Ten-man Borussia Dortmund lost for the first time in the league this season on Saturday after going down 2-0 at Borussia Monchengladbach.
Mats Hummels was sent off 10 minutes from time for a professional foul on Havard Nordtveit inside the area to concede a penalty that changed the complexion of the game.
Max Kruse put the hosts ahead from the resulting spot-kick before Raffael added a second in the 86th minute to seal Monchengladbach's first Bundesliga win against Dortmund since April 2011.
Goalkeeper Marc-Andre ter Stegen had earlier denied Dortmund, who struck the crossbar in between goals from Kruse and Raffael, with a string of fine saves as Monchengladbach executed an excellent late smash and grab.
Monchengladbach coach Lucien Favre named just one change from last weekend's 2-2 drew at Augsburg, with Granit Xhaka replacing Christoph Kramer.
Jurgen Klopp also made one alteration from the side that beat Marseille 3-0 in the UEFA Champions League on Tuesday, Roman Weidenfeller returning in goal in place of Mitchell Langerak.
Dortmund were the first to threaten in the fifth minute, Marco Reus curling his effort narrowly over the bar after latching on to a loose ball inside the area.
Ten minutes later the visitors were denied by a superb save from Ter Stegen, who thwarted Hummels from six yards after parrying Kevin Grosskreutz's long-range effort.
Klopp's men were making all the running in the opening stages and Ter Stegen was called into action once more in the 23rd minute, palming away Grosskreutz's stinging shot from 25 yards.
Dortmund went close again five minutes later, Reus sliding in Pierre-Emerick Aubameyang, but his left-footed effort from a tight angle flashed just wide of the post.
Reus then drove into the box in the 33rd minute, but the Germany international dragged his shot a yard wide of Ter Stegen's right-hand upright.
Five minutes before the break, Nuri Sahin's powerful drive was beaten away by the keeper as it remained scoreless at half-time.
The opening stages of the second half were much more even and the hosts should have taken the lead on the hour mark, but Oscar Wendt fired wide from 15 yards after good work by Kruse down the left.
Two minutes later, Ter Stegen was called into serious action for the first time since the break, tipping Reus' vicious dipping effort over the bar.
The visitors were suddenly looking dangerous once again, Hummels heading wide from Reus' right-wing corner midway through the half.
With 10 minutes to go, however, Kruse gave Monchengladbach the lead from the spot, sending Weidenfeller the wrong way after Hummels saw red for a professional foul on Nordtveit.
Dortmund almost responded immediately, Reus striking the bar with a free-kick, before Raffael put the game beyond doubt, stroking the ball past Weidenfeller after being played in on the right-hand side.
|1||M. ter Stegen|
|Coach: L. Favre|
for Álvaro Domínguez 56'
for P. Herrmann 77'
for H. Nordtveit 83'
|Barca felt Messi absence - Busquets|
|Martino knew Messi would come out of retirement|
|Shilton never convinced by Allardyce|
|Degenek replaced by Giannou for Socceroos|
|Griezmann will still take penalties - Simeone|
|Simeone proud of ´one of the best´ wins|
|Godin suffers sprained ankle ligament|
|West Ham receive positive news over injured duo|
|Robson: Four wins for Southgate and he´s an England contender|
|Gunes rues Besiktas´ inability to see off Dynamo|
|Sarri: Late goals leave bitter taste|
|Borussia Monchengladbach were exceptional against Barcelona, feels Schubert|
|PSG must be patient, says Emery|
|Celtic are lucky to have Dembele - Rodgers|
|I´m completely focused on Arsenal, insists Wenger amid England talk|
|Hasselbaink denies wrongdoing amid impropriety allegations|
|Ancelotti frustrated by slow, toothless Bayern|
|Barcelona deserved their win - Luis Enrique|
|I want Celtic atmosphere at City – Guardiola|
|Rebrov defends Yarmolenko after ´difficult´ match|
|Rostov draw is two points dropped for PSV, says De Jong|
|Torres eyeing ´magical´ year for Atletico|
|Celtic 3 Manchester City 3: Dembele at the double in six-goal thriller|
|Celtic 3 Manchester City 3: Dembele at the double in six-goal thriller|
|Rostov 2 PSV 2: Propper´s penalty miss costs visitors|
|Besiktas 1 Dynamo Kiev 1: Tsygankov stuns wasteful Turks|
|Napoli 4 Benfica 2: Mertens bags two as Napoli run riot|
|Arsenal 2 Basel 0: Walcott´s capital gains tax Swiss visitors|
|Borussia Monchengladbach 1 Barcelona 2: Pique grabs the winner|
|Atletico Madrid 1 Bayern Munich 0: Carrasco gives Ancelotti first taste of defeat|
|Ludogorets 1 Paris Saint-Germain 3: Cavani inspires comeback win|
|Premier League, FA and EFL to investigate transfer allegations|
|Vardy reveals matchday energy drink and port routine|
|Everton coping without Stones, says Jagielka|
|Sacked Jemez admits to ´great sadness´ at Granada exit after worst start in over 70 years|
|Wenger has so much to offer English football - Schmeichel|
|No truth to England rumours, says Klinsmann|
|Spalletti demands end to damaging Roma ´games´|
|De Boer: Brozovic was punished and forgiven|
|Allardyce paid price for lack of privacy - McClaren|
|Milik can match Lewandowski - Reina|
|LMA ´extremely concerned´ about manager bribe allegations|
|Iwobi: I nearly left Arsenal|
|Mata has found a ´natural habitat´ at United|
|Higuain slowly approaching top form|
|´Stupid´ Allardyce driven by money - Dyke|
|Wijnaldum vows to improve|
|Renato Sanches needs time at Bayern - Hitzfeld|
|Ibrahimovic nurturing United talent - Lingard|
|Mourinho feels sorry for Allardyce|
|United boss primed for ´must-win´ Europa League tie|
|Mourinho keen to protect under-fire Rooney|
|Jeonbuk Motors 4 Seoul 1: Leonardo brace puts hosts in the driving seat|
|Maloney returns to Scotland squad|
|Van Persie: Kids will decide my future|
|Entrapment won on this occasion - Allardyce|
|Ibra-Rashford pairing the answer for United - Neville|
|Tevez hints at imminent retirement|
|England in safe hands with Southgate - Glenn|
|Holman talks up A-League quality|
|CONCACAF Champions League Review: Red Bulls progress, Timbers win|
|Januzaj blow for Sunderland|
|Navas accepts blame for Dortmund equaliser|
|Sporting assistant Raul Jose pleased with win|
|Nuno left to regret slow start as Porto fail on English soil again|
|Vardy rejected Arsenal due to style|
|Simeone: I am not Griezmann´s mentor|
|Schmidt bemoans ´brutal´ Monaco equaliser|
|Ranieri doesn´t trust bookies over England job|
|Genesio worried wastefulness will cost Lyon in long run|
|Preud´homme admits Champions League too much for Club Brugge|
|Telegraph passes findings to FA after further corruption claims|
|Zidane: Draw difficult to accept|
|Pochettino delighted with in-form Son|
|Vietto undeterred by wasteful showing|
|Tuchel: Dortmund can still get better|
|Resilient Leicester display pleases Morgan|
|Glenn reflects on ´painful´ call to dismiss ´distraught´ Allardyce|
|Borussia Dortmund 2 Real Madrid 2: Late Schurrle strike salvages draw|
|Monaco 1 Bayer Leverkusen 1: Glik stunner snatches a point|
|Dinamo Zagreb 0 Juventus 4: Pjanic pilots comfortable victory|
|CSKA Moscow 0 Tottenham 1: In-form Son hits late winner|
|Copenhagen 4 Club Brugge 0: Delaney stunner helps Danish champions canter to victory|
|Sporting CP 2 Legia Warsaw 0: Magiera´s first game ends in defeat|
|Sevilla 1 Lyon 0: Ben Yedder seals win for Europa League holders|
|Leicester City 1 Porto 0: Slimani continues to haunt old foes|
|Shearer: Allardyce has made England a laughing stock|
|Howe, Pardew and Wenger among the contenders to succeed Allardyce|
|Emery´s PSG struggles give Ludogorets hope|
|Allardyce offers ´wholehearted apology´ for England shame|
|Lahm: ´Extraordinary´ Griezmann different to Lewandowski|
|Iniesta is the best in the world, claims Menotti|
|Irregular heartbeat ends Dempsey´s season|
|Bournemouth ´realistic´ over permanent deal for Wilshere|
|Guardiola warns against complacency|
|Allardyce and England part company after damning video|
|De Bruyne out for up to three weeks - Guardiola|
|Luis Enrique demands fast start at Gladbach|
|Ancelotti wary of Atletico threat|
|Al Ain 3 El Jaish 1: Caio capitalises on late error|
|Ter Stegen happy with solution to Bravo battle|
|Emery: PSG need time to gel|
|Hernandez: It was very difficult at Real Madrid|
|Derby stand down Pearson ahead of Cardiff match|
|Rodgers sympathises with ´poor guy´ Allardyce|
|Opponents are trying to get Ribery send off - Hoeness|
|Martino named Atlanta United head coach|
|Rodgers urges Celtic to have belief against City|
|Rodgers has made same impact as Guardiola - Brown|
|Benfica one of the best in Europe, warns Sarri|
|Menotti: Ronaldo never played in a team like Messi´s|
|Walcott happy to move on from Arsenal struggles|
|Champions League Matchday Two: Bayern hunt Atleti revenge|
|Coquelin facing three weeks out|
|Arsenal transfers beyond reproach, says Wenger|
|Schubert extends Gladbach contract|
|Lewandowski urges Bayern to learn from Atletico defeat|
|Griezmann feared Simeone to PSG was ´a done deal´|
|FA investigating Allardyce claims|
|Valencia keep Voro in charge for Atletico clash|
|One of Serie A´s all-time greats: The numbers behind Totti at 40|
|Toure brands FIFA ´complacent´ after racism taskforce closed|
|Emery expects Ronaldo to stay at Real Madrid|
|Tottenham not scared of Moscow trip - Alderweireld|
|Sessegnon signs with Montpellier|
|Rakitic delighted with form|
|Gameiro: I could have joined Barcelona|
|Stones talks up Celtic quality|
|Liverpool good enough to win title - Houllier|
|Klopp happy with Firmino in central role|
|Watford got bullied all over the pitch - Deeney|
|Nuno keen for Porto to end England misery|
|Legia boss Magiera set for whirlwind debut|
|´Terrific´ Burnley delight Dyche|