Porto head to Atletico Madrid on Wednesday knowing only victory will give them a chance of progressing in the UEFA Champions League.
The Portuguese club currently sit one point behind Zenit St Petersburg in Group G, but the head-to-head record between the sides means that Paulo Fonseca's men need to pick up three points and hope Zenit fail to beat Austria Vienna.
Atletico are already through to the knockout stages, having won four out of four prior to a 1-1 draw at Zenit last time out.
It was the Spanish club who came out on top when these sides met in Portugal on October 1 - Diego Godin and Arda Turan finding the net in a 2-1 victory.
La Liga's second-placed club have won nine successive games at home since being held to a 1-1 draw by Barcelona in the first leg of the Spanish Super Cup in August.
They have also won 16 of their last 19 fixtures in all competitions, aided by striker Diego Costa, who has netted 15 goals in as many league appearances.
Porto, meanwhile, have endured a disappointing Champions League campaign so far.
A tally of one point from three home games represents their worst return in the competition.
Porto’s 53-match unbeaten run in the Primeira Liga also came to an end recently, with a 1-0 defeat at Academica on November 30.
The reigning Portuguese champions had won 42 and drawn 11 during their terrific sequence of results.
Both Porto and Atletico enjoyed victories in their most recent domestic fixtures, with the former overcoming Braga 2-0 in the league and Atletico hammering Sant Andreu 4-0 in the Copa del Rey.
Nabil Ghilas recovered from a muscle problem in time to appear on the bench for Porto on Saturday and could feature this time around.
Atletico will be without Juanfran, who is serving a one-game ban.
|Coach: D. Simeone|
for Diego Costa 46'
for Óliver Torres 62'
for Adrián 82'
|Relegation run-in favours Leicester - Walsh|
|Fiorentina v Dynamo Kiev: Pasqual calls for response in second leg|
|Schmidt extends Mainz deal|
|Parma on the market for €20million|
|Zenit v Sevilla: Villas-Boas wary despite key player returns|
|Title a step too far for United, says Evans|
|De Bruyne agent reveals Manchester City talks|
|Kroos not making excuses about absences|
|BREAKING NEWS: Smalling signs new United deal|
|Depay like a young Ronaldo - De Boer|
|Napoli v Wolfsburg: Benaglio eyes return to form|
|Frontzeck: Survival fight is not about me|
|Real can cope with injuries - Ancelotti|
|Dnipro v Club Brugge: Preud´homme prepares to show his hand|
|Silva returns to training after cheekbone scare|
|Villa and Reading charged over alleged FA Cup crowd trouble|
|Zeman resigns from Cagliari post|
|Opportunity knocks as Dyche plans for Barnes absence|
|Berbatov dreaming of Champions League semi-final|
|Benzema joins Real´s injury list|
|Jenkinson: West Ham will not settle for mid-table|
|Montella calm over fan frustrations|
|Blanc: Barca are the model for PSG|
|Newcastle just need three more points - Janmaat|
|Gaya: Six finals left for Valencia|
|Muller wary of Porto counter-attacks|
|Bartomeu plays down Pogba link|
|Verratti hails ´essential´ Ibrahimovic|
|Zidane backs PSG to upset Barca|
|America v Montreal Impact: Klopas unfazed by host´s form|
|Vlaar open to Villa stay|
|Shepherd urges fans not to boycott Newcastle|
|Maritimo 1 Nacional 1: Tiquinho ensures derby finishes all square|
|Fiorentina 0 Verona 1: Diamanti and Neto pay the penalty|
|Elche 1 Real Sociedad 0: Bergara gifts win to hosts|
|Van Persie returns in Under-21 game|
|Turkish Super Lig Review: Galatasaray slip sees Fenerbahce go top|
|Russian Premier League Review: Arsenal Tula and Rostov maintain survival bids|
|Frontzeck named as Korkut´s replacement at Hannover|
|Lopetegui wary of Bayern backlash|
|Pastore plays down Cantona´s world best tag|
|PSG absences no excuse for failure - Blanc|
|Suarez sad to see Gerrard leaving Liverpool|
|Cleber injury adds to Hamburg woes|
|Northern Ireland free to play Romania at Windsor Park|
|Juve sweating on Vidal availability|
|Monaco v Juventus: Evra ready to take control|
|Striking concerns for Chelsea after Drogba injury|
|PSG and Chelsea have bid for Dybala, claims agent|
|Pogba can leave Juve for ´right offer´|
|Bendtner dropped after arriving late for training|
|Messi achievement unrepeatable, says Luis Enrique|
|Football League Preview: Preston and MK Dons battling to join Bristol City|
|Real Madrid v Atletico Madrid: Ancelotti optimistic amid injury concerns|
|Iniesta declared fit for PSG second leg|
|Bale remains a doubt for Atletico clash|
|Schweinsteiger set to face Porto, Ribery to miss out|
|No broken cheekbone for Silva|
|Final appearance can remove negativity at Villa - Fox|
|Bale selected in Football League Team of the Decade|
|PSV director: United and PSG want Depay|
|Korkut sacked by relegation-threatened Hannover|
|Sherwood: Pressure all on Arsenal|
|Newcastle in a ´dangerous moment´ - Colback|
|Kovac hopes to have Modric fit for Euro qualifier|
|Copa Libertadores Preview: Cruzeiro boss Oliveira does not fear sack|
|MLS Review: Revs extend unbeaten run, Timbers stun City|
|Fournier proud and disappointed|
|Shaw ready to make an impact|
|Hazard among best three in the world - Mourinho|
|Carver: Newcastle are in relegation battle|
|CAF Champions League Review: Setif get two away goals, Al Ahly denied late on|
|Inzaghi praises Milan derby officials|
|La Liga Review: Granada frustrate Sevilla, Villarreal´s woes continue|
|Inter should have had a penalty, Mancini fumes|
|Ligue 1 Review: Lyon return top after derby draw|
|Inter 0 Milan 0: Disappointing derby ends in stalemate|
|Primeira Liga Review: Sporting made to battle, Penafiel running out of time|
|Balotelli targets officials in latest social media outburst|
|Bundesliga Review: Werder Bremen edge Nordderby, De Bruyne rescues Wolfsburg|
|Serie A Review: Napoli close on stumbling Roma|
|Pochettino congratulates 30-goal Kane|
|Rodgers questions Liverpool´s mental strength|
|Carver counting on experience after latest defeat|
|Sherwood marvels at Grealish potential|
|Eredivisie Review: Dordrecht relegated as Go Ahead Eagles stun Feyenoord|
|Newcastle United 1 Tottenham 3: Losing streak continues amid fan boycott|
|Kouyate elbow on Silva accidental - Allardyce|
|Aston Villa 2 Liverpool 1: Delph ends Gerrard´s hopes of dream farewell|
|Pellegrini hails City response to derby defeat|
|Silva back home after Kouyate elbow|
|Manchester City 2 West Ham 0: Silva injury sours routine win|
|Bayern Munich v Porto: Neuer rallies Germans for uphill battle|
|Barcelona v Paris Saint-Germain: Marquinhos keeps the faith ahead of Camp Nou test|
|Fer closes in on QPR return|
|Crouch set for surgery|
|Dortmund confirm Tuchel as Klopp replacement|
|Adams leaves relegation-threatened Tranmere|
|Real still unsure over Modric injury|
|Tevez rubbishes Juve exit talk|
|Moyes: I had to fight to keep Rooney at United|
|Perth Glory 3 Melbourne City 1: Maclaren treble the difference|
|Dyche: Burnley are too honest|
|Illarramendi eager for Real stay|
|Hazard issues Chelsea warning|
|MLS Review: Injury-time winner buoys Galaxy, Martins shows class for Sounders|
|Pastore talents ´unpredictable´ - Blanc|
|Liverpool much bigger than City - Rodgers|
|AFC Champions League Preview: Evergrande look to progress|
|Clarke expects distraught Federici to bounce back|
|Toure is City´s scapegoat - agent|
|Allegri praises high-flying Juve|
|Athletic Bilbao 4 Getafe 0: Hosts end winless run|