Argentina have booked a place at the 2014 World Cup after a 5-2 win over Paraguay in Asuncion on Tuesday.
Alejandro Sabella's men were the dominant side at Estadio Defensores del Chaco, winning thanks to a brace of Lionel Messi penalties, plus goals from Sergio Aguero, Angel Di Maria and Maxi Rodriguez.
Argentina goalkeeper Sergio Romero's howler gifted an equaliser to Paraguay in the first half through Jose Nunez but Di Maria and Messi put the result beyond doubt shortly after the break as their side stayed top of CONMEBOL World Cup qualifying.
Roque Santa Cruz scored a late consolation goal for Paraguay, who cannot qualify for the World Cup.
Now seven points clear of fifth-placed Uruguay with two games remaining, Argentina join hosts Brazil as the two South American teams with a place booked at the 2014 tournament.
Argentina struck first on 12 minutes after a fast counter-attack led to Paraguay being exposed on the break.
It was a three-on-one break and Di Maria's pass found Aguero at the back post, with the Manchester City forward brought down by the advancing Roberto Fernandez.
Messi stepped up and placed his penalty into the bottom corner as Fernandez dived the wrong way, giving him his 36th goal for Argentina.
The goal sent the Barcelona star into clear second on the all-time leading goalscorers list for his country, ahead of Hernan Crespo (35) but still some way behind Gabriel Batistuta (56).
Argentina's lead only lasted five minutes before a howler from Romero gifted Paraguay their equaliser.
Nunez flicked Miguel Samudio's cross goal-ward and Romero should have dealt with the effort but it bounced over the diving goalkeeper and into the net.
Argentina should have restored their lead three minutes later, but – with an open goal to aim at – Inter striker Rodrigo Palacio put his header wide from close range.
Paraguay captain Santa Cruz was denied by Romero on the half-hour mark, with the goalkeeper tipping the Malaga striker's header over.
It was the combination between Messi and Aguero which led to the latter giving Argentina a 2-1 lead, just moments after another nervy moment by Romero when he dropped a cross.
Messi cushioned down a pass with his chest for Aguero, who took a touch before firing into the bottom corner with his left foot.
Argentina were being given far too much space in the attacking third and Messi had two strikes at goal saved by Fernandez before half-time.
Aguero thought he had given Argentina a two-goal lead on the stroke of half-time but he was correctly ruled offside.
If Paraguay held some hope heading into the second half, it was dashed inside eight minutes after the break.
Di Maria netted in a one-on-one with Fernandez after a lovely Fernando Gago pass before Messi scored from the penalty spot again.
It was a soft penalty awarded against Salustiano Candia for a foul on Messi but came after Paraguay were again left exposed and outnumbered at the back.
Messi chose the other way with his penalty – shooting to Fernandez's left – but the Cerro Porteno goalkeeper was still unable to keep it out as the 26-year-old scored his 10th goal of the qualifying campaign.
Di Maria was denied a second when he had a shot cleared off the line by Oscar Romero after exchanging passes with Messi on the hour-mark.
Romero kept out Nunez with a fine save as the tempo slowed but there was still time for Paraguay to score a consolation goal through Santa Cruz, who tapped in Samudio's cross in the 86th minute, while Rodriguez capped off the rout for Argentina when he scored four minutes later.
|P. da Silva|
|R. Santa Cruz||86'|
|Coach: V. Genes|
for R. Ortiz 21'
for S. Aquino 46'
for J. Fabbro 55'
|Klopp: Plenty left to play for|
|Premier League Preview: Swansea City v Aston Villa|
|Ranieri focused on securing second place|
|Premier League Preview: Manchester United v Norwich City|
|Seedorf: Team unity behind Milan improvement|
|Adams expecting raucous Old Trafford|
|J.League Preview: Second meet fourth as leaders face Forlan|
|Premier League Preview: Fulham v Hull City|
|Premier League Preview: Southampton v Everton|
|Ligue 1 Preview: PSG on brink of title, Valenciennes fight for survival|
|CSL Preview: Guangzhou look to build on momentum|
|Olic signs new Wolfsburg deal|
|Olic signs new Wolfsburg deal|
|K-League Preview: Struggling Incheon face leaders Pohang|
|Bundesliga Preview: Bayer Leverkusen v Borussia Dortmund|
|Suarez excited over Liverpool potential|
|Bundesliga Preview: Bayern Munich v Werder Bremen|
|Garcia has one eye on next season|
|CAF Confederation Cup Preview: Kaizer Chiefs in trouble, Al Ahly hold slender lead|
|Beck extends Hoffenheim stay|
|League Two Preview: Wycombe, Bristol Rovers in crunch relegation clash|
|UEFA bans for failing FFP unlikely - Platini|
|Coloccini: Current form not good enough|
|La Liga Preview: Barca seek to close on fatigued Atletico|
|We have underachieved, says Allardyce|
|Neymar ´genius´ will light up World Cup - Carlos|
|Milan deny sale rumours|
|Hughes eyes top-half finish|
|Ridgewell to miss next two games|
|Martinez keen to discuss Traore deal|
|Messi will shine in right ´climate´, Sabella insists|
|Suarez: We have surprised ourselves|
|Lucas thrilled to contribute in edgy PSG victory|
|Lahm rues lack of Bayern killer instinct|
|Sturridge boost massive for Liverpool - Henderson|
|Ronaldo in ´perfect´ condition|
|Lloris blasts Spurs|
|Copa Libertadores Wrap: Lanus advance|
|Klinsmann delighted for in-form Dempsey|
|Costa Rica Primera Division Wrap: UCR seal fourth spot|
|Sturridge hopeful of facing Chelsea|
|Liga MX Preview: Battle for play-off places continues|
|MLS Preview: Rimando on verge of record|
|CONCACAF Champions League: Toluca 1 Cruz Azul 1 (1-1 agg, Cruz Azul win on away goals)|
|MLS: New York Red Bulls 4 Houston Dynamo 0|
|Jesus excited by Juventus clash|
|Pizzi: Europa League semi a career highlight|
|A-League Preview: Wanderers welcome Mariners in semi-final|
|Ancelotti: Real survived without fit Bale, Ronaldo|
|Guardiola: Real ´unstoppable´ on the break|
|Ramos urges Real to be positive|
|Robben ´expected more´ from Real|
|UEFA Champions League: Real Madrid 1 Bayern Munich 0|
|Blanc hails match-winner Matuidi|
|Ligue 1 Wrap: PSG close in on title as Matuidi strike downs Evian|
|AFC Champions League Wrap: Sanfrecce Hiroshima, Bunyodkor leave it late to progress|
|Liverpool reveal Anfield expansion plans|
|Ligue 1: Paris Saint-Germain 1 Evian 0|
|Conte wary of fatigue factor|
|Januzaj opts to play for Belgium|
|Mourinho, Faria, Ramires charged by FA|
|Serie A Preview: Roma v Milan|
|Emery focused on first leg|
|Vorm endorses Van Gaal for United role|
|Hamann: Benitez would be a very good match for United|
|Verbeek reveals disappointment after Nuremberg axe|
|Dorrans can be the difference - Olsson|
|Hoger returns to Schalke training|
|Giggs not ready for United job, says May|
|Thauvin would welcome Bielsa arrival|
|Martinez will not rush Jagielka|
|Bremen to focus on developing young players|
|Brady hoping to win race against time|
|Alexis would take Juve to next level - Ravanelli|
|Champagne criticises ´polarisation´ of European football|
|Moyes breaks silence with dignified statement|
|Butland has learned plenty in Leeds stay|
|Bennett desperate for Norwich return|
|Icardi rumours inevitable, says agent|
|Championship Preview: Relegation likely for Yeovil Town, Barnsley|
|Moratti: Zanetti could have become Inter president|
|Giggs quick to ask for Scholes help|
|Giroud wants Arsenal stay, Wenger new deal|
|World Cup chance excites Ameobi|
|Barcelona transfer ban suspended|
|Rossi returns to training|
|Liverpool owners already planning for next season|
|Verbeek sacked by Nuremberg|
|League One Preview: Shrewsbury must win as relegation battle intensifies|
|Chelsea tie ´completely open´, says Filipe Luis|
|Title race will go to the wire - Pellegrini|
|Farina sacked by Sydney FC|
|Cech suffers dislocated shoulder|
|Ronaldo fitness will not be risked - Ancelotti|
|O´Farrell: Moyes sacking a growing trend|
|Serie A Preview: Juventus out to seal title, Roma host Milan|
|Leicester dominance unexpected, says Pearson|
|Copa Libertadores: Bolivar 1 Leon 1 (3-3 agg)|
|Bundesliga Preview: Nuremberg still fighting for survival|
|No regrets for Leonardo|
|Wilkins backs Ancelotti for United|
|Ayre: Champions League vital to attract stars|
|Mignolet: 30-goal Suarez ´amazing´|
|Giroud: I want to stay|
|Advantage Chelsea, says Simeone|
|Mourinho flags weakened Anfield line-up|
|Cech out for season, Terry facing fitness fight|
|Gabi: Chelsea draw leaves bad taste|
|Championship Wrap: Leicester crowned champions, Reading boost play-off hopes|
|Schwarzer praises determined Chelsea|
|UEFA Champions League: Atletico Madrid 0 Chelsea 0|
|AFC Champions League Wrap: Defending champions Guangzhou progress|
|I feel sorry for Moyes - Ancelotti|
|United players should be ashamed, says Keane|
|Valcke: Stadium will be ready for World Cup opener|
|UEFA Europa League Preview: Sevilla v Valencia|
|Pique defends Fabregas|
|Kehl out for two weeks with groin injury|
|McCartney wants new West Ham deal|
|Diaby set for Arsenal return|
|De Sciglio claims Real interest|
|Capoue returns to Tottenham training|
|Icardi wants to stay at Inter|
|Plenty of positives for Monreal|
|Mirallas out of Everton run-in|
|I want Ronaldo to play - Guardiola|
|Blanc expects Ibrahimovic return|
|Bodde in induced coma|
|Sagbo fined after admitting quenelle charge|
|Guardiola rules out United switch|
|UEFA Europa League Preview: Benfica v Juventus|
|AFC Wimbledon charged with fielding an ineligible player|
|Salvio undergoes surgery|
|McCarthy dreaming of Europe|
|Khedira may return before end of season|
|Ronaldo faces fitness test ahead of Bayern clash|
|Fryatt in Bruce´s plans|
|Bale back in Real training|
|Tonev ready to produce for Villa|
|Hard work ahead for Newcastle, says Pardew|
|Risse hails ´incredible feeling´ after promotion|
|Jones rues slow start|
|Blackstock hit with FA charge|
|No decision over Lyon future, says Garde|
|Giggs named interim United boss|
|Klopp ´committed to Dortmund´|
|Houllier backs Liverpool title bid|
|Marchisio expects difficult Benfica test|
|Gabi hoping Torres will not make return|
|Five low points of Moyes´ Manchester United reign|
|Davies expects Bony interest|
|United part company with Moyes|
|Top-half finish needed for Schuster, Malaga|
|Susic asks for Pjanic, Lulic to be released early|
|Mertesacker: Injuries hampered campaign|
|Sterling hails Rodgers|
|Capello to retire after 2018 World Cup|
|Paraguay Division Profesional Wrap: Libertad stay top with big win|
|Chile Primera Division Wrap: Relegation battle continues|
|Uruguay Primera Division Wrap: Penarol stay top|
|Argentina Primera Division Wrap: Gimnasia La Plata go top|
|La Liga: Malaga 2 Villarreal 0|
|Mel ready for ´cup final´|
|City have a ´duty´ to push for title, says Pellegrini|