La Celeste’s attacking trio of Luis Suarez, Diego Forlan and Edinson Cavani may start together for the first time since the 3-0 qualifying defeat to Argentina last October.
Spain are on a 17-match unbeaten run (W13, D4) stretching back to November 2011.
La Roja have won two of their last three encounters against Uruguay.
Carles Puyol (pictured, right) will become the seventh player to reach 100 appearances for Spain if he plays on Wednesday.
Uruguay have won just one of their last six matches (W1, D2, L3).
The South Americans are fifth in the Conmebol qualifying zone, eight points off leaders Argentina.
Luis Suarez needs four more strikes to overtake Diego Forlan’s record of 33 goals and become Uruguay’s all-time leading scorer.
1 - 0 |
||
1 - 1 |
||
2 - 1 |
||
3 - 1 |
| Player | Bookings |
|---|---|
| Valdés | |
Puyol
|
|
| Sergio Ramos |
 56'
|
| Azpilicueta | |
|
Jordi Alba
|
56'
|
| Fàbregas |
 16'
|
|
Iniesta
|
|
|
Cazorla
|
|
| Busquets |
22'
|
|
Mata
|
|
|
Pedro
|
51'
74'
|
| Coach: Del Bosque | |
| Player | Bookings |
|---|---|
| F. Muslera | |
| D. Lugano | |
| M. Pereira | |
| M. Cáceres | |
| D. Godín | |
|
D. Pérez
|
56'
|
|
C. Rodríguez
|
32'
|
|
Á. González
|
|
|
N. Lodeiro
|
|
| L. Suárez | |
|
E. Cavani
|
|
| Coach: Ó. Tabárez | |
| Player | Bookings |
|---|---|
|
for Mata 46' |
|
|
for Puyol 46' |
|
|
for Iniesta 60' |
|
|
for Cazorla 71' |
|
|
for Pedro 75' |
|
|
for Jordi Alba 78' |
|
| Player | Bookings |
|---|---|
|
for D. Pérez 65' |
|
|
for C. Rodríguez 69' |
|
|
for E. Cavani 70' |
|
|
for N. Lodeiro 77' |
|
|
for Á. González 80' |
|
GOAL.COM - Global football news, transfer rumours and betting editorial
Soccer news, results, live scores, football transfer rumours and fixtures - Goal.com
