Yoan Gouffran and Loic Remy gave Newcastle United a 2-0 win over Chelsea as Jose Mourinho's poor St. James' Park record continued.
The Chelsea manager entered the match with just two points from his previous three visits to Newcastle, and watched on as his side wasted a chance to move to the top of the Premier League table on Saturday.
Chelsea controlled a first half devoid of clear-cut chances – their best effort saw John Terry hit the crossbar with a header – but were left reeling when Gouffran headed in an inviting Yohan Cabaye free-kick in the 68th minute.
Substitutes Willian and Samuel Eto'o went close for Chelsea in the latter stages, but Remy hammered home Vurnon Anita's cut-back with two minutes left to seal Newcastle's win.
The loss was Chelsea's second of the league campaign, meaning Arsenal could go five points clear if they beat Liverpool on Saturday.
Mourinho made two changes from the side that beat Manchester City in their last Premier League fixture, with Juan Mata and David Luiz replacing Andre Schurrle and Gary Cahill respectively.
Newcastle also made two alterations, with defender Mapou Yanga-Mbiwa returning from suspension and Shola Ameobi selected, as Hatem Ben Arfa and Paul Dummett (hamstring) made way.
In a scrappy first half, Chelsea came close to an opener when Terry's thumping header hit the bar in the 13th minute.
Chelsea begun strongly but failed to create a clear openings until the captain's chance, which came when he rose above Mike Williamson to nod Mata's corner against the woodwork, while Branislav Ivanovic's follow-up deflected onto the top of the bar.
Another Terry header almost led to a goal, with his effort cleared off the line by Davide Santon, and at the other end, Moussa Sissoko – scorer of two goals in Newcastle's 3-2 win over Chelsea in February – forced a smart save from Chelsea goalkeeper Petr Cech at the near post seven minutes before the break.
Newcastle skipper Chieck Tiote limped off with an apparent thigh injury eight minutes after the break but that did not stop them from enjoying a terrific spell around the hour-mark.
Sissoko was first to go close, forcing Cech to tip wide when released by Mathieu Debuchy, before Remy shot straight at the goalkeeper from close range.
Gouffran had a good effort saved by Cech at the near post in the 66th minute and three minutes later, Newcastle's pressure told, with the Frenchman breaking the deadlock by nodding in Cabaye's excellent free-kick.
They quickly went in search of a second, with Terry making an excellent sliding tackle to deny Remy after he linked well with Sissoko, before Eto'o had an effort deflected wide by Yanga-Mbiwa.
A clever Oscar cut-back let Willian in with 10 minutes remaining, but his shot was well saved by Newcastle goalkeeper Tim Krul, and a follow-up from Eto'o hit Debuchy and went wide.
And Newcastle wrapped up their victory in the 88th minute, as Remy produced a powerful finish to convert Anita's clever assist.
|14||L. Rémy||89' 90'|
|Coach: A. Pardew|
for C. Tioté 53'
for Shola Ameobi 62'
for Y. Gouffran 84'
|O´Neill delighted with second-half display|
|First-half dominance pleases Deschamps|
|Muller criticises Germany profligacy|
|Euro 2016 Qualifying Review: Portugal go top, Gibraltar make history in defeat|
|Liverpool the only English club I could play for - Suarez|
|France 2 Denmark 0: Lacazette off the mark in routine victory|
|Republic of Ireland 1 Poland 1: Long rescues vital point|
|Portugal 2 Serbia 1: Coentrao puts hosts top of Group I|
|Strachan hails ´terrific´ Gibraltar|
|Lafferty back playing with a smile on his face - O´Neill|
|Toure to reveal Ivory Coast future over coming days|
|Georgia 0 Germany 2: Reus and Muller on target for world champions|
|Northern Ireland 2 Finland 1: Lafferty inspires fourth qualifying success|
|Scotland 6 Gibraltar 1: Casciaro´s historic moment outshone by Fletcher´s hat-trick|
|France 2-0 Denmark: Lacazette and Giroud on target|
|Firmino hopeful of Copa America spot|
|Hummels considering options at Dortmund|
|Suarez goalless on Anfield return, but Balotelli nets stunner|
|Casciaro scores first competitive goal for Gibraltar|
|Fleetwood Town 1 Preston North End 1: Ball stunner claims share of derby spoils|
|Italy v England: Judge me on results, says Conte|
|Colombia v Kuwait: Falcao seeking another strong showing|
|Brazil 1 Chile 0: Firmino settles scrappy affair|
|Luxembourg v Turkey: Let´s kick on, urges Terim|
|South Africa 1 Nigeria 1: Zungu strikes late to earn draw|
|Smalling wants long-term United stay|
|South Africa 1-1 Nigeria: Last-gasp Zungu goal cancels out Musa strike|
|Italy call up Santon and Abate for England friendly|
|Switzerland v United States: Klinsmann eyes learning curve|
|Netherlands v Spain: Hiddink has players´ support, says Wijnaldum|
|A-League Review: Sydney end Wellington run, Adelaide suffer injury blows in Jets win|
|Henderson eyes long-term Liverpool future|
|I have nothing to prove - Bale|
|Brazil 1-0 Chile: Firmino gives Selecao battling victory|
|South Korea v New Zealand: All Whites looking to future|
|Japan v Uzbekistan: Hosts eye another win under Halilhodzic|
|MLS Review: Kaka nets in Orlando draw|
|Mexico 1 Ecuador 0: Hernandez, Corona help Herrera´s men to victory|
|Deschamps calls for France response|
|Dunga unfazed by pressure|
|Montenegro fan turns himself in after flare incident|
|Injured Messi not ready - Martino|
|Hodgson: Rooney not close to Charlton|
|Terim proud of Turkey|
|Hiddink happy with point|
|Euro 2016 Qualifying Review: Netherlands and Italy stage late escapes|
|Debutant Eder delighted with Azzurri bow|
|Argentina 2 El Salvador 0: Mancuello nets debut goal in straightforward win|
|Kovac not satisfied despite Croatia victory|
|Netherlands 1 Turkey 1: Huntelaar spares Hiddink from historic home loss|
|Ghana 1 Senegal 2: Konate brace downs Black Stars|
|Bulgaria 2 Italy 2: Controversial debutant Eder rescues Conte´s men|
|Morocco 0 Uruguay 1: Cavani spot-kick seals win|
|Al Sadd say talks with Xavi ongoing|
|McClean slams Sunderland´s handling of poppy controversy|
|Ghana 1-2 Senegal: Black Stars continue Afcon hangover|
|Cheltenham player diagnosed with cancer|
|Palace takeover talk premature - Parish|
|Odegaard becomes Euro qualifiers´ youngest starter|
|Job not done yet, Bale warns Wales|
|Israel 0 Wales 3: Brilliant Bale bags brace as Wales go top|
|Dunga backs Neymar to overhaul Pele´s Brazil goal record|
|League Two Review: Hartlepool climb out of drop zone, Cheltenham go bottom|
|El Salvador 0-2 Argentina: Martino's men triumph without Messi|
|League One Review: Canavan leaves it late to deny County|
|Freddy Adu signs with 11th team in as many years|
|Besiktas deny Cech, Danny rumours|
|Puerto Rico v Canada: Haber targets more momentum|
|Miranda not contemplating Atletico exit|
|Austin relaxed over England prospects|
|Manchester United should sign Ibrahimovic - Schmeichel|
|Ibe eyes Liverpool run-in|
|Bertrand called up by England as withdrawal of four players confirmed|
|A-League Review: Risdon nets stunner, Germano tames Roar|
|Panama v Costa Rica: Unbeaten run a secondary concern for Wanchope|
|Italy coach Conte shaken after death threats - FIGC chief|
|Barca fears over Alba eased|
|Schweinsteiger to start Germany qualifier|
|Akinfeev thanks fans after flare incident|
|Injuries offer Kane chance of first England start|
|Russian Football Union to protest following Montenegro abandonment|
|October comeback the target for injured Foster|
|Van der Vaart looks set to leave Hamburg|
|Bale focused on Wales - Coleman|
|Kluivert helps Curacao to victory|
|Hamstrung Alba returns to Barcelona|
|Macedonia v Australia: Confident visitors eye victory|
|Akinfeev to return to Moscow with Russia squad|
|Brnovic: Montenegro have no chance of qualifying|
|Russia had to resume after Akinfeev incident - Capello|
|Terim: Robben absence important|
|Brazil - Chile Preview: Winning is 'our only option' - Dunga|
|France - Denmark Preview: Olsen hits out at 'disrespectful' hosts|
|Morata keen to keep working|
|Canada 1 Guatemala 0: Haber heads Floro´s men to win|
|Difficult to find a place for Kane in starting XI - Hodgson|
|Difficult to find a place for Kane in starting XI - Hodgson|