Porto head to Atletico Madrid on Wednesday knowing only victory will give them a chance of progressing in the UEFA Champions League.
The Portuguese club currently sit one point behind Zenit St Petersburg in Group G, but the head-to-head record between the sides means that Paulo Fonseca's men need to pick up three points and hope Zenit fail to beat Austria Vienna.
Atletico are already through to the knockout stages, having won four out of four prior to a 1-1 draw at Zenit last time out.
It was the Spanish club who came out on top when these sides met in Portugal on October 1 - Diego Godin and Arda Turan finding the net in a 2-1 victory.
La Liga's second-placed club have won nine successive games at home since being held to a 1-1 draw by Barcelona in the first leg of the Spanish Super Cup in August.
They have also won 16 of their last 19 fixtures in all competitions, aided by striker Diego Costa, who has netted 15 goals in as many league appearances.
Porto, meanwhile, have endured a disappointing Champions League campaign so far.
A tally of one point from three home games represents their worst return in the competition.
Porto’s 53-match unbeaten run in the Primeira Liga also came to an end recently, with a 1-0 defeat at Academica on November 30.
The reigning Portuguese champions had won 42 and drawn 11 during their terrific sequence of results.
Both Porto and Atletico enjoyed victories in their most recent domestic fixtures, with the former overcoming Braga 2-0 in the league and Atletico hammering Sant Andreu 4-0 in the Copa del Rey.
Nabil Ghilas recovered from a muscle problem in time to appear on the bench for Porto on Saturday and could feature this time around.
Atletico will be without Juanfran, who is serving a one-game ban.
|Coach: D. Simeone|
for Diego Costa 46'
for Óliver Torres 62'
for Adrián 82'
|Wenger criticism baffles Redknapp|
|Leicester must strengthen in window - Walsh|
|United not title contenders - Docherty|
|Koeman: Southampton youngsters will get a chance|
|Dyche empathises with Liverpool striker crisis|
|Cagliari turn to Zola|
|Rooney thanks Van Gaal for Christmas break|
|Cruzeiro offer Paulinho Tottenham exit chance|
|Carlisle´s wife grateful to Burnley|
|Katebe called up to Zambia AFCON squad|
|Cape Verde name AFCON squad|
|Finke names much-changed Cameroon squad|
|Grant omits World Cup troublemakers for AFCON|
|Blackpool striker Ranger goes AWOL|
|Allardyce relishing Mourinho meeting|
|Ashley fails to increase Rangers stake|
|Crystal Palace v Southampton: Koeman calls for focus|
|Warnock targeting striker in January|
|Chelsea v West Ham: Adrian vows visitors will attack|
|Heskey signs short-term deal at Bolton|
|Everton v Stoke City: Martinez eyes strong form|
|Juninho defends David Luiz|
|Burnley v Liverpool: Dyche defends Rodgers ahead of Turf Moor test|
|Arsenal v QPR: Wenger eyes festive momentum|
|Liverpool are growing in confidence, says Rodgers|
|Redknapp: Austin future could depend on survival|
|Martinez wants Everton consistency|
|Barca want Neymar until 2020, says agent|
|Jones undeterred by pressure of Liverpool starting role|
|Allardyce ´knows how to beat managers´ - Carroll|
|Jones playing for a new contract|
|China select Evergrande spine for Asian Cup|
|A-League Preview: Koren tips City to build|
|Khedira keen to fight for Real spot|
|Southampton confirm Elia deal|
|Cellino to remain as Leeds owner until after appeal|
|Manchester United v Newcastle United: Van Gaal demands domination|
|Van Gaal refuses to dismiss Bale speculation|
|Sunderland v Hull City: Bruce sure of Hull revival|
|Swansea City v Aston Villa: Lambert optimistic of away success|
|Agbonlahor red rescinded|
|Falcao depends on team-mates to perform - Van Gaal|
|Monk dismisses talk of Gomis move|
|West Brom v Manchester City: Pellegrini to experiment again|
|Xavi: I was ready for New York switch|
|Ibrahimovic fumes at awards snub|
|Irvine: No approaches for Berahino|
|Pearson determined to revive Leicester fortunes|
|League Two Preview: First host third as Wycombe meet Luton|
|League One Preview: Buoyant MK Dons eye more glory, Bristol City seek response|
|Championship Preview: Pritchard plotting to end Ipswich run, Bournemouth host Fulham|
|Kaboul place not guaranteed by captaincy - Pochettino|
|Koeman hopeful of Elia deal|
|Atletico president not ruling out Torres return|
|Swansea secure Oliveira signing|
|No excuses for Pellegrini|
|Walcott pace unaffected by injury|
|Former Real Madrid star Roberto Carlos backs Ronaldo for Ballon d´Or|
|Former PFA chairman Carlisle ´stable´ after serious incident|
|Balotelli remorse saved him from longer ban|
|Bayern midfielder Martinez ´on track´ with rehab|
|Pardew ´overjoyed´ at Gutierrez return|
|Spurs confirm Yedlin to join in January|
|Zeman sacked by Cagliari|
|Casillas: I´m going nowhere|
|Bruce demands McShane apology|
|Pulis would welcome Brighton talks|
|Buffon: Juve angry after Supercoppa loss|
|Arteta out until new year|
|Rangnick: Kampl deserves Dortmund switch|
|PFA offers support to Carlisle after serious incident|
|Napoli can mount title bid - Higuain|
|Cech´s agent urges Liverpool and Arsenal to make bid|
|Hart happy to be back to his best|
|Terry thrilled with ´revelation´ Matic|
|Perez rues ´unfair´ Tyne-Wear derby result|
|Khalfan Ibrahim returns from injury|
|Magath slams ´sensitive´ Fulham|
|´Limited´ attacking options inspire Postecoglou´s selections|
|Carlisle reportedly involved in serious incident|
|Primeira Liga Review: Braga leapfrog Guimaraes|
|Hughes upbeat despite Stoke defeat|