Mauricio Pochettino knows he will need to manage his Southampton squad carefully to keep his players fresh.
Southampton fell to a 2-0 loss against leaders Arsenal on Saturday but were without the services of influential centre-back Dejan Lovren, while England international Adam Lallana and young full-back Luke Shaw were both substituted at the Emirates Stadium.
Pochettino explained that Lovren's absence was due to an illness from which he is expected to make a swift recovery, while Shaw suffered a first-half impact injury.
"Dejan Lovren had a really bad night and stayed back in Southampton," said Pochettino. "Hopefully he's going to be back in fit, 100 per cent for Monday.
"Also we'll need to analyse how Luke Shaw is doing because in the first half he received a very strong knock on his leg.
"Hopefully the two of them will be back and ready for Monday."
Lallana started both England games during the international break, earning his first two caps, and Pochettino felt he needed a rest.
"Adam played two games for the national side and after that he was struggling a little bit physically," he added.
"There was a certain moment in the game against Chile where he opened up his legs and I think that caused him some pain and today that was causing him some pain.
"There are many games coming up and we have to be careful over how we use our players - not just him but all our players.
"We have to be careful how we manage the amount of games we have ahead of us."
|12||O. Giroud||22' 86'|
|Coach: A. Wenger|
for Cazorla 70'
for Arteta 74'
for M. Özil 81'
|Putin: Blatter deserves a Nobel prize|
|Howe: Swansea a benchmark for Bournemouth|
|New Parma to play in Serie D|
|Mata vows to hit the goal trail at United|
|Drogba ´perfect fit´ for Montreal|
|Berahino ´not yet´ ready for Tottenham - Irvine|
|Romero lauds caring Van Gaal|
|Jese flying at Real under Rafa|
|Sampdoria unwilling to pay €10m for Balotelli|
|Mourinho talks up Arsenal title chances|
|Hull sign Ryan Taylor, Sam Clucas|
|Kane, Pochettino hail MLS All-Star test|
|Di Santo sorry for swift Werder departure|
|Mourinho tells Ronaldo: Team honours come first|
|Khedira returns to Juve training|
|Celtic v Qarabag: Champions League return of utmost importance, says Collins|
|Pellegrini: Jovetic had to go|
|Manquillo completes Marseille move|
|Schalke reject Juve´s Draxler bid|
|Blanc: Di Maria deal ´close´|
|Di Santo debut ends in stalemate|
|Fire sign Drogba, trade him to Montreal Impact|
|FIFA and UEFA welcome ruling on third-party ownership|
|Juve kick off title defence against Udinese|
|Stoke sign free agent Afellay|
|Benitez confident Ramos will stay|
|Fenerbahce issue warning to fans|
|UEFA Champions League Preview: De Boer confident Ajax are ready for Vienna test|
|Bility: I am the favourite for FIFA presidency|
|Pienaar to miss start of season|
|Vietnam 1 Manchester City 8: Sterling shines as tourists run riot|
|All-Star Keane relishing Spurs clash|
|Shaun Wright-Phillips joins brother Bradley at Red Bulls|
|Inter 0 Real Madrid 3: Rodriguez stunner caps comfortable win|
|Villa sign Ayew|
|Watford complete Berghuis transfer|
|Robben returns to Bayern training|
|Pulis anxious to make West Brom additions|
|David Luiz eager to welcome ´fantastic´ Di Maria|
|Fernando injury free ahead of new campaign|
|Hummels blames weight issues for poor season|
|Defoe hoping for early Sunderland goals|
|Depay hints at identity of ´surprise´ United striker|
|Tigres UANL v River Plate: Hosts look to bounce back and make history|
|Crespo set for Villa move|
|Terry: I would never join a Premier League rival|
|Van Gaal coy on United future|
|Romero to cover potential De Gea exit - Van Gaal|
|Uruguay win men´s football gold at Pan Am Games|
|Pirlo thanks New York City fans for ´beautiful´ welcome|
|Mexico capitalised on ´the mistakes we made´ - Schafer|
|Herrera delighted with Mexico display|
|MLS Review: Whitecaps build happy home, Pirlo debuts|
|Guardado wins Golden Ball at Gold Cup|
|NZF confirms Olympics disqualification appeal|
|Jamaica 1 Mexico 3: CONCACAF giants complete form turnaround|
|New York Red Bulls 2 Benfica 1: Another scalp for MLS side|
|Romero signs with United|
|Moghreb Tetouan 1 Al Hilal Omdurman 1: Visitors go top|
|Van Gaal rules out Ronaldo bid|
|Pique open to Barca captaincy|
|Pirlo makes MLS bow in thrilling NYC victory|
|Coutinho and Can return for Liverpool U21s|
|Walcott deal ´closer´, says Wenger|
|Arsenal 1 Wolfsburg 0: Walcott the match-winner in Emirates Cup finale|
|Di Santo links up with Schalke squad|
|Lukaku treble sinks Hearts|
|Benitez again refutes Ronaldo rift rumours|
|Pepe sure Ramos will stay at Real|
|City target De Bruyne named Germany´s Player of the Year|
|Montero spoils McCarthy´s Palace debut|
|Lyon 0 Villarreal 2: Soriano, Baptistao seal comfortable win in Emirates Cup|
|Wijnaldum on target as Newcastle are held|
|Mourinho: Rivals trying to buy the title|
|Jovetic set for Inter medical|
|RFS in ´denial´ over racism issue, claims Football Against Racism in Europe|
|Salah not staying at Chelsea - Mourinho|
|Mbemba closes in on Newcastle switch|
|Ibrahimovic: Di Maria will take PSG to another level|
|Delph: Don´t compare me to Pogba|
|Dundee United sign Sneijder|
|Morata relishing new-look Juve strikeforce|
|Strachan "not scared" of England after World Cup qualifying draw|
|Brazil claim football, basketball, handball gold in Toronto|
|Lampard´s debut delayed again, Pirlo ready to play|
|Mourinho open to Premier League matches in US|
|MLS Review: Texas unites to hurt Galaxy|
|Luis Enrique: United can emulate Barca revival|
|Van Gaal singles out Januzaj, hails United´s forwards|
|Blanc still hopeful PSG will sign Di Maria|
|Irish international Cunningham seeks Bristol City exit|
|Italy embracing Spain challenge in World Cup qualifying|
|Dos Santos brothers in doubt for Gold Cup final|
|PSG 1 Chelsea 1 (aet, 5-6 on penalties): Courtois clinches victory for Mourinho´s men|
|United States 1 Panama 1 (aet, 2-3 on penalties): Mejia denies hosts third|
|ES Setif 1 Al Merreikh 1: Sudanese deny title-holders at home|
|CONCACAF admit referee errors in Gold Cup semi-final|
|Dutch favourites in Group A - Deschamps|
|Barcelona 1 Manchester United 3: Rooney, Lingard and Januzaj maintain winning start|