A debut goal from Gareth Bale was not enough to hand Real Madrid victory as they were held to a 2-2 draw by Villarreal on Saturday.
The Welshman made his first competitive start for the club since his world record move from Tottenham, and he began repaying his huge fee by cancelling out Cani's opener at El Madrigal just before half-time.
Cristiano Ronaldo refused to be overshadowed as he put Real ahead with a breakaway goal after 64 minutes, but their lead was short-lived as Giovani dos Santos equalised just nine minutes later.
Carlo Ancelotti opted to start Bale on the right, with Isco in the centre and Ronaldo on the left behind lone striker Karim Benzema.
Midfielder Asier Illarramendi also made his first start for Real.
Villarreal made just one change to the side that beat Osasuna 3-0 in their last La Liga fixture, with Dos Santos replacing Jeremy Perbet.
Despite the wealth of talent in Real's ranks, it was the home side who made the more positive opening and twice in the opening 15 minutes Jonathan Pereira was denied at the near post by Diego Lopez.
But they deservedly got the breakthrough in the 21st minute.
Real failed to clear their lines with Pereira and Bruno Soriano both looking to pounce, but the ball spilled kindly to Cani, who smashed home into the bottom corner.
It could have been even worse just short of the half-hour mark when the influential Pereira played a sublime backheel to Javier Aquino, whose initial shot was saved by Lopez before the goalkeeper stopped the rebound.
Real were reeling but they should have been level on 34 minutes when Sergio Ramos chipped a superb pass over the top for Ronaldo, but he uncharacteristically steered his header wide.
Against the run of play, Real did get the equaliser, when Bale opened his account for his new club.
Daniel Carvajal broke down the right before putting in a teasing low cross and the Welshman nipped in ahead of Mario and slid to poke home with his right foot from close range.
Villarreal had shouts for a penalty shortly after the restart when a Dos Santos effort struck Bale on the arm before Bale nearly irked the home fans further when his 25-yard drive went narrowly over the crossbar.
And the home side should have been back in front in the 54th minute. Dos Santos backheeled smartly to Pereira and his centre found Jaume Costa unmarked, but from eight yards he somehow side-footed wide.
Bale soon departed, withdrawn by Ancelotti, but that was the signal for Ronaldo to take over as he punished the hosts in the 64th minute.
He broke from his own half and laid the ball into the path of Benzema, whose initial shot was parried back to Ronaldo to fire a deflected effort that put Real ahead.
However, the lead lasted less than 10 minutes before Lopez parried Cani's shot into the path of Dos Santos, who drilled home the equaliser.
Villarreal pushed forward for a winner in the closing stages and Cani was denied a second when Lopez produced an outstanding save to stop his rasping drive.
At the other end, Ronaldo almost got the winner for Real in the 87th minute, but his fierce 20-yard effort was parried to safety by Sergio Asenjo.
|Dzeko close to City return|
|Real hit back at Platini over Ballon d´Or comments|
|Ancelotti: Tired Kroos will play|
|United defender Shaw out for ´a few weeks´|
|Melbourne Victory 3 Adelaide United 2: Hosts edge five-goal thriller to go top|
|Mexes determined to stay at Milan|
|Guardiola positive despite City defeat|
|Hull striker Hernandez out of United clash|
|River Plate 1 Boca Juniors 0 (agg 1-0): Pisculichi goal sends hosts into final|
|Wenger confirms Arteta lay-off|
|Negredo not ´obsessed´ with ending barren run|
|Kroos admits fatigue|
|Keane quits Villa role|
|Henry vows to help Arsenal after retirement|
|Everton can go far in Europe - Jagielka|
|Pardew expects Carroll return|
|Michu undergoes ankle surgery|
|Brandao sentenced to prison|
|Allardyce slams ´rather silly´ Tomkins|
|Rodgers similar to Wenger - Toure|
|J.League Preview: Flying Gamba chasing Urawa|
|Benitez happy to progress|
|Montella: Fiorentina have ´impressive mentality´|
|Pele ´doing fine´, receiving kidney treatment|
|Ausilio praises Handanovic´s ´remarkable statistics´|
|We need to improve - Stambouli|
|Estoril versus PSV postponed due to rain|
|UEFA Europa League Review: Feyenoord and Everton qualify in style|
|Martinez hails Everton perfection|
|Tottenham 1 Partizan 0: Stambouli settles it for Spurs|
|Inter 2 Dnipro 1: Osvaldo strikes as 10-man hosts earn hard-fought win|
|Tottenham-Partizan clash temporarily suspended due to pitch invasions|
|McKinlay named Moyes´ assistant|
|Poyet issues Chelsea challenge|
|Wolfsburg 0 Everton 2: Martinez´s men secure top spot|
|Lambert defends Bent loan move|
|Sunderland v Chelsea: Johnson eyes next major scalp|
|Riera released by Udinese|
|QPR v Leicester City: Pearson aiming to build on positives|
|Galatasaray and Anderlecht face disciplinary proceedings|
|Liverpool v Stoke City: Hughes plotting Anfield success|
|Vermaelen out for four to six months|
|Swansea City v Crystal Palace: Monk looking for positive response|
|Printant to remain Bastia head coach|
|Irvine knew nothing of Berahino drink-driving case|
|Pele admitted to special care unit|
|West Ham v Newcastle United: Allardyce pinpoints vital phase|
|Skripnik agrees three-year extension at Werder|
|Monk rubbishes talk of Michu return|
|FA charges Whelan over comments|
|Burnley v Aston Villa: Lambert laments list of absentees|
|Manchester United v Hull City: Bruce wary of in-form Rooney|
|Hughes hopeful over unwell trio|
|Grant named as Ghana coach|
|Bielsa expecting tough Nantes challenge|
|Basel charged by UEFA following pitch invasion|
|West Brom v Arsenal: Mertesacker refocusing attention after midweek win|
|Colaco banned by FIFA|
|Championship Preview: Derby head to happy hunting ground|
|Hertha Berlin v Bayern Munich: Hosts out to take advantage|
|Taylor injury ´not as bad as first feared´|
|Wilshere out for three months|
|Torosidis suffers calf strain|
|Malaga v Real Madrid: Ancelotti´s men in search of sweet 16|
|England climb FIFA rankings, Germany remain number one|
|Bolasie staying put - Warnock|
|Sewe Sport v Al Ahly: Ivorians eye more history|
|Schalke lose Matip with broken foot|
|Paris Saint-Germain v Nice: Ibrahimovic looks to end Ligue 1 goal drought|
|K. League Preview: Seoul, Steelers tussle for third|
|No complaints over FA charge for Allardyce|
|Redknapp ready for crucial run|
|Zapata targets regular first-team role at Milan|
|Fabregas revels in career-best form|
|Eriksen claims Tottenham struggling to ´connect´|
|MLS Preview: Schmid labels Galaxy ´physical´|
|Costa Rican Primera Division Review: Cartagines secure semi-finals berth|
|Serie A Preview: Roma out to stay in touch with Juve|
|The Strongest 1 Bolivar 1: Capdevila strike saves leaders|
|Sao Paulo 1 Atletico Nacional 0 (agg 1-1, 1-4 on penalties): Colombians reach final|
|Cruzeiro 0 Atletico Mineiro 1 (agg 0-3): Culpi´s men win first Copa do Brasil|
|Malmo´s Hareide furious with referee´s injustice|
|Dermendzhiev elated with Ludogorets display|
|Defour withdrawal stalled Anderlecht|
|Atletico achievement delights Simeone|
|Atletico did ´many´ things well - Michel|
|Raul Garcia promises no let-up from Atletico|
|Missed chances disappoint Rolfes|
|La Liga Preview: Real out to break club record at Malaga|
|Ancelotti praises defence after record-equalling win|
|Klopp: Arsenal deserved it|
|Peruvian Primera Division Review: Alianza Lima falter in Clausura race|
|Allegri targeting top spot after Malmo win|
|Rodgers pleased despite Ludogorets late show|
|Wenger rues Arteta injury|
|Ludogorets 2 Liverpool 2: More misery for Rodgers´ men|
|Malmo 0 Juventus 2: Tevez fires Allegri´s side closer to qualification|
|Anderlecht 2 Galatasaray 0: Mbemba secures third place for hosts|
|Bayer Leverkusen 0 Monaco 1: Ocampos strike stuns dominant hosts|
|Atletico Madrid 4 Olympiacos 0: Hat-trick hero Mandzukic books last-16 spot|
|Basel 0 Real Madrid 1: Ronaldo strike equals club record|
|Arsenal 2 Borussia Dortmund 0: Sanogo and Alexis seal progress|
|´We must believe´ – Villas-Boas wants Zenit progression|
|Bundesliga Preview: Schalke and Bayern out to bounce back from Euro setbacks|
|Jesus bemoans wasted Benfica chances|
|League Two Preview: Promotion rivals meet, leaders tackle basement club|
|Ligue 1 Preview: PSG and Marseille both fighting for top spot|
|Mitchell lands Tottenham role|
|Zenit 1 Benfica 0: Danny eliminates Portuguese champions|
|Deila concerned over Commons´ future|
|Everton quartet doubtful for Tottenham clash|
|Pochettino calls for extra rest|
|FA charges Everton and West Ham|
|Money not a factor for Van der Vaart|
|League One Preview: Bristol City out to stop the rot at Peterborough|
|Heldt: Chelsea hammering unacceptable|
|Mancini encouraged by Inter|
|Cheltenham appoint Buckle|
|Date set for Tonev appeal hearing|
|K. League Review: Steelers preserve advantage, Seongnam boost survival hopes|
|Moses out for several weeks|
|Drogba focused on claiming trophies|
|Bent makes Brighton switch|
|Kone included in Everton squad for Wolfsburg clash|
|Shaqiri can ´probably´ leave Bayern, says Beckenbauer|
|Ramsey backs under-fire Wenger|
|Fabregas clears the air with Ramos|
|Cavani urges Ligue 1 focus|
|Olsson out until new year|
|Sao Paulo´s Toloi confident ahead of second leg|
|Aguero our ´special player´, says Kompany|
|APOEL eye Europa League despite winless road streak|
|Silva disappointed by ´childish´ errors|
|Slutsky happy to keep ´intrigue´ alive|
|A-League Preview: Brisbane begin life after Mulvey|
|Eredivisie Preview: Ajax targeting improvement|
|Shakhtar did not lack motivation - Shevchuk|
|Bayern lament two errors, Guardiola proud|
|Valcke: It will ´take years´ to rebuild FIFA´s reputation|
|Luis Enrique ´never fed up´ of Messi magic|
|Valverde pleased with Bilbao triumph|
|Messi revels in Champions League milestone|
|Loss was a ´crying shame´ - De Boer|
|Suarez relieved to get off the mark for Barca|
|Pellegrini puts Aguero among best in the world|
|Cavani wants top spot|