Argentina have booked a place at the 2014 World Cup after a 5-2 win over Paraguay in Asuncion on Tuesday.
Alejandro Sabella's men were the dominant side at Estadio Defensores del Chaco, winning thanks to a brace of Lionel Messi penalties, plus goals from Sergio Aguero, Angel Di Maria and Maxi Rodriguez.
Argentina goalkeeper Sergio Romero's howler gifted an equaliser to Paraguay in the first half through Jose Nunez but Di Maria and Messi put the result beyond doubt shortly after the break as their side stayed top of CONMEBOL World Cup qualifying.
Roque Santa Cruz scored a late consolation goal for Paraguay, who cannot qualify for the World Cup.
Now seven points clear of fifth-placed Uruguay with two games remaining, Argentina join hosts Brazil as the two South American teams with a place booked at the 2014 tournament.
Argentina struck first on 12 minutes after a fast counter-attack led to Paraguay being exposed on the break.
It was a three-on-one break and Di Maria's pass found Aguero at the back post, with the Manchester City forward brought down by the advancing Roberto Fernandez.
Messi stepped up and placed his penalty into the bottom corner as Fernandez dived the wrong way, giving him his 36th goal for Argentina.
The goal sent the Barcelona star into clear second on the all-time leading goalscorers list for his country, ahead of Hernan Crespo (35) but still some way behind Gabriel Batistuta (56).
Argentina's lead only lasted five minutes before a howler from Romero gifted Paraguay their equaliser.
Nunez flicked Miguel Samudio's cross goal-ward and Romero should have dealt with the effort but it bounced over the diving goalkeeper and into the net.
Argentina should have restored their lead three minutes later, but – with an open goal to aim at – Inter striker Rodrigo Palacio put his header wide from close range.
Paraguay captain Santa Cruz was denied by Romero on the half-hour mark, with the goalkeeper tipping the Malaga striker's header over.
It was the combination between Messi and Aguero which led to the latter giving Argentina a 2-1 lead, just moments after another nervy moment by Romero when he dropped a cross.
Messi cushioned down a pass with his chest for Aguero, who took a touch before firing into the bottom corner with his left foot.
Argentina were being given far too much space in the attacking third and Messi had two strikes at goal saved by Fernandez before half-time.
Aguero thought he had given Argentina a two-goal lead on the stroke of half-time but he was correctly ruled offside.
If Paraguay held some hope heading into the second half, it was dashed inside eight minutes after the break.
Di Maria netted in a one-on-one with Fernandez after a lovely Fernando Gago pass before Messi scored from the penalty spot again.
It was a soft penalty awarded against Salustiano Candia for a foul on Messi but came after Paraguay were again left exposed and outnumbered at the back.
Messi chose the other way with his penalty – shooting to Fernandez's left – but the Cerro Porteno goalkeeper was still unable to keep it out as the 26-year-old scored his 10th goal of the qualifying campaign.
Di Maria was denied a second when he had a shot cleared off the line by Oscar Romero after exchanging passes with Messi on the hour-mark.
Romero kept out Nunez with a fine save as the tempo slowed but there was still time for Paraguay to score a consolation goal through Santa Cruz, who tapped in Samudio's cross in the 86th minute, while Rodriguez capped off the rout for Argentina when he scored four minutes later.
|P. da Silva|
|R. Santa Cruz||86'|
|Coach: V. Genes|
for R. Ortiz 21'
for S. Aquino 46'
for J. Fabbro 55'
|Rodgers expects new Gerrard deal|
|Jones: United embracing Van Gaal methods|
|Henry: Time had come to sell Suarez|
|Brunt eyes new West Brom deal|
|Arsenal´s World Cup winners to miss league opener|
|Modric hails Rodriguez, Kroos signings|
|Cech does not want bench role|
|Inzaghi blames fatigue for Milan loss|
|Real´s time to shine, says Ancelotti|
|Real Salt Lake 3 Montreal Impact 1: Garcia stars in Utah|
|Downing: Carroll injury a ´big blow´|
|Irvine: I have not seen Ideye play live|
|Olympiacos triumph in Toronto|
|Giggs likens Van Gaal to Ferguson|
|Copa do Brasil Review: Corinthians among trio on the verge of progression|
|Blanc: World Cup stars will move on|
|Pinto steps down as Costa Rica coach|
|Mourinho planning Drogba swoop|
|UEFA Europa League Review: Rosenborg complete comeback to see off Sligo|
|Mathieu out to enjoy Barcelona move|
|Mandzukic not Diego Costa´s replacement|
|Eliseu returns to Portugal with Benfica|
|Sanabria makes Roma switch|
|Carroll to miss start of season|
|Vidal: I´m not going to Manchester|
|Xavi staying at Barcelona|
|Hannover complete Gulselam signing|
|Astori loaned to Roma, Cagliari confirm|
|Nigeria to talk with Keshi over return|
|Gamberini makes Chievo move|
|Besic poised to complete Everton move|
|Marseille move Montpellier fixture from Stade Velodrome|
|CSL Preview: Harbin eye Luneng scalp, Guangzhou face Hena|
|Guardiola preaches patience with Lewandowski|
|Lampard joins New York City|
|Blanc coy on Di Maria speculation|
|CAF Confederation Cup Preview: ASEC coach confident, Al Ahly seek qualification|
|Chelsea loan Piazon to Frankfurt|
|Pochettino has high hopes for Lamela|
|Aguirre appointed as Japan coach|
|Swansea swoop for Montero|
|Pozuelo makes Vallecano switch|
|Fred back at Shakhtar, Ismaily to follow|
|CFF investigate Fofana accusations|
|Suarez could make sensational Clasico debut|
|Ribery in line for return, says Guardiola|
|Reus could resume training in two or three weeks - Klopp|
|Roma need another defender, says Garcia|
|Everton on verge of new signings|
|Rodrigo hails Nuno after Valencia switch|
|Delph eager for new Villa deal|
|Ljajic not seeking Roma exit|
|Talks held as players strike in Ecuador|
|Crouch excited by Bojan capture|
|Lambert expects swift recovery for Cole|
|West Ham duo fail to travel|
|United to play 3-4-3, says Van Gaal|
|Lallana, Markovic set to feature against Olympiacos|
|Real want to win every trophy, says Bale|
|San Jose Earthquakes 5 Chicago Fire 1: Hosts break winless streak|
|Chelsea have "outstanding squad" - Costa|
|United make winning start under Van Gaal|
|Rodgers plays down Borini injury concerns|
|Atletico Mineiro 4 Lanus 3 (agg 5-3): Own goals gift Brazilians the win|
|Dunga names Brazil assistants|
|Man City show class in Kansas|
|Villa too good for Dallas|
|Santos cannot meet Robinho´s demands, says vice-president|
|Mourinho happy with goalkeeper situation|
|Borini hurt as Liverpool lose to Roma|
|Palace held to draw by Crew|
|Tottenham down Toronto after Lamela brace|
|San Lorenzo 5 Bolivar 0: Hosts close in on Copa Libertadores final|
|Sunderland forward Scocco joins Newell´s|
|Rodgers: We won´t overpay in transfer market|
|Maccabi Haifa friendly abandoned after pitch invasion|
|USA dynamo Beasley joins Houston|
|UEFA Champions League Review: Steaua ease through as Legia Warsaw hit five|
|Youngsters inspire Sunderland to win at Hartlepool|
|Aluko and Sagbo net as Hull City beat York|
|PSG loan Aurier from Toulouse|
|Emotional Davies thanks Swansea fans|
|Mandzukic makes debut as Atletico win|
|Filipe makes bow in Chelsea draw|
|Bahebeck stars again as PSG beat Nice|
|Conte rubbishes PSG talk|
|Tottenham sign Davies and Vorm as Sigurdsson joins Swansea|
|De Laurentiis vows Napoli will fight for Scudetto|
|Lyon sign Jallet from PSG|
|Rijeka deny racism allegations|
|Suarez has been treated ´like a murderer´, says Aspas|
|Basel secure Samuel swoop|
|Thai Premier League Review: Buriram go top as Muang Thong slip up|
|Dnipro-Copenhagen clash moved to Kiev|
|Tevez never considered Juve exit|
|Djuricic joins Mainz on loan|
|Cavani keen on PSG stay|
|Shaqiri flattered by Juventus link|
|Johnson, Sommer arrive at Monchengladbach|
|J.League Review: Kawasaki close gap on Sagan, Urawa move clear at top|
|Coleman to miss Everton´s Thailand trip|
|Thankful Rueda bids farewell to Ecuador|
|Liga MX Preview: Peralta set for home debut, Leon seek recovery|
|K.League Review: Top two draw blanks, Jeju United close in|
|CAF Champions League Preview: Zamalek primed for crucial game, CS Sfaxien meet ES Tunis|
|Low quashes Germany exit rumours|
|Getafe agree Michel loan|
|Porto bring in Brahimi from Granada|
|Pardew satisfied with attacking signings|
|Pellegrini targets further City signings|
|Sevilla complete Krychowiak deal|
|Eisfeld makes Fulham move|
|Zarate opens account as West Ham stumble|
|I have nothing to prove, says Ince|
|Barcelona seal Mathieu deal|
|United prepared to spend big, claims Woodward|
|Shakhtar to play in Lviv|
|Pereyra poised for Juve switch|
|Fabregas eyes trophies at Chelsea|
|Vorm confirms Tottenham transfer|
|Deila: Forster will leave Celtic eventually|
|No pressure for Shaw|
|Van Gaal happy with preparations|
|Diarra aiming for Bordeaux return after West Ham frustration|
|Last season for Montpellier owner Nicollin|
|Monaco: Rodriguez deal too good to ignore|
|Nacional Asuncion 2 Defensor Sporting 0: Hosts surge towards Libertadores final|
|Garcia eyeing Serie A title|
|Father against Vlasic´s move abroad|
|Rodgers welcomes Gerrard´s international retirement|
|Cruzeiro, Atletico Mineiro bid for Robinho|
|Inzaghi not drawn into Balotelli speculation|
|Dunga ´not going to sell a dream´|
|City´s Fofana allegedly racially abused|
|Carroll ruled out of NZ friendlies|
|Rodgers excited by new arrivals|