Champions Juventus open the new Serie A season with a trip to one of only the three grounds they lost at in 2012-13.
Antonio Conte's side face Sampdoria at Stadio Luigi Ferraris - where they were beaten 3-2 on the final day of last season - on Saturday.
Juventus have made significant additions to their squad ahead of the new term, with Carlos Tevez and Fernando Llorente the stand-out names.
Both players will be hoping to open their accounts for their new club on the first day, while Manolo Gabbiadini is set to make his Sampdoria debut against his former side.
Napoli have also had a productive close-season as they attempt to close the gap on Juventus, having finished second in Serie A in 2012-13.
Rafael Benitez has replaced Walter Mazzarri in the hot-seat and he will have a host of new names available for Sunday's visit of Bologna.
Star striker Edinson Cavani may have left, but Benitez has added Pepe Reina, Gonzalo Higuain, Dries Mertens, Jose Maria Callejon and Raul Albiol to his squad.
However, they will have to be careful against a Bologna side that won twice at the Sao Paolo last season, scoring three goals on both occasions in the league and the Italian Cup.
Mazzarri left Naples to join Inter and he begins his tenure at San Siro at home to Genoa on Sunday.
Inter had a poor campaign under Andrea Stramaccioni last term, and the new coach is expected to make wholesale changes in order to make sure the club once again challenges at the top of the table.
Genoa have not beaten Inter since 1994, although they did pick up draws in both games last season.
Serie A new boys Verona, Livorno and Sassuolo all face tough trips on the opening weekend of the season.
Verona welcome Milan side off the back of Masimiliano Allegri's side's 1-1 draw with PSV in the UEFA Champions League play-off round on Tuesday.
New Roma coach Rudi Garcia takes charge of his first game in their visit to Livorno. The Frenchman has made 13 new signings in the close-season, including highly-rated Dutch midfielder Kevin Strootman.
Sassuolo's first Serie A game in their 91-year history sees them travel to face Torino.
Head coach Eusebio Di Francesco guided the club to the Serie B title by three points last year, and he will be hoping they can cause an upset against a Torino side who struggled in the top flight last season.
Elsewhere, Cagliari face Atalanta, Lazio and Udinese go head-to-head at Stadio Olimpico and Vincenzo Montella's Fiorentina - who have signed the likes of Joaquin and Mario Gomez in the close-season - host Catania.
|1||Angelo Da Costa|
|29||L. De Silvestri|
|Coach: D. Rossi|
for M. Eramo 72'
for D. Gastaldello 72'
for G. Berardi 83'
|Primeira Liga: Academica 1 Braga 1|
|La Liga: Getafe 3 Granada 3|
|Ligue 1: Reims 1 Marseille 1|
|Scottish Premiership: Kilmarnock 0 Celtic 3|
|Bundesliga: Augsburg 1 Schalke 2|
|Eredivisie: Cambuur 3 RKC Waalwijk 2|
|Ligue 1 Preview: Paris Saint-Germain v Saint-Etienne|
|West Brom blast ´unprofessional´ Anelka, deny he has left|
|Serie A Preview: Genoa v Juventus|
|Verratti in contention for Saint-Etienne clash|
|Davies appeals second touchline ban|
|Anelka terminates West Brom contract|
|Guardiola expresses support for jailed Hoeness|
|Premier League Preview: Manchester United v Liverpool|
|Premier League Preview: Tottenham v Arsenal|
|Menez unsure over PSG future|
|Bendtner will be fined, says Wenger|
|La Liga Preview: Barcelona v Osasuna|
|Liverpool welcome back Lucas, Sakho|
|Moyes welcomes Van Persie commitment|
|Ranieri expects Abidal return|
|Hughes confirms Huth setback|
|Lambert lauds Villa trio|
|Real ´miss´ Arbeloa, says Ancelotti|
|Palacio pens new Inter deal|
|Millwall swoop for Maierhofer|
|Aguero a doubt for Manchester derby|
|Poyet relieved to focus on relegation scrap|
|Fabregas: I will not replace unique Xavi|
|Lennon confident of Commons talks|
|Hainer named chairman of Bayern supervisory board|
|Pochettino eyeing home comforts against Norwich|
|Palace suffer Chamakh blow|
|De Sanctis expresses sorrow for Strootman|
|Mourinho expresses fears over Chelsea squad depth|
|A-League: Sydney 1 Brisbane Roar 1|
|Diouf out for ´several months´|
|Palace have work to do in relegation battle, claims Pulis|
|Cerezo: Atletico can collect silverware|
|Kick It Out call for stronger sanctions|
|Chelsea can handle the pressure, claims Cech|
|Ozil set for four-week absence|
|Valero salutes ´fantastic´ Fiorentina|
|Hoeness resigns Bayern presidency|
|Monk unmoved by Koeman talk|
|Buffon ´regrets´ Juve lapse|
|Toure dismisses talk of City failure|
|Mel prepared to prove a point|
|Copa Libertadores Wrap: Atletico Paranaense claim key win|
|Colombia Primera A Wrap: Alianza Petrolera climb off the bottom|
|Copa do Brasil Wrap: Coritiba held|
|Chelsea, City favourites for title, says Sturridge|
|Liga del Futbol Profesional Boliviano: Tight battle at the top|
|Montella hails attacking Fiorentina|
|K-League Preview: Tricky trip for Jeonbuk|
|Sherwood: Benfica boss ´lacked class´|
|Conte optimistic about Euro chances|
|Sabella: Romero is my number one|
|Van Persie wants United stay|
|UEFA Europa League: Tottenham 1 Benfica 3|
|UEFA Europa League: Juventus 1 Fiorentina 1|
|UEFA Europa League: Sevilla 0 Real Betis 2|
|UEFA Europa League: AZ 1 Anzhi 0|
|UEFA Europa League: Lyon 4 Viktoria Plzen 1|
|Castro bemoans disallowed goal|
|Ronaldo has helped me greatly, says Bale|
|The best team won, concedes Reina|
|FA defend handling of Anelka ´quenelle´ case|
|UEFA Europa League: Ludogorets 0 Valencia 3|
|UEFA Europa League: Porto 1 Napoli 0|
|UEFA Europa League: Basel 0 Red Bull Salzburg 0|
|Mulumbu: We need four or five wins to stay up|
|Premier League Preview: Aston Villa v Chelsea|
|La Liga Preview: Malaga v Real Madrid|
|Premier League Preview: Swansea City v West Brom|
|FA opt not to appeal Anelka ban|
|Premier League Preview: Stoke City v West Ham|
|Bundesliga Preview: Bayern Munich v Bayer Leverkusen|
|Benteke urges cup-final approach|
|Premier League Preview: Everton v Cardiff City|
|Premier League Preview: Southampton v Norwich City|
|Premier League Preview: Fulham v Newcastle United|
|Hughton ´disappointed´ to be only black manager|
|Lewandowski close to Dortmund comeback|
|Bellamy claims improvement under Solskjaer|
|Unbeaten run is not a priority - Alaba|
|Remy, Debuchy face injury lay-offs|
|Genoa can upset Juventus, says Antonelli|
|Every game a cup final, says Zaccardo|
|Pardew ´relieved´ not to lose job|
|League One Preview: Slade ready for Brentford test, Wolves face Shrewsbury|
|La Liga Preview: Atletico Madrid v Espanyol|
|Serie A Preview: Milan v Parma|
|Bundesliga Preview: Borussia Dortmund v Borussia Monchengladbach|
|Premier League Preview: Hull City v Manchester City|
|Serie A Preview: Bottom four go head-to-head, Chievo meet slumping Fiorentina|
|CSL Preview: Shenxin face second derby, Evergrande host Harbin|
|Serie A Preview: Verona v Inter|
|Championship Preview: Millwall face rivals Charlton, play-off battle intensifies|
|Gardner, Brown set for Sunderland returns|
|Gardner, Brown set for Sunderland returns|
|Premier League Preview: Sunderland v Crystal Palace|
|League Two Preview: York eye play-off push, Rochdale ready for derby|
|Allardyce aiming to pick up quick points|
|Gunter signs contract extension at Freiburg|
|Busquets: Title will be decided at Bernabeu|
|Hoeness receives three-and-a-half-year sentence|
|Ramsey out of Tottenham clash|
|Guarin focusing on future at Inter|
|Koeman interested in Swansea role, says agent|
|Stevens expecting more from Stuttgart|
|Agger: Liverpool can handle title pressure|
|Netherlands fall to lowest FIFA ranking in over a decade|
|Adler confident Hamburg can survive ´brutal´ season|
|Champions League still achievable for Everton, says Martinez|
|Zabaleta slams ´shocking´ decisions|
|Blanc: Europe starting to take note of PSG|
|Messi targets silverware|
|Sherwood hopes outburst will reinvigorate Tottenham|
|Martino: Barca must ride momentum|
|Liga MX Preview: Cruz Azul seek form reversal, Toluca in tow|
|Costa Rica Primera Division Wrap: Herediano stumble sends Deportivo Saprissa top|
|CONCACAF Champions League Wrap: Joy for MLS clubs|
|Copa Libertadores Wrap: Nacional Asuncion rise late, Botafogo beaten|
|J.League Preview: Kashima Antlers, Sagan Tosu in top-two tussle|
|Rooney wants United armband|
|Cousillas waves away Aguero fears|
|Messi: Barca progress never in doubt|