Juventus face a tough ask in their bid to win their first UEFA Champions League match of the season when they travel to Real Madrid on Wednesday.
In a meeting of two of the true giants of European football, Juventus will be desperate for a win that would keep them in second position in Group B.
Juve have been held to 1-1 and 2-2 draws against FC Copenhagen and Galatasaray respectively and will enter the fixture off the back of a disappointing 4-2 loss at Fiorentina on Sunday.
First-half goals from Carlos Tevez and Paul Pogba looked to have Antonio Conte's side cruising, but Fiorentina – who were inspired by a hat-trick from Giuseppe Rossi – scored four times in the last 25 minutes to inflict Juve's first defeat of the season.
Conte hopes his side can respond quickly and denied claims that they were focusing on Real Madrid in the build-up to their trip to Florence.
"We lost a game that we dominated for 70 minutes. We were home and dry and had more than one opportunity to score the third goal," Conte said after the defeat.
"I don't think our focus was already on Real Madrid, otherwise we would have got our overall approach wrong."
Defender Stephan Lichtsteiner (thigh) and midfielder Simone Pepe (thigh) have been ruled out of the fixture.
And Juventus' injury worries do not stop there, with strikers Mirko Vucinic and Fabio Quagliarella (both thigh) also set to miss out.
Nine-time winners Real Madrid have won both of their Champions League fixtures this season, thrashing Galatasaray 6-1 before easing past FC Copenhagen 4-0.
Cristiano Ronaldo has scored five goals in those two matches, making him the competition's leading scorer.
The Portuguese star – who was top scorer last season with 12 goals – has now scored 24 goals in his last 20 Champions League appearances.
Ronaldo's 56 career strikes in the competition also see him fourth in the all-time scorers list.
World-record signing Gareth Bale has made just four appearances for Real since joining from Tottenham but returned from a thigh injury in the club's 2-0 win over Malaga on Saturday.
He is expected to feature against Juventus, while midfielder Xabi Alonso has returned to training following a broken foot.
The match will come too soon for Alonso but the news of his return will be a significant boost for Real, who can move a step closer to qualification for the Round of 16 with another victory.
|22||Á. di María|
|7||Cristiano Ronaldo||4' 29'|
|Coach: C. Ancelotti|
for K. Benzema 67'
for Illarramendi 72'
for Á. di María 79'
|Walcott happy to move on from Arsenal struggles|
|Champions League Matchday Two: Bayern hunt Atleti revenge|
|Coquelin facing three weeks out|
|Arsenal transfers beyond reproach, says Wenger|
|Schubert extends Gladbach contract|
|Lewandowski urges Bayern to learn from Atletico defeat|
|Griezmann feared Simeone to PSG was ´a done deal´|
|FA investigating Allardyce claims|
|Valencia keep Voro in charge for Atletico clash|
|One of Serie A´s all-time greats: The numbers behind Totti at 40|
|Toure brands FIFA ´complacent´ after racism taskforce closed|
|Emery expects Ronaldo to stay at Real Madrid|
|Tottenham not scared of Moscow trip - Alderweireld|
|Sessegnon signs with Montpellier|
|Rakitic delighted with form|
|Gameiro: I could have joined Barcelona|
|Stones talks up Celtic quality|
|Liverpool good enough to win title - Houllier|
|Klopp happy with Firmino in central role|
|Watford got bullied all over the pitch - Deeney|
|Nuno keen for Porto to end England misery|
|Legia boss Magiera set for whirlwind debut|
|´Terrific´ Burnley delight Dyche|
|Burnley 2 Watford 0: Landmark goals for Hendrick and Keane seal first win in four|
|Schmidt lauds hitman Hernandez|
|Klopp not banking on Liverpool winning title|
|Kroos plays down Ronaldo rage rumours|
|Confidence coursing through Copenhagen|
|Madrid form draws no concern for Zidane|
|Burki looking forward to ´dream´ Madrid clash|
|Juve and Higuain have work to do - Allegri|
|CSKA boss Slutski wary of Tottenham threat|
|Pochettino: Kane to return within three weeks|
|City youngster Diaz signs three-year deal|
|Aurier vows to ´continue working hard´ for PSG despite prison sentence|
|Tuchel expecting Ronaldo on top form|
|Ter Stegen eyes new Barcelona deal|
|Hazard: No excuse for Arsenal defeat|
|Cisse back in training with Auxerre|
|Hummels resumes training ahead of Atletico clash|
|Facing Barcelona´s MSN not a nightmare, insists Bravo|
|Thiago: Atletico defence best in the world|
|Alonso wants to end career at Bayern Munich|
|Ranieri went to Slimani for Porto advice|
|Draxler: Wolfsburg blocked my exit|
|Samoura defends abolishment of racism task force|
|Sampaoli backs Nasri for France recall|
|Gisdol ´twitching with joy´ at Hamburg presentation|
|Zanetti determined Inter will return to the top|
|Getafe sack Esnaider|
|Bartra happy with playing time at Dortmund|
|Aurier handed two-month prison sentence over police altercation|
|Klopp attributes Lallana´s fine form to hard work|
|Totti´s wife slams ´small man´ Spalletti|
|Guardiola has already done an amazing job at Manchester City - Alonso|
|Referees attacked by hooligans in Bosnia and Herzegovina|
|Griezmann: I am not the anti-Benzema|
|Sterling hails Guardiola´s role in goalscoring form|
|Champions League Matchday Two: Madrid look for first win in Dortmund|
|Smalling confident Rooney will bounce back|
|Vardy fears ´permanent stain against my name´ following casino incident|
|Brave Wilshere will reap rewards of loan move - Howe|
|MLS Review: Sounders surprise Galaxy, Kamara double sinks New England|
|Walcott a special case - Wenger|
|Guardiola striving for more after perfect 10|
|Chelsea risk another mid-table finish, admits Conte|
|Montella feels AC Milan lacked courage|
|Robben speaks out on injury fears|
|Fiorentina 0 AC Milan 0: Ilicic misses penalty on Montella´s return|
|Gisdol replaces Labbadia at Hamburg|
|Ibrahimovic threatened me over Pogba deal - Raiola|
|Balotelli could make Nice return against Krasnodar|
|Southampton deserved to win – Bilic|
|Podolski takes aim at Mourinho over Schweinsteiger treatment|
|Atletico midfielder Augusto suffers ACL injury|
|Sagna: More to Aguero than goals|
|Errors are urgent matter for Schalke - Weinzierl|
|Puel delighted with sublime Southampton second half|
|Simeone praises ´decisive´ Gameiro|
|Noble: West Ham can´t get any worse|
|Pjanic: I will play wherever Allegri needs me|
|West Ham 0 Southampton 3: Defensive woes pile pressure on Bilic|
|Kondogbia makes the same mistakes often – De Boer|
|Gray backed by Dyche after ban for abusive social media posts|
|Gabriel needs time to get used to Serie A - Ausilio|
|Atletico Madrid´s Gimenez and Augusto doubts for Bayern Munich clash|
|Atletico Madrid 1 Deportivo La Coruna 0: Griezmann downs 10-man Depor|
|Angry Spalletti slams Roma players´ attitude|
|Liverpool have unbelievable quality - Milner|
|Simeone´s son Giovanni scores first Serie A goal|
|Ivanovic: Chelsea let Conte down|
|Inter 1 Bologna 1: Battling Bologna end Inter streak|
|Guardiola: Top-four finish very tough for Man City|
|Rodgers expecting tough test against City and Aguero|
|Zamparini admits Balotelli interested Palermo|
|Former Swansea, Arsenal great Mel Charles dies|
|Asamoah, Rugani ruled out for up to seven weeks|
|Totti reaches 250 Serie A goals in Roma defeat|
|Alves makes LaLiga history as Valencia see off Leganes|
|Guardiola rues De Bruyne injury as Man City await scan|
|Las Palmas draw could prove costly, admits Morata|
|Gabriel explains choosing Inter over Juventus|
|Hamburg dismiss Labbadia|
|West Ham players expect Payet´s free-kick magic - Antonio|
|Man City must tell Guardiola to stop, says Toure´s agent|
|Hamsik thrilled to reach 100 Napoli goals|
|Zabaleta warns Man City over Celtic backlash|
|MLS Review: Red Bulls, Toronto into play-offs|
|´We were unlucky´ - Bale|
|Guardiola keen for Spurs test|
|Rodgers: I never fell out with Sterling|
|Wenger hails ´different´ Walcott|
|Mazzarri backs Deeney for England call-up|
|Mamelodi Sundowns and Zamalek reach CAF Champions League final|