Napoli will look to inflict further misery on Marseille when the two sides meet at Stadio San Paolo on Wednesday.
Rafael Benitez's side have won two of their three UEFA Champions League Group F encounters but sit third, behind leaders Arsenal and Borussia Dortmund on goal difference.
In a match that could prove crucial in their hopes of reaching the round of 16, Napoli are heavy favourites to beat struggling Marseille.
The French side have lost all three of their Champions League fixtures and have slid to fifth in Ligue 1 after a dreadful run of form that has seen them fail to win any of their last six matches in all competitions.
However, Benitez - who won the Champions League with Liverpool in 2005 - believes Marseille's plight will make the fixture even tougher for his side.
"We have a strong team with a lot of character," Benitez said.
"I am convinced that tomorrow (Wednesday) we will show that on the pitch. It will be important for both teams to win, and we will make sure the result goes our way.
"Marseille have lost three games in a row (in the Champions League) so it will be even more difficult for us. They will want to show they can win the game, but we will show our determination. We are in the 'group of death' as we call it."
Napoli have not lost any of their five previous home games in the Champions League, winning four, and defeated Marseille 2-1 in France last month thanks to goals from Jose Callejon and Daniel Zapata.
Callejon has now scored eight goals in 12 appearances in Europe's premier club competition, with seven of them coming for former club Real Madrid.
Napoli have not lost a Serie A match at home in 2013, winning 14 of 16 encounters, and they defeated Bologna 2-0 on Saturday.
Miguel Angel Britos (collarbone) and Camilo Zuniga (knee) are on the sidelines for Benitez's men, though.
Marseille ended a five-match losing streak at Rennes on Saturday but needed goalkeeper Steve Mandanda to save a late penalty to earn a 1-1 draw.
Jordan Ayew scored his first league goal since January in that clash, but the pressure on manager Elie Baup has not eased, with Marseille having won just twice since the start of September.
They have kept just two clean sheets in the last two months and will need a miracle if they are to become just the second team ever to qualify from the group stages after losing their first three matches.
The feat was achieved by Newcastle United in the 2002-03 season but, in a group that also contains Arsenal and Borussia Dortmund, a repeat is unlikely.
Marseille will be without Lucas Mendes (ankle), while defender Rod Fanni (adductor) is unlikely to feature.
|9||G. Higuaín||24' 75'|
|Coach: Rafael Benítez|
for G. Pandev 66'
for D. Mertens 83'
for B. Džemaili 90'
|Juventus unveil dramatic change to club logo - but not everyone´s a fan|
|´I do not think I will return to coaching´ - Van Gaal set to call it quits|
|Torino 2 AC Milan 2: Bacca caps thrilling comeback as hosts pay the penalty|
|DR Congo 1 Morocco 0: Kabananga pounces on blunder to give 10 men the points|
|´Happy and comfortable´ Sanchez dismisses Arsenal exit talk|
|How much?! West Ham flop Simone Zaza could cost Valencia €20m|
|Mali v Egypt: Salah leads Pharaohs´ bid for AFCON glory|
|Sevilla concede they ´cannot force´ sporting director Monchi to stay|
|Ivory Coast 0 Togo 0: Reigning champions held to opening draw by Adebayor and co.|
|Goalkeeping woes, Stones and tactical confusion - How Guardiola is making life difficult for himself|
|Ozil and Sanchez can be persuaded to stay - Cech|
|Pogba: I rejected Barcelona and Real Madrid|
|Ghana v Uganda: Gyan dreams of first trophy since 1982|
|Chiellini: Juventus a work in progress|
|Robben agrees Bayern renewal until 2018|
|Hazard: Goals do not matter to me|
|Bennell pleads not guilty to eight child sex offences|
|Muller fed up with debate over Bayern role|
|Wenger glad Sanchez is not ´a Costa problem´|
|Flick resigns as DFB´s sporting director|
|Gomis ´can´t wait´ to welcome Payet to Marseille|
|Chinese FA changes foreign player rules after ´irrational´ spending|
|Like father, like son: Justin Kluivert follows in dad´s footsteps|
|´No reason to lose him´ - Marotta rubbishes talk of Allegri exit|
|Courtois: We don´t need Costa|
|Kane: Tottenham players won´t go to China|
|Noble ´angry and disappointed´ with Payet|
|Klopp furious over Matip uncertainty|
|Wenger surprised by tight Premier League|
|´Money is not everything´ - Conte issues warning amid China speculation|
|Fiorentina defeat a ´bad setback´ - Allegri|
|´This will elevate this group of players´ - Sampaoli revels in Sevilla late show|
|WATCH: Rio Ferdinand screams and dances in crazy Man Utd celebration|
|Real Madrid relaxed, admits Zidane after Sevilla defeat|
|Monaco go top of Ligue 1 with stunning Marseille victory|
|Ronaldo equals LaLiga penalty record as Real Madrid lose|
|Sevilla 2 Real Madrid 1: Stunning late comeback ends unbeaten run at 40|
|Fiorentina 2 Juventus 1: Brilliant Viola breathe life into Serie A title race|
|Tunisia 0 Senegal 2: Mane on target as favourites start strongly|
|Mourinho explains Klopp confrontation|
|Klopp delights in Alexander-Arnold display|
|Algeria must cut out mistakes against Tunisia - Leekens|
|Long balls led to Man Utd equaliser, says Klopp|
|´We attacked, Liverpool defended´ – Mourinho insists a point flattered Klopp´s men|
|DR Congo v Morocco: ´Confidence´ the Atlas Lions´ biggest hindrance ahead of AFCON opener|
|Ibrahimovic: Direct tactics worked for United|
|Guardiola rues gap to Chelsea after Goodison mauling|
|Algeria 2 Zimbabwe 2: Mahrez double prevents shock defeat|
|Manchester United 1 Liverpool 1: In-form Ibrahimovic saves hosts|
|Ivory Coast v Togo: AFCON champions hope to tame Le Roy´s ´troublemakers´|
|Guardiola lays City´s mental frailties bare after Goodison rout|
|Koeman hails ´perfect´ Everton after City mauling|
|Nice stalemate gives Monaco chance to go top|
|Guardiola suffers heaviest league loss in Everton thrashing|
|Neymar-esque Zaha is England´s loss – Bolasie|
|Everton 4 Manchester City 0: Koeman leaves old pal Guardiola´s title bid in tatters|
|Matip withdrawn from Liverpool selection over eligibility questions|
|Podolski staying at Galatasaray, insists sporting director|
|Cavani wants PSG stay|
|Torino move feels normal now – Hart|
|Chinese FA changes rule on CSL foreign players - reports|
|Bayern complete swoop for Hoffenheim duo Sule and Rudy|
|Aubameyang: Dortmund not really like Barca, Madrid or Bayern|
|Pogba can chance a game in one second - Herrera|
|Newcastle Jets 2 Perth Glory 2: Keogh´s eighth of season seals draw|
|Klopp: Liverpool ready for Old Trafford test|
|Herrera taunts Liverpool ahead of Old Trafford showdown|
|I had to be 100 per cent to stay at Boca - Tevez|
|No player is bigger than the club - Carroll takes swipe at want-away Payet|
|Icardi: I can always move to China at end of career|
|Mkhitaryan: Klopp convinced me not to join Liverpool|
|Mourinho: Pogba can score every game|
|Cameroon´s profligacy frustrates Broos|