Inter will aim to extend their seven-game unbeaten run when they host second-tier Trapani in the Coppa Italia's fourth round on Wednesday.
Inter – who have not won a trophy since claiming the Coppa Italia in 2011 – entered the competition in the third round after last year's disappointing Serie A finish.
With the top eight sides last season's Serie A not coming into the competition until the fifth round, Inter's placing of ninth saw them at the risk of a shock loss in the early stages.
But they saw off Cittadella 4-0 in August, as Rodrigo Palacio scored a double in their comfortable win, and they enter their match against Trapani on the back of a good run.
Walter Mazzarri's side have lost just once this season – that being to the second-placed Roma – and sit fourth in the Serie A table.
They were not at their best on Sunday though, drawing 1-1 with Sampdoria at San Siro in a performance that Mazzarri claimed was their poorest of the season.
Inter's injury list is lengthy at the moment, with Diego Milito, Mauro Icardi, Cristian Chivu, Yuto Nagatomo and Walter Samuel all sidelined.
But they still should have far too much about them for Trapani, who lie 13th in Serie B.
Trapani – who were champions of the third tier last season – have taken time to find form in the current campaign but will be buoyed by three successive victories.
The latest of those came on Saturday as Simone Basso's 68th-minute strike gave them a 1-0 triumph over Virtus Lanciano.
Inter are one of eight Serie A sides remaining in the fourth round, with six of them at home.
In the two all top-flight ties, high-flying Verona travel to strugglers Sampdoria on Thursday, while Atalanta take on Sassuolo a day earlier.
Frosinone are the lowest-ranked side still remaining in the competition, sitting fourth in Lega Pro I.
The third-tier outfit are on the road to Avellino on Tuesday, after suffering their first defeat in more than two months on Saturday. Avellino are also in good form and are fourth in the Serie B table.
Other fixtures on Tuesday see Parma host Varese, Bologna take on Siena and Spezia battle Pescara, while on Wednesday, Chievo battle Reggina.
|Wenger criticism baffles Redknapp|
|Leicester must strengthen in window - Walsh|
|United not title contenders - Docherty|
|Koeman: Southampton youngsters will get a chance|
|Dyche empathises with Liverpool striker crisis|
|Cagliari turn to Zola|
|Rooney thanks Van Gaal for Christmas break|
|Cruzeiro offer Paulinho Tottenham exit chance|
|Carlisle´s wife grateful to Burnley|
|Katebe called up to Zambia AFCON squad|
|Cape Verde name AFCON squad|
|Finke names much-changed Cameroon squad|
|Grant omits World Cup troublemakers for AFCON|
|Blackpool striker Ranger goes AWOL|
|Allardyce relishing Mourinho meeting|
|Ashley fails to increase Rangers stake|
|Crystal Palace v Southampton: Koeman calls for focus|
|Warnock targeting striker in January|
|Chelsea v West Ham: Adrian vows visitors will attack|
|Heskey signs short-term deal at Bolton|
|Everton v Stoke City: Martinez eyes strong form|
|Juninho defends David Luiz|
|Burnley v Liverpool: Dyche defends Rodgers ahead of Turf Moor test|
|Arsenal v QPR: Wenger eyes festive momentum|
|Liverpool are growing in confidence, says Rodgers|
|Redknapp: Austin future could depend on survival|
|Martinez wants Everton consistency|
|Barca want Neymar until 2020, says agent|
|Jones undeterred by pressure of Liverpool starting role|
|Allardyce ´knows how to beat managers´ - Carroll|
|Jones playing for a new contract|
|China select Evergrande spine for Asian Cup|
|A-League Preview: Koren tips City to build|
|Khedira keen to fight for Real spot|
|Southampton confirm Elia deal|
|Cellino to remain as Leeds owner until after appeal|
|Manchester United v Newcastle United: Van Gaal demands domination|
|Van Gaal refuses to dismiss Bale speculation|
|Sunderland v Hull City: Bruce sure of Hull revival|
|Swansea City v Aston Villa: Lambert optimistic of away success|
|Agbonlahor red rescinded|
|Falcao depends on team-mates to perform - Van Gaal|
|Monk dismisses talk of Gomis move|
|West Brom v Manchester City: Pellegrini to experiment again|
|Xavi: I was ready for New York switch|
|Ibrahimovic fumes at awards snub|
|Irvine: No approaches for Berahino|
|Pearson determined to revive Leicester fortunes|
|League Two Preview: First host third as Wycombe meet Luton|
|League One Preview: Buoyant MK Dons eye more glory, Bristol City seek response|
|Championship Preview: Pritchard plotting to end Ipswich run, Bournemouth host Fulham|
|Kaboul place not guaranteed by captaincy - Pochettino|
|Koeman hopeful of Elia deal|
|Atletico president not ruling out Torres return|
|Swansea secure Oliveira signing|
|No excuses for Pellegrini|
|Walcott pace unaffected by injury|
|Former Real Madrid star Roberto Carlos backs Ronaldo for Ballon d´Or|
|Former PFA chairman Carlisle ´stable´ after serious incident|
|Balotelli remorse saved him from longer ban|
|Bayern midfielder Martinez ´on track´ with rehab|
|Pardew ´overjoyed´ at Gutierrez return|
|Spurs confirm Yedlin to join in January|
|Zeman sacked by Cagliari|
|Casillas: I´m going nowhere|
|Bruce demands McShane apology|
|Pulis would welcome Brighton talks|
|Buffon: Juve angry after Supercoppa loss|
|Arteta out until new year|
|Rangnick: Kampl deserves Dortmund switch|
|PFA offers support to Carlisle after serious incident|
|Napoli can mount title bid - Higuain|
|Cech´s agent urges Liverpool and Arsenal to make bid|
|Hart happy to be back to his best|
|Terry thrilled with ´revelation´ Matic|
|Perez rues ´unfair´ Tyne-Wear derby result|
|Khalfan Ibrahim returns from injury|
|Magath slams ´sensitive´ Fulham|
|´Limited´ attacking options inspire Postecoglou´s selections|
|Carlisle reportedly involved in serious incident|
|Primeira Liga Review: Braga leapfrog Guimaraes|
|Hughes upbeat despite Stoke defeat|