Argentina have booked a place at the 2014 World Cup after a 5-2 win over Paraguay in Asuncion on Tuesday.
Alejandro Sabella's men were the dominant side at Estadio Defensores del Chaco, winning thanks to a brace of Lionel Messi penalties, plus goals from Sergio Aguero, Angel Di Maria and Maxi Rodriguez.
Argentina goalkeeper Sergio Romero's howler gifted an equaliser to Paraguay in the first half through Jose Nunez but Di Maria and Messi put the result beyond doubt shortly after the break as their side stayed top of CONMEBOL World Cup qualifying.
Roque Santa Cruz scored a late consolation goal for Paraguay, who cannot qualify for the World Cup.
Now seven points clear of fifth-placed Uruguay with two games remaining, Argentina join hosts Brazil as the two South American teams with a place booked at the 2014 tournament.
Argentina struck first on 12 minutes after a fast counter-attack led to Paraguay being exposed on the break.
It was a three-on-one break and Di Maria's pass found Aguero at the back post, with the Manchester City forward brought down by the advancing Roberto Fernandez.
Messi stepped up and placed his penalty into the bottom corner as Fernandez dived the wrong way, giving him his 36th goal for Argentina.
The goal sent the Barcelona star into clear second on the all-time leading goalscorers list for his country, ahead of Hernan Crespo (35) but still some way behind Gabriel Batistuta (56).
Argentina's lead only lasted five minutes before a howler from Romero gifted Paraguay their equaliser.
Nunez flicked Miguel Samudio's cross goal-ward and Romero should have dealt with the effort but it bounced over the diving goalkeeper and into the net.
Argentina should have restored their lead three minutes later, but – with an open goal to aim at – Inter striker Rodrigo Palacio put his header wide from close range.
Paraguay captain Santa Cruz was denied by Romero on the half-hour mark, with the goalkeeper tipping the Malaga striker's header over.
It was the combination between Messi and Aguero which led to the latter giving Argentina a 2-1 lead, just moments after another nervy moment by Romero when he dropped a cross.
Messi cushioned down a pass with his chest for Aguero, who took a touch before firing into the bottom corner with his left foot.
Argentina were being given far too much space in the attacking third and Messi had two strikes at goal saved by Fernandez before half-time.
Aguero thought he had given Argentina a two-goal lead on the stroke of half-time but he was correctly ruled offside.
If Paraguay held some hope heading into the second half, it was dashed inside eight minutes after the break.
Di Maria netted in a one-on-one with Fernandez after a lovely Fernando Gago pass before Messi scored from the penalty spot again.
It was a soft penalty awarded against Salustiano Candia for a foul on Messi but came after Paraguay were again left exposed and outnumbered at the back.
Messi chose the other way with his penalty – shooting to Fernandez's left – but the Cerro Porteno goalkeeper was still unable to keep it out as the 26-year-old scored his 10th goal of the qualifying campaign.
Di Maria was denied a second when he had a shot cleared off the line by Oscar Romero after exchanging passes with Messi on the hour-mark.
Romero kept out Nunez with a fine save as the tempo slowed but there was still time for Paraguay to score a consolation goal through Santa Cruz, who tapped in Samudio's cross in the 86th minute, while Rodriguez capped off the rout for Argentina when he scored four minutes later.
|P. da Silva|
|R. Santa Cruz||86'|
|Coach: V. Genes|
for R. Ortiz 21'
for S. Aquino 46'
for J. Fabbro 55'
|Perth Glory 3 Melbourne Victory 3: Leaders stage two-goal late comeback|
|Neymar: Barca have no interest in Real results|
|Milan defender Mexes apologises for red card|
|South Korea v Iraq: Strange lead-up for Shenaishil´s men|
|Lazio´s Djordjevic thanks well-wishers ahead of ankle surgery|
|Iran´s Asian Cup appeal dismissed by AFC|
|Cech urges Chelsea to clean up FA Cup exit ´mess´|
|Henderson: Liverpool are up for the cup|
|Edimar wants ´normal´ ban for Real star Ronaldo|
|Pellegrini defends misfiring City strikers|
|Australia ready for UAE - Sainsbury|
|Blanc takes positives from past|
|Inzaghi promises ´something different´ at Milan|
|Mexes sorry for seeing red|
|La Liga Review: Wins for top three|
|Vitoria Guimaraes 2 Gil Vicente 2: Last-gasp penalty salvages point for hosts|
|Simeone marvels at Griezmann impact|
|Djordjevic to have x-ray on ankle problem|
|Eredivisie Review: PSV go seven points clear, Heerenveen cruise|
|Luis Enrique backs himself on Suarez omission|
|Lazio 3 Milan 1: Parolo and Klose seal victory|
|Cameroon 1 Guinea 1: Draw ensures Group D stays finely poised|
|Rodgers reveals Sturridge fitness boost after Bolton stalemate|
|Atletico Madrid 3 Rayo Vallecano 1: Griezmann inspires routine win|
|Gabriel move agreed, Campbell to join Villarreal on loan|
|Gabon v Equatorial Guinea: Neighbours face off for quarter-final berth|
|FA Cup Review: Chelsea stunned by Bradford as Middlesbrough beat Manchester City|
|Ronaldo apologises for red card|
|Pulis eyes room for improvement|
|Liverpool 0 Bolton Wanderers 0: Championship side frustrate Anfield to earn replay|
|Karanka hails players after stunning City|
|Elche 0 Barcelona 6: Neymar and Messi inspire resounding win|
|League Two Review: Wycombe and Burton held, Shrewsbury up to second|
|Pardew lauds Palace performance|
|Pochettino laments late collapse|
|Scottish Premiership Review: Celtic stretch lead, Inverness and Dundee United keep up chase|
|Parkinson revels in huge upset after humbling Chelsea|
|Bayern targeting unbeaten Bundesliga season - Robben|
|Pearson: FA Cup win can breed confidence|
|League One Review: Dons close gap, Peterborough end run|
|Ivory Coast 1 Mali 1: Gradel rescues Renard´s men|
|Fulham seal Richards loan|
|Pellegrini: UAE trip had no impact|
|Koeman blames defeats on defensive lapses|
|Gundogan injury mars Dortmund preparations|
|Championship Review: Ighalo stars as Blackpool capitulate|
|Chelsea defeat a ´disgrace´ - Mourinho|
|Monk rues missed opportunity|
|Manchester City 0 Middlesbrough 2: Boro stun City with FA Cup shock|
|Chelsea 2 Bradford City 4: League One outfit dump out Premier League leaders|
|Tottenham 1 Leicester City 2: Late turnaround stuns Spurs|
|Cordoba 1 Real Madrid 2: Bale steals late win as Ronaldo sees red|
|Birmingham City 1 West Brom 2: Anichebe seals derby triumph|
|Southampton 2 Crystal Palace 3: Pardew´s men reach fifth round|
|Sunderland 0 Fulham 0: Defoe fails to fire on home debut|
|Bowyer hails ´terrific´ Blackburn|
|Rochdale v Stoke City: Shawcross in race to be fit for cup clash|
|Blackburn Rovers 3 Swansea City 1: Late goals snatch victory for Championship side|
|Congo v Burkina Faso: Le Roy vows to attack|
|Roma still in race for Scudetto - Garcia|
|Mancini coy on Toure links|
|Mertens rules out Napoli exit|
|Barzagli back in Juve squad|
|A-League Review: Adelaide and Sydney rack up the goals|
|Real have signed a ´diamond´ in Silva, says Oliveira|
|Queiroz: How can Williams sleep at night?|
|Asian Cup history ´the focus´ for Australia - Kruse|
|Pogba could be the world´s ´most expensive´ player|
|Australia international joins Dundee United|
|Real Madrid is a ´dream come true´ - Silva|
|Van Gaal angered by first-half showing in cup stalemate|
|Gourcuff laments ´cruel´ Gyan winner|
|UAE will head into semi-final with confidence, says Ali|
|Nice 2 Marseille 1: High-flyers downed on travels|
|St Johnstone 1 Aberdeen 1: Rooney earns title hopefuls a point|
|Cambridge United 0 Manchester United 0: Money´s men bag dream replay|
|Lucas Silva seals Real switch|
|Twente 2 Heracles 0: Strugglers left to rue Zomer error|
|Grant hails injury-time hero Gyan|
|South Africa 1 Senegal 1: Mbodji header denies Bafana Bafana|
|Red Star 2 Consolat Marseille 0: Allegro and Beziouen book Saint-Etienne tie|
|Parma deny Cassano legal action rumours|
|Ivory Coast v Mali: Renard demands more from captain Toure|
|Birthday boy Robben runs the show in five-goal Bayern romp|
|Saint-Etienne v Paris Saint-Germain: Blanc´s men look to reignite season|
|Ghana 1 Algeria 0: Gyan strikes at the last to boost quarter-final hopes|
|Juventus v Chievo: Llorente knows no let-up in title chase|
|Aston Villa v Bournemouth: Championship leaders in search of upset|
|Hughes rubbishes Bojan speculation|
|Brighton and Hove Albion v Arsenal: Wenger wary of attacking threat|
|Aguirre proud despite Asian Cup elimination|
|Bristol City v West Ham: Allardyce warns Premier League high flyers|
|Cameroon v Guinea: Mbia set for return|
|Inzaghi not fearful of the sack|
|Schalke sign teenager Sivodedov|
|Raiola plans to stand for FIFA presidency|
|Mourinho: Chelsea not planning to buy or sell in January|
|Queiroz praises battling Iran|
|Shenaishil lauds ´leader´ Mahmoud|
|Luis Enrique wary of Elche|
|Leeds confirm Cellino resignation|
|Japan 1 UAE 1 (aet, 4-5 pens): Stars cost champions´ progression|
|Pekerman: Falcao will come good|
|Allardyce awaiting Fletcher decision|
|Rodgers eager to keep Johnson and Lucas|
|Iran 3 Iraq 3 (aet, 6-7 pens): Shakir seals famous victory|
|Agent ´almost certain´ Ronaldo will retire at Real|
|Wenger calls for work permit changes|
|Lazio v Milan: Mauricio hopeful of debut|
|Inter v Torino: D´Ambrosio talks up Mancini impact|
|I was always confident - Benitez|
|Grant takes aim at AFCON organisers|
|Espanyol 3 Sevilla 1: Caicedo´s stunner sets up win|
|Rennes 1 Reims 1 (aet 5-4 on pens): Costil the the hero for last year´s runners-up|
|Napoli 2 Udinese 2 (aet 5-4 on pens): Holders edge through|