A rare Zeljko Filipovic goal helped Maribor beat Wigan Athletic 2-1 to progress into the UEFA Europa League knockout stages.
Zulte Waregem's 2-0 defeat against Group D winners Rubin Kazan coupled with Maribor's victory sent the Slovenian champions into the round of 32 in what ended up being a winner-take-all clash on Thursday with the English FA Cup holders.
Filipovic's first goal for the club since July 2012 proved to be the difference after Jordi Gomez had put Wigan in front from the penalty spot after 41 minutes.
But Wigan's first away goal in the competition in their debut European season was cancelled out almost immediately by Dejan Mezga.
Both teams were reduced to 10 men – Chris McCann and Ales Mertelj were given their marching orders – before Filipovic's strike and two late goals in the other Group D fixture in Brugge added to the drama and ensured that Maribor avoided a third consecutive exit at the group stages having started the evening bottom.
Defeat for Wigan in new manager Uwe Rosler's first game in charge represented the sixth successive loss in all competitions for the Championship club.
Filipovic gave Wigan an early scare after seven minutes with the first chance of a cagey opening after he was afforded plenty of time and space 20 yards out before crashing a rising shot that flashed wide and had goalkeeper Scott Carson scrambling for his top left-hand corner.
Nick Powell, who netted a brace in Wigan's 3-1 win in the first meeting between the two sides in October, volleyed over from just outside the penalty area after collecting Jean Beausejour's bobbled pass.
Gomez triggered a frantic final 10 minutes of the first half when he saw his 20-yard free-kick rebound to safety off the post after being felled by Marcos Tavares.
The Spanish midfielder did find a way past goalkeeper Jasmin Handanovic , though, four minutes before the interval from the penalty spot.
Arghus was slow to react to Gomez's pass and Powell nipped in to prod the ball away from goal and draw a clumsy challenge from the Brazilian defender.
Gomez sent the subsequent spot-kick straight down the middle, sparking wild celebrations among Wigan's travelling fans that quickly turned to despair as Maribor levelled less than two minutes later.
Mitja Viler's shot glanced against McCann's arm and referee Szymon Marciniak was quick to point to the spot again and give the former Burnley midfielder his marching orders for a second bookable offence.
Carson did superbly to get down low to his right and palm Mezga's effort against the post, but he was powerless to prevent the penalty taker from tucking away the rebound from inside the six-yard box.
Powell turned Beausejour's cross wide five minutes after the restart as the visitors initially responded well to going down to 10 men before Filipovic put Maribor ahead with a fantastic strike just before the hour.
Mezga's cut-back fell invitingly for Slovenia international Filipovic and he coolly dispatched a side-footed effort from 25 yards that nestled in Carson's top left-hand corner.
Mertelj was then sent off with 16 minutes remaining for a rash tackle on Gomez, earning his second yellow card, and Handanovic kept out a late Marc-Antoine Fortune effort as Maribor progressed in dramatic style.
|8||D. Mezga||43' 43'|
|70||A. Mertelj||65' 74'|
|Coach: A. Šimundža|
for Marcos Tavares 78'
for D. Mezga 81'
for N. Fajić 86'
|Portland Timbers 1 San Jose Earthquakes 0: Jewsbury wins it in stoppage time|
|No move yet for Van Persie|
|Lloyd wins Golden Ball, Silver Boot awards|
|Mascherano: I never grabbed Banega|
|Dunga requested Brazil not appeal Neymar´s suspension|
|United States 5 Japan 2: Lloyd stars with hat-trick|
|Fiorentina deny Inter criticism|
|Nani relishing Fenerbahce opportunity|
|Newcastle hold talks over Northampton youngster|
|Cuadrado´s agent plays down Chelsea exit rumours|
|Liverpool´s Alberto set for Deportivo loan|
|Leverkusen suffer surprise defeat, Stuttgart hit six|
|Inter ´dismayed´ at Fiorentina vice-president´s Salah Twitter outburst|
|Blaszczykowski ruled out of Dortmund´s Asia tour|
|Gerrard gets the beers in for LA Galaxy fans|
|De Gea coy over Real links|
|Former Brazil star Carlos handed Delhi reins|
|Ciftci will not push through Celtic switch – agent|
|In-demand Mitrovic considering Roma offer|
|Lehmann calls on Cech to ´get over´ Chelsea|
|Marlos double sinks Monaco|
|Mauritius 0 South Africa 2 (agg 0-5): Bafana set up Angola qualifier|
|Keane relishing Gerrard arrival|
|Palace confirm Cabaye interest|
|Hamburg bring in Spahic after head-butt ban|
|Blatter hits out at France and Germany over World Cup votes|
|Sanchez: World Cup exit spurred Chile to Copa glory|
|Jojic makes Cologne switch, Santana move falls through|
|Carrillo keen to get going at Monaco|
|Micronesia thrashed 38-0 as Fiji triumph in Olympic qualifier|
|Schalke stunned by ´machine´ Caicara|
|MLS Review: Keane shines at Gerrard´s Galaxy unveiling|
|Counter-attacking the key for Japan|
|Jimenez happy at Atletico|
|Gerrard predicts ´successful future´ with Galaxy|
|Iniesta can´t see Real selling Ramos|
|Keshi sacked as Nigeria coach|
|Three finals, three defeats for Messi, Mascherano|
|Nani close to Fenerbahce move|
|Sampaoli revels in ´unbelievable joy´|
|Bravo: Copa victory a dream|
|Martino: Argentina should have won|
|Chile 0 Argentina 0 (4-1 on penalties): Hosts end trophy drought|
|Germany 0 England 1 (after extra time): England make World Cup history|
|Kenya 0 Ethiopia 0 (agg 0-2): Hosts sent out of CHAN qualifiers after second penalty miss|
|Dortmund put 17 past Olympians, Bremen hand out thrashing|
|Dinamo Zagreb confirm arrests of coach and club president|
|I didn´t know who Wimbledon guest Klopp was - Brown|
|LeBron James backs Liverpool captain Henderson for FIFA 16 cover.|
|Ramos: I am not negotiating with anyone|
|Valencia complete Mina swoop|
|United States v Japan: US seek final redemption|
|Hanousek consigns Celtic to defeat|
|Roma confirm Dzeko interest|
|Arsenal forward Podolski completes Galatasaray switch|
|Warm Dortmund welcome delights Tuchel|
|Silva vows to fight for Madrid place|
|Mancini hints at Shaqiri and Santon departures|
|Bojan raring to go after return from injury|
|Babel backs Firmino to shine at Liverpool|
|Falcao must wait to impress, warns Chelsea favourite|
|Bartomeu: Deal in place for Turan|
|Parejo re-signs with Valencia|
|MLS Review: Sounders return to winning ways|
|Klinsmann unhappy with USA performance|
|High hopes for Paraguay - Diaz|
|Gareca: More to come from Peru|
|Gerrard had European offers|
|Argentina out to spoil Chile´s party - Martino|
|Sampaoli: Chile won´t change style|
|Di Maria will come good at United - Rojo|
|Peru 2 Paraguay 0: Gareca´s men finish third at Copa|
|United States 4 Guatemala 0: Klinsmann´s men win comfortably|
|´I’d prefer no-one to know my name´ - Bassett|