Chelsea boss Jose Mourinho will seek an immediate response from his side when Schalke visit Stamford Bridge on Wednesday.
The UEFA Champions League Group E clash gives Chelsea – the 2011-12 champions – a chance to bounce back from a disappointing 2-0 defeat at Newcastle United on Saturday.
Mourinho was furious with the effort from his players after the Premier League match, branding their performance 'too soft' as late goals from Yoan Gouffran and Loic Remy saw Newcastle triumph.
The Portuguese has promised to make changes for the visit of Schalke as Chelsea go in search of their 100th win in UEFA competition.
"I will make changes. Not 11 changes because that would be too much, but changes for sure," Mourinho told Chelsea's official website.
"I don't know my best team because we have this kind of performance (against Newcastle)."
Chelsea top Group E with six points from three matches, having bounced back well from a shock 2-1 home defeat to FC Basel in September.
That result represented Chelsea's first loss in 30 home group-stage fixtures, but the club have since recorded two comfortable victories on the road, including a 3-0 win at Schalke last month.
Fernando Torres scored twice in Gelsenkirchen before Eden Hazard added polish to the scoreline with a late goal.
Marco van Ginkel (knee) is the only injury absentee for Chelsea, who sit second in the Premier League - five points behind table-toppers Arsenal.
Schalke enter the match on the back of a 2-0 win at Hertha Berlin on Saturday, a result that lifted them to sixth in the Bundesliga table.
Adam Szalai and young star Julian Draxler scored the goals for Schalke, who are now unbeaten in their last seven away matches, with six of those finishing in wins.
Schalke enjoyed success on their previous visit to the English capital, defeating Arsenal 2-0 in October last year.
They sit second in Group E, behind Chelsea on goal difference alone, and will be eager to atone for events in the reverse fixture, which saw the club suffer their worst home loss in the Champions League.
Schalke fans are excited about the development of Max Meyer, who became the youngest player in Bundesliga history to score in three successive games last month aged 18 years and 38 days.
Klaas-Jan Huntelaar will be missing, however, after suffering a recurrence of his knee injury in training last month.
The Netherlands forward scored four goals in last season's Champions League, but will not play again this year.
Jefferson Farfan (groin), Marco Hoger (knee) and Chinedu Obasi (tibia) will also miss the trip to Chelsea, while Greek defender Kyriakos Papadopoulos (knee) is a doubt.
Papadopoulos played 90 minutes for Schalke's reserves on Saturday but the 21-year-old has not played a first-team game this season.
|12||J. Obi Mikel|
|29||S. Eto'o||31' 54'|
|Coach: José Mourinho|
for S. Eto'o 77'
for A. Schürrle 78'
for Oscar 81'
|Stanislas brace leads Bournemouth past Yeovil|
|Watford slip to friendly defeat at Cardiff|
|Lukaku injury sours Everton win at Dundee|
|UEFA Champions League Review: Fenerbahce draw blank as Monaco impress|
|West Brom earn friendly win over Walsall|
|Vardy at the double as Leicester beat Burton|
|Atletico impress in win over Oviedo|
|Herrera sacked by Mexico after ´punch´|
|Gerrard, Keane and Bradley pull out of MLS All-Star squad|
|Marseille reach Diaby agreement|
|Sammer thrilled with Vidal´s winning mentality|
|Platini expected to launch FIFA presidency bid|
|Romanov sacked me over Barca snub - Korobochka|
|Villa complete Crespo capture|
|Wolfsberger v Borussia Dortmund: Bender praises ´fun but exhausting´ training|
|Okaka swaps Sampdoria for Anderlecht|
|Southampton v Vitesse: Fonte excited for ´dream´ sojourn into Europe|
|Bournemouth agree King compensation|
|West Ham v Astra: Kouyate confident West Ham can progress|
|Vidal completes Bayern switch, signs four-year deal|
|Fabregas calls for Champions League improvement|
|BREAKING NEWS: Filipe Luis completes Atletico return|
|Bayern to present Vidal|
|Wenger unfazed by Mourinho´s spending jibe|
|Pellegrini: Sterling will justify price tag|
|Cavani hit with two-match Uruguay ban|
|Bonucci to remain at Juve until 2020|
|No bids for Berahino - West Brom|
|Putin: Blatter deserves a Nobel prize|
|Howe: Swansea a benchmark for Bournemouth|
|New Parma to play in Serie D|
|Mata vows to hit the goal trail at United|
|Drogba ´perfect fit´ for Montreal|
|Berahino ´not yet´ ready for Tottenham - Irvine|
|Romero lauds caring Van Gaal|
|Jese flying at Real under Rafa|
|Sampdoria unwilling to pay €10m for Balotelli|
|Mourinho talks up Arsenal title chances|
|Hull sign Ryan Taylor, Sam Clucas|
|Kane, Pochettino hail MLS All-Star test|
|Di Santo sorry for swift Werder departure|
|Mourinho tells Ronaldo: Team honours come first|
|Khedira returns to Juve training|
|Celtic v Qarabag: Champions League return of utmost importance, says Collins|
|Pellegrini: Jovetic had to go|
|Manquillo completes Marseille move|
|Schalke reject Juve´s Draxler bid|
|Blanc: Di Maria deal ´close´|
|Di Santo debut ends in stalemate|
|Fire sign Drogba, trade him to Montreal Impact|
|FIFA and UEFA welcome ruling on third-party ownership|
|Juve kick off title defence against Udinese|
|Stoke sign free agent Afellay|
|Benitez confident Ramos will stay|
|Fenerbahce issue warning to fans|
|UEFA Champions League Preview: De Boer confident Ajax are ready for Vienna test|
|Bility: I am the favourite for FIFA presidency|
|Pienaar to miss start of season|
|Vietnam 1 Manchester City 8: Sterling shines as tourists run riot|
|All-Star Keane relishing Spurs clash|
|Shaun Wright-Phillips joins brother Bradley at Red Bulls|
|Inter 0 Real Madrid 3: Rodriguez stunner caps comfortable win|
|Villa sign Ayew|
|Watford complete Berghuis transfer|
|Robben returns to Bayern training|
|Pulis anxious to make West Brom additions|
|David Luiz eager to welcome ´fantastic´ Di Maria|
|Fernando injury free ahead of new campaign|
|Hummels blames weight issues for poor season|
|Defoe hoping for early Sunderland goals|
|Depay hints at identity of ´surprise´ United striker|
|Tigres UANL v River Plate: Hosts look to bounce back and make history|
|Crespo set for Villa move|
|Terry: I would never join a Premier League rival|
|Van Gaal coy on United future|
|Romero to cover potential De Gea exit - Van Gaal|
|Uruguay win men´s football gold at Pan Am Games|
|Pirlo thanks New York City fans for ´beautiful´ welcome|
|Mexico capitalised on ´the mistakes we made´ - Schafer|
|Herrera delighted with Mexico display|
|MLS Review: Whitecaps build happy home, Pirlo debuts|
|Guardado wins Golden Ball at Gold Cup|
|NZF confirms Olympics disqualification appeal|
|Jamaica 1 Mexico 3: CONCACAF giants complete form turnaround|
|New York Red Bulls 2 Benfica 1: Another scalp for MLS side|
|Romero signs with United|
|Moghreb Tetouan 1 Al Hilal Omdurman 1: Visitors go top|
|Van Gaal rules out Ronaldo bid|