Atletico Madrid can seal a place in the round of 16 with victory over Austria Vienna in the UEFA Champions League on Wednesday.
The La Liga high-flyers top Group G after winning their opening three matches and will enter the home fixture against their struggling opponents as red-hot favourites.
Atletico have won 11 of their 12 league fixtures this season, helping them to second place in the table, just one point behind Barcelona.
They sit five points ahead of city rivals Real Madrid, largely thanks to the form of forwards Diego Costa and David Villa.
Costa has been outstanding for Diego Simeone's side, scoring 15 goals in as many appearances in all competitions.
His latest effort - which came in Sunday's 2-0 home success against Athletic Bilbao, when Villa also scored to take his tally to seven - led Simeone to lavish him with praise.
"Diego is huge in every way," Simeone said. "On top of the goal he scored, he is growing as a player – he is more of a team player and helps us win the ball back.
"All of that makes the whole team play better. We hope he continues to grow because he's got many years ahead of him to get even better."
Costa missed the first two matches of this year's group stage due to a suspension incurred in last season's Europa League, but he scored twice in Atletico's 3-0 win at Austria Vienna last month.
Atletico have never won four consecutive matches in the Champions League and are aiming to qualify for the knockout rounds of the competition for the first time since the 2008-09 campaign.
Austria Vienna sit on the bottom of Group G with just one point from their three matches and the visitors' league form suggests an upset is highly unlikely.
Although they beat Wiener Neustadt 3-0 on Sunday in the Austrian Bundesliga, they are fifth after a dreadful run.
Head coach Nenad Bjelica – who will serve a touchline ban for the fixture – saw his side win just one of 12 matches before Sunday's triumph.
Their goalless draw against Zenit last month was the first Champions League point won by an Austrian side since 2001 and their inexperience is highlighted by the fact that just two of their players – strikers Tomas Jun and Roman Kienast – have played in Europe's premier club competition before this season.
Bjelica will be without Alexander Grunwald and Alexander Gorgon (both knee) and Marko Stankovic (muscular problem).
|19||Diego Costa||75' 82'|
|Coach: D. Simeone|
for Adrián 46'
for Tiago 56'
for Koke 66'
|Andre Gomes can play in Busquets role, insists Luis Enrique|
|Aguero´s dangerous tackle scared me, says Conte|
|Guardiola: We are killing the players|
|Bournemouth announce plans for new stadium|
|Former Bayern Munich and Real Madrid star Ze Roberto to play beyond 43rd birthday|
|Barcelona friendly awaits new Chapecoense coach Mancini|
|Arsenal are privileged to have Sanchez and Ozil - Monreal|
|Watzke denies agreement to discuss Aubameyang transfer with Madrid|
|Paris Saint-Germain v Nice: Champions hunting down shock leaders|
|Giggs tells Rashford how to end his goal drought|
|Manchester United without Shaw, Smalling for Tottenham clash|
|Willems inks PSV renewal|
|Costa and Conte scoop Premier League awards|
|Conte detained on suspicion of assault|
|Strootman ban for derby ´simulation´ overturned|
|Mourinho demands more goals from Rooney|
|Bobo preserves Sydney´s unbeaten start in Cup final rematch|
|Luis Enrique: I don´t dare predict if Messi will renew|
|Mourinho admits changing style for United|
|Sanchez talk is disrespectful, says Conte|
|Sassuolo 0 Genk 2: Visitors seal top spot|
|Sterling back for City as Guardiola predicts tough Leicester test|
|Mourinho still the ´Special One´ for Pochettino|
|Matic return leaves Conte with Fabregas dilemma|
|Guardiola expects greater impact from City youngsters next season|
|Klopp defends Karius after Bournemouth blunder|
|Pirlo visits Chelsea - but Conte is not signing him|
|Ronaldo, Modric rested for Deportivo clash|
|Tuchel hails returning Reus|
|Klopp has ´no idea´ on Sturridge return|
|´My players are intelligent and good people´ - Zidane on Ronaldo´s taxes|
|Atletico to play at ´Wanda Metropolitano´|
|Real Madrid to rest Benzema and start Morata against Deportivo|
|Ancelotti rules out Draxler bid as Bayern prepare for barren transfer window|
|Ighalo calls on Watford to sign Mikel|
|Pardew wants defender and striker to bolster Palace survival push|
|Moyes: M´Vila doesn´t have the fight for Sunderland|
|Leipzig only built to earn Red Bull money - Watzke|
|Shenhua director blasts CSL imports... but desperate for Tevez deal|
|Ribery: Bayern my last club in Europe|
|Hughes targets Arsenal fans to help Stoke end dismal away run|
|83 suspects, 98 clubs ´impacted´ in football abuse probe|
|Fowler pleads with Liverpool to keep ´top quality´ Sturridge|
|Reus ´100 per cent different´ on comeback|
|Ibrahimovic ´super happy´ for rejuvenated Mkhitaryan|
|Vertonghen: Football needs Mourinho|
|Title triumph went to Leicester´s heads, admits Ranieri|
|Conceicao named new Nantes coach|
|LaLiga lead means nothing - Zidane|
|Chapecoense add two stars to badge in wake of air disaster|
|Blatter accuses Infantino of lack of respect|
|Austin injury compounds Puel´s misery|
|Gestifute publishes further evidence of ´Ronaldo tax compliance´|
|Pioli eyes further Inter improvement|
|´I feel s***´ - Van Dijk blasts Southampton after Europa League collapse|
|Mourinho marvels at Mkhitaryan mentality after Zorya stunner|
|Southampton 1 Hapoel Be´er Sheva 1: Late Van Dijk leveller not enough as visitors progress|
|Inter 2 Sparta Prague 1: Eder double sends hosts out on a high|
|Vieira wanted Arsenal coaching opportunity|
|Vieira hopes MLS experience puts him in frame to replace Guardiola|
|Mkhitaryan: I waited a long time for this|
|Zorya 0 Manchester United 2: Mkhitaryan magic sends Mourinho´s men through|
|Ranieri urges Leicester players to fight for their futures|
|Cellino banned for 18 months over McCormack transfer|
|Koeman demands reaction from dropped Barkley|
|Tevez unsure on Boca future amid China speculation|
|Bradley vows to fight for his job at Swansea|
|Koeman speaks out on Depay, Schneiderlin links|
|Wenger unconvinced by World Cup expansion plans|
|Kovac brothers sign new Frankfurt deals|
|Selling Sturridge would be a mistake, says Rush|
|UEFA opens disciplinary proceedings against Besiktas, Dynamo Kiev|
|Filipe Luis suffers thigh tear|
|Kashima Antlers 2 Auckland City 1: Late Kanazaki header the difference|
|Suarez´s Barca renewal already done, says Bartomeu|
|Barcelona invite Chapecoense for Joan Gamper Trophy|
|Arsenal would have a chance against Real Madrid, insists Wenger|
|FIFA chief Infantino calls for zero tolerance on child abuse|
|Sanchez will not leave Arsenal for China - Wenger|
|Dybala delighted with Juventus return|
|Rashford desperate to learn from Ibrahimovic|
|Weigl not ready for Real Madrid - Tuchel|
|Why Zidane must drop Ronaldo at the Club World Cup|
|Barton: They built me up into a Neymar-Messi type|
|Shakhtar aware of Barca interest in Srna - Fonseca|
|Mets hitting coach believes Tebow can make it to MLB|
|Aubameyang reiterates Madrid dream after Bernabeu show|
|Zidane praises Benzema after 50th Champions League goal|
|Aubameyang deserves 99 per cent of credit - Reus|
|Neymar: There´s only one Ballon d´Or winner and it´s Messi, not Ronaldo|
|Magiera hails Legia victory as for ´all of Poland´|
|Tuchel thought Aubameyang had blown chance to equalise|
|Pochettino confident Spurs are back on track|
|Santo hails Porto´s mature performance|
|Lyon proved we can compete with Europe´s best - Genesio|
|Slutsky unsurprised by apparent Premier League interest in Dzagoev|
|Jardim frustrated as Monaco finally lose|