Sao Paulo have progressed to the Copa Sudamericana quarter-finals after an extraordinary 5-4 aggregate win over Chile's Universidad Catolica.
The defending Copa Sudamericana champions were held at home to a 1-1 draw by Catolica in the first leg but fought back to win the second leg in Chile 4-3.
There was an early setback for the Brazilians with Ismael Sosa firing Catolica into a 16th-minute lead before Aloisio restored parity three minutes later.
It was the same circumstance in the 23rd minute as Fernando Cordero put Catolica back in front but the lead only lasted a minute as Aloisio secured his brace that evened the tie and gave Sao Paulo the away goals advantage.
The score remained 2-2 through half-time and early stages of the second period until Sao Paulo grabbed a stranglehold on the tie with Ademilson's 66th-minute goal.
Catolica did try to fight back into the contest and scored a third from the penalty spot through Milovan Mirosevic on 71 minutes but an 85th-minute goal from Welliton wrapped up proceedings for Sao Paulo.
Brazil's Bahia were eliminated 4-3 on penalties by Colombia's Atletico Nacional despite a 1-0 win at home in the second leg.
With the Colombians winning 1-0 in the first leg, penalties ensued after 90 minutes of the second leg with Souza and Fabricio Lusa missing for Bahia in the shootout.
Paraguay's Libertad had no trouble knocking out Brazilian Serie B club Sport Recife 4-1 on aggregate after a 2-1 win away from home.
After enjoying a comfortable 2-0 win in the first-leg, Libertad scored in the 42nd minute through Jorge Gonzalez and despite Ailson equalising on 47 minutes, the same Sport player put through his own net four minutes later to send the Paraguayans through.
In the other round-of -16 matches, Brazil's Ponte Preta advanced with a 2-1 aggregate win over Colombia's Deportivo Pasto despite a 1-0 loss on the road while Colombian side Itagui sealed progression 3-1 on aggregate over Brazil's Coritiba with a 2-1 win at home.
|10||M. Mirosevic||71' 88'|
|18||I. Sosa||16' 37'|
|Coach: M. Lasarte|
for M. Biskupovic 67'
for F. Meneses 83'
|Sampaoli thrilled with substitutes´ influence, applauds Peru|
|Martino rues Copa America date with former side Paraguay|
|Former Birmingham City player Thwaites among Tunisia victims|
|Chile 2 Peru 1: Zambrano´s red card helps hosts into Copa final|
|Thiago Silva: ´I didn´t even know the ball had hit my hand´|
|Ronaldinho set to sign for Antalyaspor|
|Jara ban reduced on appeal by one match|
|Hiddink leaves Netherlands post|
|Cresswell pens new five-year deal at West Ham|
|Koeman: No serious United bid for Schneiderlin|
|Barbados eliminated from World Cup qualifying after fielding ineligible player|
|Former Catania president admits buying matches|
|Jones agrees Manchester United deal|
|Argentina v Paraguay: Valdez hoping not to need another comeback|
|Milan seal Bertolacci signing|
|Cech grateful to Abramovich and Chelsea fans|
|UEFA Champions League Preview: Brotherly pride at stake as B36 play TNS|
|UEFA Europa League Preview: Tommasi set to aid La Fiorita qualifying bid|
|Cech leaves Chelsea to join Arsenal|
|Paulinho ends Spurs frustration with Guangzhou move|
|Sampdoria confirm Eto´o exit amid Antalyaspor talk|
|Garcia departs Espanyol ahead of expected Qatar move|
|Watford to delay Doyley decision|
|Schlupp agrees new Leicester deal|
|Schweinsteiger hints at Bayern stay amid United links|
|Bertolacci thrilled ahead of Milan move|
|Langerak leaves Dortmund for Stuttgart|
|Muniain extends Athletic contract|
|Youngsters to get chance on US tour - Van Gaal|
|La Liga chief hits out at Real Madrid over TV rights opposition|
|Villa confirm Wilkins as assistant manager|
|Dicks joins West Ham coaching staff|
|Heldt enters to jeers, exits to cheers|
|Paraguay pride has grown at Copa America - Aguilar|
|Van Gaal tight-lipped on De Gea|
|Bacca confirms Milan agreement|
|Weight of expectation on hosts Chile to benefit Peru - Gareca|
|MLS Review: Timbers thump Sounders thanks to Adi´s double|
|Dzeko ´would run to Roma´ - Pjanic|
|Peru won´t sit back - Sampaoli|
|Zenga: Cassano, Balotelli will not be joining Sampdoria|
|Victory to start A-League defence away to Adelaide|
|I want to play MLS ´at the peak of my career´ - Johannsson|
|Allegri: I like Isco and Oscar|
|CAF Champions League Review: Comeback kings Smouha go top of Group A|
|Pirlo in attendance for New York derby|
|No Bayern deal yet, states Costa|
|Jara handed three-game ban|
|Sunderland striker Defoe sets 20-goal target|
|Leicester offer condolences to Albrighton and family after Tunisia attack|
|Chile v Peru: Potential Jara sanction hangs over semi-final|
|Sweden U21 v Portugal U21: History beckons for Jorge´s men|
|Neville appointed Valencia number two|
|Work halted at Olympic Stadium after fatality|
|Ibrahimovic in the same league as Messi - Sacchi|
|Giggs: United want to add winners|
|Turan sets record straight over transfer talk|
|Low keen for new Germany leaders to emerge|
|Tunisia part company with Leekens|
|Evans: Sterling´s Anfield exit must be a done deal|
|FIFA audit chief urges Blatter to stick by decision|
|Hrubesch urges caution after Germany U21s humbled|
|Taarabt hits out at ´very bad manager´ Redknapp|
|Bruce: I´m lucky I wasn´t sacked after Hull relegation|
|Van Hooijdonk warns Van Gaal over Depay tactics|
|SPFL looking into winter break|
|MLS Review: Earthquakes win California Clasico, Vancouver claim top spot in West|
|Muto must toughen up to succeed at Mainz - Ficcadenti|
|Diaz: Paraguay refuse to lose|
|Tragedy strikes for Paraguay match-winner Gonzalez|
|Robinho rues substitution, wanted to take penalty|
|Dunga: Brazil squad hit by virus|
|Fiorentina make ´insane offer´ to Salah|
|Women´s World Cup Review: England reach maiden semi-final|
|Mexico 2 Costa Rica 2: Herrera´s men recover after half-time|
|ES Setif 1 USM Alger 2: African champions beaten|
|Paraguay 1 Brazil 1 (4-3 on penalties): History repeats as Dunga´s men bow out|