Mexico head coach Victor Manuel Vucetich believes Friday's clash with Panama will be 'the biggest game' of his life.
Vucetich was made Mexico's head coach last month as a replacement for Jose Manuel de la Torre, who was sacked after the Mexicans' 2-1 loss at home to Honduras on September 6.
The World Cup qualifier against Panama in Mexico City on Friday will be Vucetich's first in charge of the home side and with qualification effectively on the line, the 58-year-old knows how important the game will be.
"Right now, yes, this is going to be the biggest game of my life," Vucetich said.
"Definitely because of everything that we are playing for.
"We know what this game means and the commitment we're taking on.
"I've taken on this challenge knowing everything that is riding on this game and I trust in each and every one of the players because I know the majority of them and have seen them play over the years."
Mexico sit fifth in CONCACAF's standings with eight points in the confederation's fourth and final stage of qualifying with just two matches remaining.
The top three teams in CONCACAF's fourth round will qualify automatically for Brazil 2014 with the United States (16 points), Costa Rica (15) and Honduras (11) holding those spots heading into Friday's qualifiers.
The fourth team, which is currently Panama (eight points), will play a two-legged play-off with New Zealand for a spot at next year's World Cup finals.
If Mexico lose to Panama and Honduras claim at least a point against Costa Rica, Vucetich's team will be unable to qualify automatically for the World Cup but the coach is confident his side is ready to go on Friday.
"I know what we've been working on these last 10 or 11 days and I feel very calm and good about what we've achieved and about the commitment that the team has taken on from a sporting perspective towards the game," Vucetich said.
"I think the team has worked very well with a great attitude and we know what there is to do."
If Vucetich's side lose, Mexico will need to win away to Costa Rica on the final matchday, while they will also need the USA to overcome Panama and have a better goal difference than the Panamanians to reach the intercontinental play-off against New Zealand.
|O. Peralta||40' 60'|
|G. dos Santos|
|Coach: M. Vucetich|
for J. Aquino 65'
for G. dos Santos 70'
for J. Zavala 82'
|Mourinho tells Ronaldo: Team honours come first|
|Khedira returns to Juve training|
|Celtic v Qarabag: Champions League return of utmost importance, says Collins|
|Pellegrini: Jovetic had to go|
|Manquillo completes Marseille move|
|Schalke reject Juve´s Draxler bid|
|Blanc: Di Maria deal ´close´|
|Di Santo debut ends in stalemate|
|Fire sign Drogba, trade him to Montreal Impact|
|FIFA and UEFA welcome ruling on third-party ownership|
|Juve kick off title defence against Udinese|
|Stoke sign free agent Afellay|
|Benitez confident Ramos will stay|
|Fenerbahce issue warning to fans|
|UEFA Champions League Preview: De Boer confident Ajax are ready for Vienna test|
|Bility: I am the favourite for FIFA presidency|
|Pienaar to miss start of season|
|Vietnam 1 Manchester City 8: Sterling shines as tourists run riot|
|All-Star Keane relishing Spurs clash|
|Shaun Wright-Phillips joins brother Bradley at Red Bulls|
|Inter 0 Real Madrid 3: Rodriguez stunner caps comfortable win|
|Villa sign Ayew|
|Watford complete Berghuis transfer|
|Robben returns to Bayern training|
|Pulis anxious to make West Brom additions|
|David Luiz eager to welcome ´fantastic´ Di Maria|
|Fernando injury free ahead of new campaign|
|Hummels blames weight issues for poor season|
|Defoe hoping for early Sunderland goals|
|Depay hints at identity of ´surprise´ United striker|
|Tigres UANL v River Plate: Hosts look to bounce back and make history|
|Crespo set for Villa move|
|Terry: I would never join a Premier League rival|
|Van Gaal coy on United future|
|Romero to cover potential De Gea exit - Van Gaal|
|Uruguay win men´s football gold at Pan Am Games|
|Pirlo thanks New York City fans for ´beautiful´ welcome|
|Mexico capitalised on ´the mistakes we made´ - Schafer|
|Herrera delighted with Mexico display|
|MLS Review: Whitecaps build happy home, Pirlo debuts|
|Guardado wins Golden Ball at Gold Cup|
|NZF confirms Olympics disqualification appeal|
|Jamaica 1 Mexico 3: CONCACAF giants complete form turnaround|
|New York Red Bulls 2 Benfica 1: Another scalp for MLS side|
|Romero signs with United|
|Moghreb Tetouan 1 Al Hilal Omdurman 1: Visitors go top|
|Van Gaal rules out Ronaldo bid|
|Pique open to Barca captaincy|
|Pirlo makes MLS bow in thrilling NYC victory|
|Coutinho and Can return for Liverpool U21s|
|Walcott deal ´closer´, says Wenger|
|Arsenal 1 Wolfsburg 0: Walcott the match-winner in Emirates Cup finale|
|Di Santo links up with Schalke squad|
|Lukaku treble sinks Hearts|
|Benitez again refutes Ronaldo rift rumours|
|Pepe sure Ramos will stay at Real|
|City target De Bruyne named Germany´s Player of the Year|
|Montero spoils McCarthy´s Palace debut|
|Lyon 0 Villarreal 2: Soriano, Baptistao seal comfortable win in Emirates Cup|
|Wijnaldum on target as Newcastle are held|
|Mourinho: Rivals trying to buy the title|
|Jovetic set for Inter medical|
|RFS in ´denial´ over racism issue, claims Football Against Racism in Europe|
|Salah not staying at Chelsea - Mourinho|
|Mbemba closes in on Newcastle switch|
|Ibrahimovic: Di Maria will take PSG to another level|
|Delph: Don´t compare me to Pogba|
|Dundee United sign Sneijder|
|Morata relishing new-look Juve strikeforce|
|Strachan "not scared" of England after World Cup qualifying draw|
|Brazil claim football, basketball, handball gold in Toronto|
|Lampard´s debut delayed again, Pirlo ready to play|
|Mourinho open to Premier League matches in US|
|MLS Review: Texas unites to hurt Galaxy|
|Luis Enrique: United can emulate Barca revival|
|Van Gaal singles out Januzaj, hails United´s forwards|
|Blanc still hopeful PSG will sign Di Maria|
|Irish international Cunningham seeks Bristol City exit|
|Italy embracing Spain challenge in World Cup qualifying|
|Dos Santos brothers in doubt for Gold Cup final|
|PSG 1 Chelsea 1 (aet, 5-6 on penalties): Courtois clinches victory for Mourinho´s men|
|United States 1 Panama 1 (aet, 2-3 on penalties): Mejia denies hosts third|
|ES Setif 1 Al Merreikh 1: Sudanese deny title-holders at home|
|CONCACAF admit referee errors in Gold Cup semi-final|
|Dutch favourites in Group A - Deschamps|
|Barcelona 1 Manchester United 3: Rooney, Lingard and Januzaj maintain winning start|