Gareth Bale could make his Real Madrid bow on Saturday as they travel to Villarreal, with both having made 100 per cent starts to the term.
Following his world-record transfer from Tottenham, the Wales international is expected to be involved for Carlo Ancelotti's side, having featured for his country against Serbia on Tuesday.
The 24-year-old could even line-up at full back after Marcelo and Fabio Coentrao both suffered injuries during the international break.
Bale has admitted he might not be fully fit, but insisted he would be happy to play any role his manager needs him to on Saturday.
"We have to wait until the match day to see whether I'm picked or not," he said. "But hopefully I can get my fitness up straight away and get a place in the team.
"I have spoken to the boss about where I'm best on the pitch but I will play anywhere I'm asked."
Both sides have started the season with three wins out of three, but with Madrid dominating their opponents in recent meetings, they will be favourites to maintain their winning start.
Real have won 17 of their 26 meetings, and have not lost any of their last six encounters.
Villarreal only lost seven games on the way to a second-place finish and automatic promotion from the Segunda Division last season and they have started the new campaign well.
The Estadio el Madrigal has been a tough place for teams to visit in the past 12 months with only three sides having left with all three points, and captain Bruno Soriano remains confident they can surprise Real.
"It's a chance to show that we can compete with anyone and that we can fight against a team like Madrid," he said.
"Last year, we were dreaming about playing these teams and now the opportunity has arrived and we want to put in a great performance.
"Personally I prefer it if an opponent is at full strength and that the best come so we can take them on.
"Although even if Madrid has some players out, I am sure they will have the same level of quality."
Xabi Alonso (foot) and Raphael Varane (knee) will definitely be missing for Madrid, however Cristiano Ronaldo and Isco are expected to be available having taken part in training on Thursday.
Bojan Jokic (hamstring) and Francisco Farinos (Achilles) are doubts for the hosts having already missed the opening matches of the season.
|9||G. dos Santos||70'|
for Jonathan Pereira 65'
for Trigueros 71'
for G. dos Santos 75'
|Vitesse hopeful over Solanke loan deal|
|Pedro will decide his own future - Luis Enrique|
|Iniesta handed Barcelona armband|
|Kukesi punished after Europa League abandonment|
|Leno hints at Leverkusen exit|
|Benitez explains Ronaldo absence|
|Pochettino backs Kane to be among world´s best|
|Messi not ruled out of Mexico friendly - Martino|
|China v North Korea: Kim´s side look for another win|
|River Plate v Tigres UANL: Copa Libertadores final evenly poised|
|Torres: I´d give my life to win La Liga with Atletico|
|Real target Ceballos focused on Betis - Mel|
|Platini can lead FIFA change - Fernandez|
|Mel: Betis won´t be signing Osvaldo|
|Ferrero defends Samp boss Zenga|
|Pochettino expects Spurs improvement|
|Bale ideal for United - Robson|
|Ferdinand: Di Maria will regret United failure|
|Benitez pleased with goalkeepers as De Gea transfer saga continues|
|Guardiola tips fit Schweinsteiger to shine|
|Confident Oxlade-Chamberlain hits back at Keane|
|Ferdinand: Stones would be ´a lunatic´ to join Chelsea|
|Qarabag v Celtic: Gordon wants positivity from Scottish champions|
|Higuain rejects extension from Napoli|
|Zamora returns to Brighton|
|West Ham can cope without Valencia - Gold|
|Wickham loses on Palace debut|
|Guardiola: No problem with Matthaus and Effenberg comments|
|Cartabia excited by Deportivo loan|
|Lyon confirm Rafael deal|
|Hysaj agrees deal to follow Sarri to Napoli|
|Rafael says his goodbyes to Manchester United|
|Dos Santos ready to get going with Galaxy|
|Pochettino rejects Soldado exit talk|
|Metatarsal misery for Mulumbu|
|Benitez: Benzema and Bale going nowhere|
|Mihajlovic: Ibrahimovic would make Milan title contenders|
|Hughes not taking any risks with Bojan|
|Guardiola relishing Audi Cup test|
|Di Maria ´taking a step up´ - Silva|
|Leicester bring in defender Benalouane|
|Deulofeu doubtful for Premier League opener|
|West Ham striker Valencia out for three months|
|UEFA: Qarabag-Celtic to go ahead|
|Palace seal Wickham swoop|
|Ronaldo and Benzema to miss Audi Cup|
|Marotta: Juventus could lose Pogba|
|Kante completes Leicester switch|
|Khedira ruled out for two months|
|FA accepts Mourinho criticism of Wembley surface|
|Robben rubbishes injury talk|
|Marchisio expects Milan title challenge|
|Rafael set for Lyon move|
|Celtic ´seeking reassurances´ over Qarabag pitch|
|Wenger beating Mourinho does not affect Chelsea - Zouma|
|Rooney moved by Everton welcome|
|Mancini not worried by lack of Inter goals|
|Coloccini wants to finish career at Newcastle - McClaren|
|Ramsey: Pressure to win trophies is nothing new|
|Terry: Wembley defeat could be a ´blessing in disguise´|
|Blatter not running for IOC re-election|
|Bendtner: Wolfsburg can challenge Bayern for Bundesliga honours|
|Liverpool relishing Britannia return, says Henderson|
|Everton big enough to keep Stones - Martinez|
|MLS Review: Fire stun Dallas as goals dry up|
|New Atletico signings excite Raul Garcia|
|Cahill expects Arsenal title challenge|
|Jovetic happy with Inter debut|
|Luis Enrique: Barca defence must improve|
|Yanev calls for calm after ugly scenes in friendly|
|Coppa Italia Review: Cittadella romp to victory, Brescia rely on penalties|
|Arsenal have learned how to play against big teams - Ramsey|
|Shawcross to visit specialist over back woe|
|Fiorentina 2 Barcelona 1: Bernardeschi double sends Barca to another defeat|
|Mancini hints at Melo interest|
|Rodgers hails ´incredible´ Benteke strike|
|Galatasary 1 Inter 0: Sneijder sinks former club|
|Wenger defends Arsenal approach|
|Wembley loss has no bearing on new season - Terry|
|Porto cruise to friendly win over Stoke|
|Mourinho denies Wenger ´snub´ suggestions|
|Arsenal abandoned their philosophy to win Community Shield - Mourinho|
|Mourinho throws Community Shield medal into Wembley crowd|
|Swindon Town 1 Liverpool 2: Benteke nets stunner on debut|
|Scottish Premiership Review: Hearts win thriller on top-flight return|
|Ujah at the double as Bremen beat West Ham|
|Mourinho: We were the better team|
|Wenger hails defensive solidity|
|Rooney returns as Villarreal spoil Ferguson´s party|
|Rodriguez stunner earns Southampton draw as Caulker makes debut|
|Arsenal 1 Chelsea 0: Case of 14th time lucky for Wenger against Mourinho|
|Taechaubol announces Milan agreement|
|Jojic fires Cologne to latest victory|
|China 0 South Korea 2: Kim and Lee seal victory|
|Origi getting up to speed|
|Costa a doubt for start of season - Mourinho|
|North Korea 2 Japan 1: Halilhodzic´s men spurn lead|
|Allam brands FA ´amateurs´ as name-change row rumbles on|
|Fournier ´worried´ by Lyon pre-season|
|Swansea still working on Michu exit - Monk|
|Neuer furious at Bayern Supercup defeat|
|Wenger: Ozil signing not a mistake|
|UEFA Champions League Preview: Shakhtar ready for Fenerbahce decider|
|Lampard targets MLS play-offs for City|
|MLS Review: Goals galore as DC United win 10-goal thriller|
|Ronaldinho returns and helps Fluminense to win|
|Keane: United won´t overtake Chelsea|
|Casillas has the ´enthusiasm of a 20-year-old´ - Lopetegui|
|Blanc hopeful over Ibrahimovic knee injury|
|Guardiola laments late goal in Supercup defeat|
|Tuchel plans to keep Bender|
|Hecking happy with Wolfsburg discipline after Supercup win|
|Arsenal players too interested in selfies and six-packs - Keane|
|Confusion over Ibrahimovic´s PSG future|