Gordon Strachan has a strong squad at his disposal for his first match since taking over the role. A host of Premier League names, including Charlie Adam and Steven Fltecher are set to feature.
Celtic midfielder Scott Brown has been named captain but club team-mate James Forrest will not be selected after his manager opted to rest him.
The ex-Middlesbrough boss has an exciting set of striking options from which to choose despite Ross McCormack's withdrawal through illness - with Fletcher, Jordan Rhodes and Kenny Miller all battling for starting berths.
As for the visitors, Tarmo Ruutli has named a mixture of veteran and inexperienced players for the match. In particular, he has plenty of experience in defence with Dmitri Kruglov, Ragnar Klavan and Enar Jaager having made more than 80 appearances for their country.
Motherwell striker Henrik Ojamaa is likely to have to settle for a place on the bench with Andres Oper and Tarmo Kink filling the two striking spots.
Scotland currently sit 69th in Fifa's latest world rankings. Their highest-ever rating was back in October 2007 when they were listed 13th.
New boss Gordon Strachan (pictured right) scored five times in 50 caps for Scotland during his playing days.
The country's joint-top scorers are Kenny Dalglish and Denis Law on 30 apiece, with Kenny Miller the closest of the current squad with 17 goals to his name. Miller is 9/2 with Paddy Power to score the last goal in this game.
Estonia have won two of their last six matches - a 1-0 World Cup 2014 qualification win over Andorra and a 2-1 victory against Oman in a friendly.
They currently occupy 83rd spot the Fifa rankings, having previously risen as high as 47th back in March 2012.
Martin Reim is Estonia's most-capped player - making 157 appearances and scoring 14 times between 1992-2009.
|Coach: G. Strachan|
for S. Maloney 46'
for C. Burke 46'
for S. Brown 62'
for C. Adam 62'
for S. Fletcher 67'
for S. Naismith 74'
|Klopp predicts tough Hertha battle|
|Dempsey has medical ahead of Fulham return|
|Bruce sympathetic to Mackay situation|
|A-League: Brisbane Roar 0 Newcastle Jets 2|
|Celtic´s Lustig set to miss four months|
|Messi blasts Barca official|
|Redknapp slams Villas-Boas´ signings|
|Atalanta out to continue home record|
|Phillips poised for January Palace exit|
|Dembele: Spurs ´positive´ about Sherwood appointment|
|Benitez predicts busy January at Napoli|
|Kerslake expects Mackay to be in charge for Liverpool game|
|Lowe given Glory role|
|Baines set for Everton return|
|Pedro keen on emulating Iniesta|
|Pochettino not interested in January purchases|
|Poyet calls for mid-season break|
|Iajour up for Bayern test|
|Martinez seeking ´short-term solutions´ in transfer window|
|Kompany urges City to remain focused|
|Rodgers glad he avoided Tottenham|
|Del Piero in line to take on Juventus in Australia|
|Copa del Rey Wrap: Valencia scrape through, Bilbao thrash Celta|
|Primeira Liga: Maritimo 2 Braga 2|
|Galliani to stay at Milan|
|Klopp plays down Club World Cup|
|Schalke coach Keller not fearing the sack|
|Wilshere loses appeal against two-match ban|
|Zaha on Pardew´s radar|
|Milan will be my final club, says Abbiati|
|Anigo to remain at Marseille helm for time being|
|Premier League Preview: West Brom v Hull City|
|No Bankia involvement in Bale deal, says Perez|
|Galliani wants stronger Milan youth system|
|Rafinha extends Bayern contract|
|Premier League Preview: Stoke City v Aston Villa|
|Poyet: No excuse not to perform|
|Vanishing spray to be used at World Cup|
|Gabbidon praises Palace strike pair|
|Premier League Preview: Manchester United v West Ham|
|Hughton calls for Norwich City to show character|
|Premier League Preview: Fulham v Manchester City|
|Samaras attracting Lazio interest|
|Premier League Preview: Liverpool v Cardiff City|
|Rodgers backs Mackay at Cardiff|
|Foster back fit and raring for West Brom recall|
|De Boer agent denies Tottenham contact|
|Premier League Preview: Crystal Palace v Newcastle United|
|Hungary appoint Pinter as new coach|
|Iniesta signs new Barca contract|
|Rodgers coy over Suarez talks|
|Jagielka hopes for fresh faces at Everton to help top-four push|
|A-League: Central Coast 1 Wellington 0|
|Spain end top of FIFA rankings for sixth year running|
|Allardyce disappointed to draw Manchester City|
|Pascoe hails ´unbelievable´ Suarez|
|Vorm knee surgery brought forward|
|Blanc hails Cavani brace|
|Michu wants Aspas to join Swansea City|
|Hoeness plays down Bayern treble suggestions|
|Dzeko confident he can fill Aguero void|
|Moyes: No loan offers for Zaha|
|Kiessling calls for Leverkusen response|
|Matuidi: Cavani on par with Ibrahimovic|
|Yeboah set to join Borussia Monchengladbach|
|Rooney a ´chance´ to face West Ham|
|FIFA Club World Cup Preview: Bayern Munich v Raja Casablanca|
|Benzarti praises ´extremely talented´ Raja Casablanca|
|Ranieri unsure over Falcao return|
|Coupe de La Ligue Wrap: Cavani leads PSG to dramatic win|
|Copa del Rey Wrap: Real Madrid through as Sevilla crash out|
|Tottenham job appeals to Sherwood|
|Sherwood gutted after defeat|
|Hughes: United worthy winners|
|Moyes pleased to see United weather storm|
|Allardyce hails West Ham fight|
|Coppa Italia: Juventus 3 Avellino 0|
|Manchester clubs kept apart in League Cup semi draw|
|League Cup: Tottenham 1 West Ham 2|
|League Cup: Stoke City 0 Manchester United 2|
|FIFA Club World Cup: Raja Casablanca 3 Atletico Mineiro 1|
|Sheffield Wednesday, Wigan abandoned due to heavy rain|
|United face anxious Rooney wait over injury|
|Messi making good progress|
|Ramos ban overturned|
|Osvaldo charged by FA|
|In-demand Ince offered new Blackpool deal|
|Molde confirm Solskjaer approaches|
|Kramer keen to continue home record|
|Rodgers: Henderson has potential to get even better|
|Ruiz on Anderlecht´s radar|
|Swansea, Hull fined by FA over player behaviour|
|Leeds keen on re-signing Gradel|
|Leverkusen announce Ryu deal|
|Ribery named Bundesliga Player of the Year|
|Moyes: No Zaha interest|
|Barcelona, Real Madrid in European Commission investigation|
|Basel: No Tottenham approach for Yakin|
|Chelsea set for Guarin bid, agent claims|
|Lewandowski has Dortmund goal concerns|
|Pogba, Pirlo will not sign before Christmas, says Marotta|
|Guardiola convinced to join Bayern after ´meat´ and greet|
|Martinez: Everton seen as a ´perfect´ loan destination|
|Anderlecht ´perfect´ for Defour, says Van Holsbeeck|
|Watford appoint Sannino|
|Sakho feels ´lucky´ to play with Suarez|
|Lippi: Too many teams competing in Club World Cup|
|Moyes ´told Welbeck to learn from Rooney´|
|I would kill myself over match-fixing, says Gattuso|
|Hughes dismisses calls for Januzaj protection|
|Aguero ´could miss up to two months´|
|Guardiola lauds Ballon d´Or nominee Ribery|
|Liverpool open Suarez contract talks|
|Copa del Rey Wrap: Barcelona, Levante cruise through|
|A-League Preview: Derby date beckons for winless Heart|
|Pearson upbeat despite Leicester defeat|
|Poyet urges Sunderland to build on Chelsea win|
|Mourinho rues missed chances|