Spurs eye top four|
|Di Maria in doubt for Spurs clash|