Burnley will be looking to extend their winning streak in the Championship to eight games when they visit Millwall on Saturday.
Sean Dyche's men have lost just one league game this season and boast a three-point lead at the top of the table.
They did suffer a 2-0 defeat to West Ham in the League Cup on Tuesday, but are still likely to be high on confidence as they take on a Millwall side who have not won in more than a month.
Leicester City are Burnley's nearest challengers and take on Watford at Vicarage Road in search of a fourth straight success in all competitions.
Nigel Pearson's men recorded a thrilling 4-3 victory over Fulham in midweek and are the only team from outside the Premier League in the last eight of the League Cup.
Watford, meanwhile, sit one place outside the play-offs and will be keen to bounce back from a first home loss of the season, at the hands of Derby County, last time out.
Derby, who have not lost since former England manager Steve McClaren took charge, travel to third-placed QPR.
The latter are a point behind Leicester in third but winless in three following a goalless draw with Wigan Athletic on Wednesday.
There is a meeting between fourth and sixth at Bloomfield Road, where Nottingham Forest will hope to get back on track after their surprise defeat to Yeovil Town by beating Blackpool.
Wigan host Huddersfield Town on Saturday, while Birmingham City, another side on midweek duty, welcome Charlton Athletic to St Andrew's.
Birmingham's League Cup campaign came to an end against Stoke City, but only after the Championship side had courageously fought back from 3-1 down with 10 men to take the tie to extra-time and, ultimately, a penalty shootout.
Bottom club Sheffield Wednesday will continue their search for a first win when Reading visit Hillsborough.
Fellow strugglers Barnsley and Yeovil each have away games, against Ipswich Town and Leeds United respectively.
Elsewhere, Brighton and Hove Albion face Doncaster Rovers and Blackburn Rovers play Middlesbrough.
|27||S. McDonald||23' 70'|
|Coach: S. Lomas|
|Ba left out of Senegal AFCON squad|
|Redknapp frustrated by penalty call|
|Wenger sees Giroud wrongs|
|Premier League schedule a ´disgrace´, says Poyet|
|Championship Review: Bournemouth stay top, Heskey scores on Bolton debut|
|Hughes lauds Bojan performance|
|Koeman: Saints marching on|
|Pardew rues referee error|
|Arsenal 2 QPR 1: Sublime Alexis secures the spoils|
|Martinez questions Walters decision|
|Poyet laments Sunderland mistakes|
|League One Review: Swindon cruise to win over Walsall|
|Irvine aware of need for improvement|
|United still doing ´very bad things´ - Van Gaal|
|Lambert proud of players despite Swansea defeat|
|Warnock bemoans Palace defence|
|Bruce hails Hull´s spirit|
|Pochettino relieved to come away with victory|
|Dyche: We had our pocket pinched|
|Monk hails Fabianski performance|
|Pearson demands greater concentration from Leicester|
|Kompany set for City return|
|Rodgers hails character after battling win|
|League Two Review: Ainsworth frustrated by Luton, Shrewsbury go top|
|Everton 0 Stoke City 1: Lacklustre Everton slip to defeat|
|Sunderland 1 Hull City 3: Triumphant return for Bruce|
|Burnley 0 Liverpool 1: Sterling wins it at Turf Moor|
|Leicester City 1 Tottenham 2: Eriksen piles misery on Pearson´s men|
|Manchester United 3 Newcastle United 1: Rooney extends hosts´ streak|
|West Brom 1 Manchester City 3: Three and easy for in-form champions|
|Swansea City 1 Aston Villa 0: Hosts break Boxing Day duck|
|Crystal Palace 1 Southampton 3: Mane marks return with star performance|
|Allardyce upbeat despite defeat|
|Van Dijk happy at Celtic - Deila|
|Table-topping Chelsea delight Mourinho|
|Chelsea 2 West Ham 0: Mourinho´s men ease to victory|
|Suarez enjoying Messi, Neymar link-up|
|A-League Review: Garcia rescues point for Perth, Adelaide up to second|
|Poyet calls for mid-season break|
|Van Gaal rules out Januzaj move|
|Rodgers: Balotelli may have to get used to bench|
|Lallana: I was trying too hard|
|Walker juggles music, football careers in Sweden|
|Song to face ´brother from another mother´ Fabregas|
|Adriano announces Le Havre deal|
|Pardew braced for Old Trafford test|
|Lescott unfazed by City reunion|
|Tskhadadze appointed Georgia coach|
|United to finish top three - Ferdinand|
|Allardyce: Stamford Bridge stalemate saved my job|
|Southampton need three January signings, says Watson|
|Liverpool can make Champions League, says fanzine editor|
|Walsh: Hull clash crucial for Leicester|
|Toure, Aubameyang and Enyeama make shortlist for African gong|
|Docherty backs Chelsea to win two-horse race|
|Liverpool could benefit from Hyypia influence - Scales|
|Saudi Arabia name Asian Cup squad|
|Forty-year-old Cahill no problem for Postecoglou|