Roy Hodgson refused to blame an experimental line-up for England's 2-0 friendly defeat to Chile at Wembley and paid tribute to the visitors.
Celtic goalkeeper Fraser Forster was handed his debut behind a defence that featured Manchester United's Phil Jones starting at centre-back for the first time at international level, while in-form Southampton duo Jay Rodriguez and Adam Lallana earned maiden caps as they flanked Wayne Rooney in attack.
But, despite a promising start with Lallana impressing, Alexis Sanchez headed the visitors into a seventh-minute lead by stealing a march on Leighton Baines, who was preferred to Ashley Cole at left-back by Hodgson.
Cole's fellow Chelsea defender Gary Cahill then ceded possession early in stoppage time as England pushed for an equaliser, allowing Sanchez to delightfully dink over Forster and condemn Hodgson's men to their first loss since last November.
"Not totally," Hodgson told ITV when asked whether his unfamiliar selections caused the reverse. "To be fair, we played against a very good team.
"From a goal down it was always going to be difficult. I thought we came back into the game well towards the end of the first half and at the start of the second half.
"But unfortunately, playing against these very skilful teams and these teams who know how to take the sting out of games, the longer the game went on there seemed to be more minor fouls, more stoppages - not helped of course by all of the changes.
"And I thought, to be frank, that Chile were the better team tonight. I thought they played very, very well.
"We were a bit unlucky to lose it by two goals to nil, the last one where we were pushing forward with the unfortunate mistake, but we learnt a lot of things tonight.
"We learnt a lot about our squad of players but also we learned a lot about what it's going to be like to play against South American opposition."
Frank Lampard was England’s captain for the game and received a commemorative golden cap before kick-off from his father Frank Snr and Geoff Hurst to celebrate bringing up 100 international appearances when England booked their place at Brazil 2014.
And the veteran midfielder reserved praise for Lallana after observing a bright and industrious beginning to the 25-year-old's own international career.
"I thought he was very lively. Both the Southampton boys deserved their place on merit with the way they're playing.
"Adam had a couple of chances and on another day he might have had two goals on his debut."
|Coach: R. Hodgson|
for J. Rodriguez 57'
for P. Jones 57'
for J. Milner 66'
for F. Lampard 71'
for J. Wilshere 71'
for A. Lallana 77'
|Benfica deserved to win, says Jesus|
|Rodgers will ´deal with´ shirt-swapping Balotelli|
|Jardim disappointed with Monaco attack|
|Tevez calls for mental change at Juventus|
|´Proud´ Ronaldo not focusing on Raul record|
|Wenger hails Arsenal spirit|
|Klopp salutes quick start in Dortmund rout|
|Ludogorets 1 Basel 0: Bulgarians secure historic triumph|
|Bayer Leverkusen 2 Zenit 0: Russians´ streak ends at 16|
|Anderlecht 1 Arsenal 2: Gibbs, Podolski score late for visitors|
|Olympiacos 1 Juventus 0: Roberto heroics help win it for hosts|
|Atletico Madrid 5 Malmo 0: Koke stars as Simeone´s men ease to win|
|Monaco 0 Benfica 0: 10-man visitors claim dour draw|
|Liverpool 0 Real Madrid 3: Ronaldo scores again as European champions stroll on Merseyside|
|Galatasaray 0 Borussia Dortmund 4: Klopp´s men rampant in Istanbul|
|Championship Preview: Watford and Boro battle at the top|
|Platini demands CAF apology|
|Metalist 0 Legia Warsaw 1: Dazzling Duda seals victory|
|Martinez: Lille double-header like a cup final|
|Evans seeks ´second chance´ after release from prison|
|MLS Preview: Whitecaps, Timbers chase final play-off spot|
|Bellusci is no racist - Cellino|
|Thai Premier League Review: Chonburi go top, Air Force Central and Songkhla relegated|
|UEFA rule out CSKA punishment|
|J.League Review: Urawa extend lead despite draw, Tokushima relegated|
|UEFA investigating Luiz Adriano allegations|
|Bentaleb out of Asteras Tripolis clash|
|Rafael: Chelsea are beatable|
|Cannavaro assets seized in tax fraud probe|
|Leverkusen ordered to repay over €16m to former sponsor|
|Remy hopeful of facing United|
|Gerrard: I may regret Real snubs|
|FA investigating Jerome racism allegation|
|Alcaraz takes over at Levante|
|Wenger backs Martinez to take his chance|
|Benatia: Media judged me too soon|
|CAF hits out at Platini|
|Mourinho calm over striker shortage|
|Kompany fumes at presence of CSKA fans|
|CONCACAF Champions League Review: Timbers eliminated|
|Jerome complains of racial abuse|
|Lanus 1 Cerro Porteno 1: Paraguayans reach quarters|
|A-League Preview: Another blow for Melbourne City ahead of derby|
|Luiz Adriano alleges racism|
|Yermakovich laments lack of quality, errors|
|Lopetegui pleased with important win|
|Luiz Adriano overjoyed with record-equalling haul|
|Blanc hails PSG´s fighting spirit|
|Melbourne City confirm Villa departure|
|Mixed feelings for Donis|
|Chelsea are ´serious contenders´ - Simundza|
|Valverde remaining positive|
|Silva slams penalty decision after Sporting loss|
|De Boer unhappy with early Ajax caution|
|League Two Review: Wycombe lose at Exeter, Burton win thriller|
|Championship Review: Derby go top, Birmingham struggles continue|
|Guardiola plays down dominant Bayern win|
|Schalke grateful for controversial penalty win|
|Rakitic takes heart from Barca performance|
|League One Review: Crewe run continues as Preston win again|
|Garcia accepts blame for Bayern mauling|
|UEFA Europa League Preview: Sevilla, Napoli hit the road|
|Drogba delight as Maribor pay the penalty|
|Schalke 4 Sporting Lisbon 3: Choupo-Moting heroics earn Di Matteo incredible win|
|BATE 0 Shakhtar Donetsk 7: Luiz Adriano the five-goal hero|
|APOEL 0 Paris Saint-Germain 1: Late Cavani strike seals victory|
|Barcelona 3 Ajax 1: Messi and Neymar help sink Dutch champions|
|Chelsea 6 Maribor 0: Drogba on target in comfortable success|
|Porto 2 Athletic Bilbao 1: Quaresma leaves it late to ensure maximum points|
|Roma 1 Bayern Munich 7: Guardiola´s men run riot in Rome|
|Slutsky delighted with CSKA spirit|
|Sloppy City frustrate Pellegrini|
|Lille v Everton: Martinez´s men look to continue recovery|
|Tottenham v Asteras Tripolis: Spurs begin big week with group leaders|
|Bale out of Clasico, confirms Ancelotti|
|Galatasaray the perfect test for Dortmund, says Klopp|
|CSKA Moscow 2 Manchester City 2: Visitors remain winless after spurning two-goal lead|
|Rodgers plays down Bale absence|
|Allegri urges Juventus to keep calm|
|Subotic wants confidence-boosting victory|
|Fernandes apologises for Taarabt-Redknapp spat|
|Lopes hopeful of return after mini-stroke|
|Gabi to miss out for Atletico|
|Inter v Saint-Etienne: Mazzarri´s men eye next step to last 32|
|Hasi warns of Arsenal threat|
|Verona hit with fine and partial stadium closure|
|Sunderland players offer fans refund after Southampton mauling|
|Schmidt wants Leverkusen reaction|
|Redknapp: Taarabt the worst professional I have ever come across|
|´I haven´t been up to my full potential´, admits Shaw|
|Flamini: Injuries no excuse for Arsenal form|
|Busquets to miss Ajax clash|
|Bale out of Anfield clash|
|Levante sack Mendilibar|
|Platini talks down Ronaldo´s Ballon d´Or chances|
|Messi and Ronaldo out of this world in UEFA Champions League space race|
|Bring on Bilbao - Lopetegui|
|J.League Preview: Petrovic positive despite Urawa form|
|Argentine Primera Division Review: Calleri inspires Boca|
|Guardiola: Garcia´s Roma reign ´wonderful´|
|Chilean Primera Division Review: Colo Colo claim key win|
|Mata had ´no relationship´ with Mourinho|
|Paraguayan Division Profesional Review: Libertad gain ground, Cerro Porteno held|
|Lovren demands better display|
|´Arrogant´ Van Gaal insists United can catch Chelsea|
|Sociedad loss a ´hammer blow´ - Arrasate|
|Genoa deserved a penalty - Gasperini|
|Passion kept me at Roma - De Rossi|
|Irvine ´bitterly disappointed´, questions Fellaini´s goal|
|Taarabt hits back at Redknapp claims|
|Genoa 1 Empoli 1: Tonelli hands visitors a point|