Barcelona lead Atletico Madrid at La Liga's summit by just goal difference after they were stunned 1-0 by Athletic Bilbao on Sunday.
Atletico's 2-0 success at Elche on Saturday meant that Barcelona needed to win to restore their three-point advantage.
But they lost for the second outing in a row – something they have done just three times in the last four years – thanks to Iker Muniain's goal in the 70th minute.
Muniain missed a good chance in the first half, scuffing into the arms of Barcelona goalkeeper Jose Manuel Pinto, while Neymar had several attempts for the losers.
Bilbao's incessant work-rate and pressing paid dividends though, as Markel Susaeta's cross from the right was converted by Muniain.
They nearly went two goals down when Pinto was forced into a superb reflex save to deny Gaizka Toquero's header.
And Barcelona struggled to create in the latter stages as Bilbao held on for a victory that takes them up to fourth.
Valencia climbed to ninth after Jonas struck a hat-trick in their 3-0 home success against a 10-man Osasuna.
Fresh off a 1-0 UEFA Europa League win at Swansea City on Thursday, Valencia were handed a big advantage when Patxi Punal was given a straight red card in the 17th minute.
And Brazilian Jonas took full advantage, first scoring in the 45th minute to delight the Mestalla crowd who had not seen their side win a home league fixture since September.
Jonas doubled his account three minutes after half-time, before completing his hat-trick in the 53rd minute.
Sunday's other matches saw Sevilla win 2-1 at Granada thanks to Kevin Gamiero's late strike.
Yacine Brahimi cancelled out Carlos Bacca's opener with a second-half penalty, but Sevilla had the last laugh as substitute Gameiro netted with three minutes left.
And Real Betis remained on the bottom of the league after they were held to a 2-2 home draw against Rayo Vallecano.
Real Betis led twice but lost two points in the 91st minute, as Bueno's second clawed the visitors level.
|Coach: Ernesto Valverde|
|Peru Primera Division Review: Inti Gas go top, Universitario lose|
|Klose to decide on Germany future|
|Ecuador Primera A Review: Emelec poised for championship|
|Devastated Messi: Golden Ball not important|
|Messi comparison inspired Gotze, says Low|
|Hummels: I´m on another planet|
|Messi named player of the tournament|
|Sabella proud of players, defends Messi|
|Adebayor contracts malaria, out of US tour|
|Lahm ecstatic after World Cup triumph|
|Newcastle complete Cabella deal|
|Mascherano endures World Cup pain|
|2014 FIFA World Cup Final: Player Ratings|
|2014 FIFA World Cup Final: Where the final was won and lost|
|2014 FIFA World Cup Final: New Germany ready to dominate|
|2014 FIFA World Cup Final: Germany 1 Argentina 0 (after extra time)|
|BREAKING NEWS: Germany win World Cup|
|Rousseff thanks Brazil despite World Cup woe|
|Fred ´finished´ with Brazil|
|Manchester City lose to Dundee in pre-season opener|
|Rami keen to restore Milan glories|
|Thai Premier League Review: Muang Thong win again, BEC Tero Sasana pay penalty|
|In-demand Lovren joins Southampton on tour|
|Adidas to stick with Suarez|
|Cesar accepts Brazil career all but over|
|Rodriguez signs new Fiorentina deal|
|UEFA Champions League Preview: Celtic begin campaign, Steaua in Norway|
|K.League Review: Steelers maintain lead as top four all win|
|Suso eager for Liverpool stay|
|McDonald allays West Ham injury fears|
|Basanta urges Argentina to enjoy the moment|
|Schweinsteiger: Germany have big-match experience|
|Vidal relaxed over future|
|Bartomeu drooling over Barca strikeforce|
|Gerrard should remain captain, says Beckham|
|Cafu throws support behind Scolari|
|Sabella warns Argentina|
|MLS Review: Henry, Defoe star, as late goals rain down|
|Klinsmann: Germany are favourites|
|Robben rejects Van Gaal´s United proposal|
|Blind hopes Dutch youngsters stick together|
|Thiago Silva frustrated by failure|
|Adrian leaves Atletico for Porto|
|Van Gaal proud after Dutch win|
|Scolari leaving future up to CBF|
|Mixed emotions for Robben|
|FIFA World Cup: Brazil 0 Netherlands 3|
|Sabella remains unsure of Di Maria fitness|
|Abdennour pleased with friendly workout|
|Halilhodzic to take charge at Trabzonspor|
|Fenerbahce delighted to finally sign Diego|
|Low and Germany ready for finale|
|Lyon agree Rose deal|
|Neymar´s World Cup delights Bartomeu|
|De Laurentiis: Higuain going nowhere|
|Beckham lauds ´amazing´ Messi|
|PSG beat Videoton in seven-goal thriller|
|Horta makes Malaga switch|
|Southampton seal deal for Pelle|
|Barcelona ´convinced´ of reduction in Suarez ban|
|West Ham held by League Two Stevenage|
|Bianchi makes move to England|
|West Ham must be more clinical, says Allardyce|
|Germany experience will count - Lehmann|
|Berahino and Dorrans strike in Albion win|
|Ince settling quickly at Hull|
|Swansea in talks with Napoli over Michu|
|Dodo eyes Champions League with Inter|
|FIFA World Cup Preview: Germany v Argentina|
|Huddlestone out to hit the ground running|
|Pogba not bound for Chelsea - agent|
|Barry feeling fresh with Everton|
|Arteta plays down transfer talk|
|PSV complete De Jong deal|
|Colback excited for busy pre-season|
|Milan and Orlando in talks over Robinho|
|West Brom bring in Pocognoli|
|Maradona: Messi will define World Cup final|
|Rami seals Milan move|
|Kuyt eager to secure third place|
|Rodriguez talks up Real Madrid move|
|Bebe welcomes Benfica link|
|Koeman admits unsettled Lovren could leave|
|FIFA World Cup Final Preview: Argentina face old foes Germany with Brazil´s party in tatters|
|FIFA World Cup Final Preview: Messi aims to cement legacy|
|FIFA World Cup Final Preview: Sabella on the brink of greatness|
|FIFA World Cup Final Preview: Muller seeks to augment outstanding finals record|
|FIFA World Cup Final Preview: Low´s hard work pays off|
|FIFA World Cup Final Preview: The coaches to have tasted glory|
|FIFA World Cup Final Preview: The five most iconic finals|
|FIFA World Cup Final Preview: The five most iconic finals|
|FIFA World Cup Final Preview: Germany´s route to the final|
|FIFA World Cup Final Preview: Brazil 2014 produces moments to remember|
|SJ Earthquakes 1 DC United 2: Johnson, Silva score as Eastern Conference leaders extend advantage|
|Otamendi unfazed by price tag|
|Sam targeting top three with Schalke|
|Rodriguez out for revenge|
|Bruno Alves could leave Fenerbahce|
|Thiago Silva endured sleepless nights|
|Final on enemy soil ´special´, says Zabaleta|
|Arteta: Sanchez signing highlights Arsenal´s ambition|
|Mertesacker demands repeat performance|
|Scolari gets federation backing|
|Balotelli poses with shotgun|
|Lizarazu lauds Argentina´s craftiness|