Newcastle United will hope to build on last week's win at Manchester United as they host Alan Pardew's former club Southampton on Saturday.
Yohan Cabaye scored the only goal of the game as the north-east club beat United in their own backyard for the first time since 1972.
Newcastle have now won five of their last six Premier League games and will be striving for a fourth consecutive win at St James’ Park when Southampton make the long journey north.
Pardew was sacked by Southampton when they were in League One three years ago and the 52-year-old is expecting a stern test against his former employers.
He said: "We’ve had a really strong period and it’s important we focus on this game.
"There is a huge significance in this result. Southampton are a good side, very similar to ourselves in that they are set up to attack, it should be a cracker.
"We didn’t slip up against Norwich and West Brom, and this is a game we’re really looking forward to."
France midfielder Cabaye will not feature against Mauricio Pochettino's side after picking up his fifth booking of the season against United.
Mathieu Debuchy has recovered from a dead leg sustained at Old Trafford, so Ryan Taylor (knee) is their only other absentee.
St James' Park has not been a happy hunting ground for Southampton, as they have not won there since 1997.
Newcastle have won nine of their last 10 home games against Southampton and Pochettino's men have failed to win on the road since their 1-0 victory at Liverpool in September.
The St Mary's Stadium club managed to stop the rot with a 1-1 draw against Manchester City last weekend as Pablo Daniel Osvaldo scored his second goal in as many games and they will replace Newcastle in seventh place with a win on Saturday.
Pochettino said: "Newcastle are a team who have - in the last few weeks - been playing well.
"They are a physical, strong, aggressive side who are tough to beat. We are aware what we're up against."
Pochettino revealed Morgan Schneiderlin (groin) could play some part, but the midfielder is not fit enough to play the whole game.
Nathaniel Clyne (hamstring), Victor Wanyama (leg), Artur Boruc (hand), Kelvin Davis (back), Danny Fox (hamstring) and Guly Do Prado (knee) are definitely out.
|Coach: A. Pardew|
for Shola Ameobi 61'
for Y. Gouffran 72'
for D. Santon 78'
|Champions League Final: Luis Enrique worried about Juve, Italian fan nears end of Berlin bike ride|
|Essien joins Panathinaikos|
|Blatter in profile: A look back on 17 years at the top of world football|
|Demichelis set for international retirement after Copa|
|Football world reacts to Blatter resignation|
|Blackpool turn to McDonald|
|Blatter resignation: How the FIFA scandal unfolded|
|Ancelotti rejects Milan approach|
|Platini: Blatter resignation ´the right decision´|
|Swiss Attorney General: Blatter not under investigation|
|Blatter resignation can inspire FIFA change - Scala|
|Mohsni faces lengthy SFA ban|
|Sepp Blatter: Resignation speech in full|
|Blatter to resign as FIFA president|
|Adkins named Sheffield United manager|
|Juve talks ongoing - Witsel|
|Costa has no intention of leaving Chelsea|
|Ligue 1: Paris Saint-Germain season review - Blanc´s men make history|
|Luis Enrique ´worried´ by Juve|
|Mourinho: Costa happy at Chelsea|
|Mourinho hits out at ´unacceptable´ Loftus-Cheek display|
|Inter an ´option´ for Richards|
|Messi: Off-field relationship with Neymar and Suarez key|
|Remy rifle seals Sydney win for Chelsea|
|Messi could replicate Bilbao goal - Luis Enrique|
|Liverpool mauling a boost in transfer market, says Stoke chairman Coates|
|Adkins: Football can learn a lot from rugby|
|Celtic swoop for City defender Boyata|
|Xavi out to sign off in style at Barca|
|Criscito and Poli leave Italy squad|
|Lacazette plays down ´unfounded´ PSG rumours|
|Lloris: No buy-out clause in Tottenham contract|
|Newcastle released Taylor and Gutierrez in same phone call|
|Alba signs new Barcelona deal|
|Benteke coy on Villa future|
|FIFA denies Valcke involvement in $10million payment|
|Brazil selection never influenced, says technical director|
|Pogba doing ´great things´ and will get better, says Deschamps|
|Bundesliga: Borussia Dortmund season review - Klopp endures rocky farewell|
|Adler ´aged three years´, Labbadia ´extremely proud´ of Hamburg|
|Colombia squad settles in Argentina|
|Balotelli ´a target´ because of Liverpool form - Richards|
|Bosnich: If I´d listened to Terry I would have avoided drugs|
|Luiz Gustavo ruled out of Brazil´s Copa America squad|
|Mexico confirm Copa squad|
|Pogba ´very happy´ at Juve|
|Pogba can be Europe´s greatest - Pirlo|
|Pinedo stays in Argentina, Bolivia captain Raldes in Copa America squad|
|Quinteros cuts Banguera, Hidalgo for Chile showpiece|
|Injured Gonzalez misses Copa America, Venezuela finalise youthful squad|
|Champions League Final: Buffon plays down Juve hopes, Iniesta doubtful|
|Karlsruher 1 Hamburg 2 (2-3 agg): Muller strike ensures survival|
|CONCACAF official Sanz banned by FIFA|
|Gourvennec shuns admirers with Guingamp extension|
|Pastore signs PSG extension|
|Morel swaps Marseille for Lyon|
|Watford sign Austria defender Prodl|
|Monaco confirm Berbatov departure|
|Peru v Mexico: Herrera confident as Copa preparations continue|
|Injury rules Dost out of Netherlands friendlies|
|Koeman must strengthen attack for Europa League challenge - McMenemy|
|Wilshere apologises for Spurs taunts|
|Marchisio: No fear ahead of Barcelona clash|
|Klopp to take break after leaving Dortmund|
|Champions League win would be ´more than extraordinary´ - Allegri|
|Charity calls for education after Leicester ´racist orgy´ claims|
|Taylor agrees Swansea deal|
|Sevilla snare Krohn-Dehli|
|Coloccini hails Gutierrez after ´perfect´ Newcastle finale|
|Benitez excited by Madrid opportunity|
|Sampaoli confirms final Chile squad for Copa America|
|Clement ready to go it alone at Derby|
|Mihajlovic confirms Sampdoria exit|
|Brentford turn to Dijkhuizen|
|Usami, Moto to lead Japan qualifying threat|
|Vieira ´the best bet´ for Newcastle - Bernard|
|´We´ll see what happens with my future´ - De Gea|
|Klinsmann: Guzan will start at Gold Cup|
|Alves wants Barca extension not PSG - Blanc|
|Derby appoint Paul Clement as head coach|
|Karlsruher ´can only win´ - Kauczinski|
|Ronaldinho causes stir with disallowed goal|
|Szczesny plans Arsenal stay|
|Pioli: Lazio deserve Champions League qualification|
|Pablo Aimar makes River Plate return|
|MLS Review: Seattle leave it late against Red Bulls|
|Wenger: Arsenal won´t spend big|
|Police to investigate Rangers-Motherwell fight|
|´I will definitely stay´ at City - Toure|
|Champagne backs Blatter to reform FIFA|
|Honduras 2 El Salvador 0: Penalty, goal and red card to Lozano|
|Mancini wants Icardi to stay|
|Sampdoria set to speak on Mihajlovic future|