Cruzeiro slumped to their third loss in four Brazil Serie A matches on Sunday but their nearest rivals failed to capitalise.
Despite being beaten 2-1 at Coritiba, the league leaders sit nine points clear at the top after the three teams below them failed to win.
Gremio and Botafogo both drew and third-placed Atletico Paranaense were well-beaten at Goias.
The loss continued a worrying run of form for Cruzeiro, who are in control at the top with eight league matches remaining.
Carlinhos gave Coritiba a 42nd-minute lead but his opener was cancelled out by Dagoberto from the penalty spot just after the hour-mark.
But Coritiba moved four points clear of the relegation zone thanks to Keirrison, who scored the winner in the 73rd minute.
Second-placed Gremio were unable to take advantage as they were held to a 2-2 draw at Internacional.
Andres D'Alessandro's 61st-minute penalty helped Internacional collect a point after Eduardo Vargas put Gremio ahead early in the second half.
Atletico Paranaense were never in the contest at Goias as they suffered a 3-0 loss, with the hosts scoring twice in the opening 27 minutes.
Roni and Dudu Cearense put Goias in complete control of the encounter before Walter sealed the win in the dying stages.
Fourth-placed Botafogo failed to hold onto their early lead at home to Vasco da Gama as they played out a 2-2 draw.
Dankler and Nicolas Lodeiro struck in the opening seven minutes for the hosts but Jomar and Pedro Ken's second-half goals saw relegation-threatened Vasco earn a point.
While Vasco are three points from safety, Criciuma are four adrift after a 1-0 loss at Corinthians and Ponte Preta a further two behind them despite drawing 1-1 at Fluminense.
Bottom side Nautico suffered their fifth straight loss as they were thrashed 5-1 at home to eighth-placed Santos.
Santos only needed 27 minutes to end Nautico's chances of getting anything out of the game, finding the net four times.
Sao Paulo held on for a 1-0 win at Bahia despite being reduced to nine men and Atletico Mineiro edged Flamengo 1-0.
Elsewhere, Portuguesa and Vitoria played out a 1-1 draw.
|Coach: Péricles Chamusca|
for Julio Cesar 66'
for Alex 71'
for Geraldo 84'
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