Sevilla coach Unai Emery believes the sale of Alvaro Negredo to Manchester City would be the best result for both clubs.
The English Premier League giants are closing in on the Spain attacker, having signed his team-mate Jesus Navas for an initial fee of £14.9million in June.
Funds are much-needed at Sevilla and Emery has given the strongest indication yet the 27-year-old could leave the La Liga club, who are reportedly trying to push his price beyond £20m.
"The most likely situation is that he will leave," Emery said.
"The cards are on the table. Negredo is a very important player to Sevilla and he could continue to be one, either by staying here or by earning the club a big transfer fee.
"We know he could leave, but it would be the best for everyone.
"The club would be able to meet its financial obligations, and although we would lose a key player, we need to be reasonable, like we were in the case of Navas.
"Our aim is to produce new players that can reach the same heights.
"It's possible the club can't reach an agreement for him, but we are prepared, we have spent some time working on alternatives.
"Of course we're not going to find a player with the same characteristics as him or one who is going to have the same record.
"But we will find players who will be important to the future of this club, and I trust the work the club is doing in that area."
City are also chasing highly rated Fiorentina forward Stevan Jovetic, 23, and could sign the Montenegro international and Negredo.
City manager Manuel Pellegrini has been eyeing a striker in the off-season to fill the void left by Carlos Tevez, who has joined Juventus.
But renewed speculation about a move for Paris Saint-Germain star Zlatan Ibrahimovic has been dismissed.
|Frontzeck: Survival fight is not about me|
|Real can cope with injuries - Ancelotti|
|Dnipro v Club Brugge: Preud´homme prepares to show his hand|
|Silva returns to training after cheekbone scare|
|Villa and Reading charged over alleged FA Cup crowd trouble|
|Zeman resigns from Cagliari post|
|Opportunity knocks as Dyche plans for Barnes absence|
|Berbatov dreaming of Champions League semi-final|
|Benzema joins Real´s injury list|
|Jenkinson: West Ham will not settle for mid-table|
|Montella calm over fan frustrations|
|Blanc: Barca are the model for PSG|
|Newcastle just need three more points - Janmaat|
|Gaya: Six finals left for Valencia|
|Muller wary of Porto counter-attacks|
|Bartomeu plays down Pogba link|
|Verratti hails ´essential´ Ibrahimovic|
|Zidane backs PSG to upset Barca|
|America v Montreal Impact: Klopas unfazed by host´s form|
|Vlaar open to Villa stay|
|Shepherd urges fans not to boycott Newcastle|
|Maritimo 1 Nacional 1: Tiquinho ensures derby finishes all square|
|Fiorentina 0 Verona 1: Diamanti and Neto pay the penalty|
|Elche 1 Real Sociedad 0: Bergara gifts win to hosts|
|Van Persie returns in Under-21 game|
|Turkish Super Lig Review: Galatasaray slip sees Fenerbahce go top|
|Russian Premier League Review: Arsenal Tula and Rostov maintain survival bids|
|Frontzeck named as Korkut´s replacement at Hannover|
|Lopetegui wary of Bayern backlash|
|Pastore plays down Cantona´s world best tag|
|PSG absences no excuse for failure - Blanc|
|Suarez sad to see Gerrard leaving Liverpool|
|Cleber injury adds to Hamburg woes|
|Northern Ireland free to play Romania at Windsor Park|
|Juve sweating on Vidal availability|
|Monaco v Juventus: Evra ready to take control|
|Striking concerns for Chelsea after Drogba injury|
|PSG and Chelsea have bid for Dybala, claims agent|
|Pogba can leave Juve for ´right offer´|
|Bendtner dropped after arriving late for training|
|Messi achievement unrepeatable, says Luis Enrique|
|Football League Preview: Preston and MK Dons battling to join Bristol City|
|Real Madrid v Atletico Madrid: Ancelotti optimistic amid injury concerns|
|Iniesta declared fit for PSG second leg|
|Bale remains a doubt for Atletico clash|
|Schweinsteiger set to face Porto, Ribery to miss out|
|No broken cheekbone for Silva|
|Final appearance can remove negativity at Villa - Fox|
|Bale selected in Football League Team of the Decade|
|PSV director: United and PSG want Depay|
|Korkut sacked by relegation-threatened Hannover|
|Sherwood: Pressure all on Arsenal|
|Newcastle in a ´dangerous moment´ - Colback|
|Kovac hopes to have Modric fit for Euro qualifier|
|Copa Libertadores Preview: Cruzeiro boss Oliveira does not fear sack|
|MLS Review: Revs extend unbeaten run, Timbers stun City|
|Fournier proud and disappointed|
|Shaw ready to make an impact|
|Hazard among best three in the world - Mourinho|
|Carver: Newcastle are in relegation battle|
|CAF Champions League Review: Setif get two away goals, Al Ahly denied late on|
|Inzaghi praises Milan derby officials|
|La Liga Review: Granada frustrate Sevilla, Villarreal´s woes continue|
|Inter should have had a penalty, Mancini fumes|
|Ligue 1 Review: Lyon return top after derby draw|
|Inter 0 Milan 0: Disappointing derby ends in stalemate|
|Primeira Liga Review: Sporting made to battle, Penafiel running out of time|
|Balotelli targets officials in latest social media outburst|
|Bundesliga Review: Werder Bremen edge Nordderby, De Bruyne rescues Wolfsburg|
|Serie A Review: Napoli close on stumbling Roma|
|Pochettino congratulates 30-goal Kane|
|Rodgers questions Liverpool´s mental strength|
|Carver counting on experience after latest defeat|
|Sherwood marvels at Grealish potential|
|Eredivisie Review: Dordrecht relegated as Go Ahead Eagles stun Feyenoord|
|Newcastle United 1 Tottenham 3: Losing streak continues amid fan boycott|
|Kouyate elbow on Silva accidental - Allardyce|
|Aston Villa 2 Liverpool 1: Delph ends Gerrard´s hopes of dream farewell|
|Pellegrini hails City response to derby defeat|
|Silva back home after Kouyate elbow|
|Manchester City 2 West Ham 0: Silva injury sours routine win|
|Bayern Munich v Porto: Neuer rallies Germans for uphill battle|
|Barcelona v Paris Saint-Germain: Marquinhos keeps the faith ahead of Camp Nou test|
|Fer closes in on QPR return|
|Crouch set for surgery|
|Dortmund confirm Tuchel as Klopp replacement|
|Adams leaves relegation-threatened Tranmere|
|Real still unsure over Modric injury|
|Tevez rubbishes Juve exit talk|
|Moyes: I had to fight to keep Rooney at United|
|Perth Glory 3 Melbourne City 1: Maclaren treble the difference|
|Dyche: Burnley are too honest|
|Illarramendi eager for Real stay|
|Hazard issues Chelsea warning|
|MLS Review: Injury-time winner buoys Galaxy, Martins shows class for Sounders|
|Pastore talents ´unpredictable´ - Blanc|
|Liverpool much bigger than City - Rodgers|
|AFC Champions League Preview: Evergrande look to progress|
|Clarke expects distraught Federici to bounce back|
|Toure is City´s scapegoat - agent|
|Allegri praises high-flying Juve|
|Athletic Bilbao 4 Getafe 0: Hosts end winless run|