Tim Matavz's second-half strike secured a 1-1 draw for PSV as their UEFA Champions League play-off with Milan hangs in the balance.
Stephan El Shaarawy opened the scoring for the visitors after 15 minutes with a close-range header at the end of a flowing move.
Kevin-Prince Boateng released Ignazio Abate down the right-hand side and his pin-point cross was met by the striker, who headed powerfully past Jeroen Zoet.
PSV got themselves level on the hour as Matavz reacted quickest to head past Christian Abbiati after the goalkeeper had failed to hold a Jeffrey Bruma strike.
And despite late pressure, neither side could find a winner to give them the advantage heading into the second leg.
After being cup-tied for last season’s European campaign, Mario Balotelli was given his first start for Milan in the Champions League. He was partnered in attack by El Shaarawy and Boateng.
PSV coach Philip Cocu was dealt a blow in the lead-up to the game with the news that in-form striker Zakaria Bakkali had been ruled out with a groin injury.
The 17-year-old – who has scored four goals in four games in all competitions this season – was replaced in the starting line-up by Matavz.
PSV started well, but having survived an early period of pressure Milan sprang into life in the 15th minute as El Shaarawy broke the deadlock.
The 20-year-old rose unmarked to head home Abate’s right-wing cross after some lax PSV defending.
The Dutch side sought a response, and with eight minutes of the half to play Adam Maher came close to levelling, only to see his shot rattle the crossbar.
The 20-year-old midfielder broke at pace towards the Milan defence before holding off the challenge from Cristian Zapata and firing in his shot, only for the woodwork to come to Abbiati's rescue.
Milan should have doubled their lead early in the second half but El Shaarawy missed two clear-cut chances after excellent work from Balotelli.
The striker saw his first chance bounce wide of Zoet after a delicate chip, and his second opportunity was denied by a perfectly timed tackle from Jetro Willems.
Those misses proved to be costly as PSV equalised on the hour mark.
Bruma sent a speculative long-range effort towards goal and the ball bounced in front of Abbiati, causing it to strike him on the chest and loop into the air.
And before the goalkeeper could react, Matavz pounced to head the ball into the back of the net to put the Eredivisie side level.
On-loan defender Karim Rekik had a fantastic opportunity to win the game for PSV late on, but he mistimed his header following a perfect Georginio Wijnaldum cross.
|Coach: P. Cocu|
for Ji-Sung Park 69'
for T. Matavž 76'
for S. Schaars 89'
|Mourinho explains Fosu-Mensah snub|
|Klopp: No more unwanted players at Liverpool|
|Inter want more than €60m for Icardi - Thohir|
|Leicester can replace Kante - Ranieri|
|Lazio complete Wallace signing|
|Gueye set to join Everton, confirms Di Matteo|
|Tuchel: Transfer market has gone cash crazy|
|Leicester hand King new four-year deal|
|No deal done for Pogba, says Raiola|
|Rooney: Mourinho impact already huge|
|Lafferty hit with FA betting charge|
|Top-four finish never enough for Arsenal, insists Wenger|
|Partey hoping to make his mark on Atletico squad|
|Ibrahimovic in, Schweinsteiger out as United head for Galatasaray friendly|
|Vietto set for Sevilla after completing medical|
|I rejected Besiktas to fight for Barcelona spot, reveals Mathieu|
|De Laurentiis fumes at Higuain´s ´lack of respect´|
|Promising Janssen boosts Tottenham´s title hopes|
|Besiktas sign Adriano on three-year contract|
|Tottenham 0 Atletico Madrid 1: Godin grabs the winner|
|Gomis completes Marseille loan move|
|Iniesta surprised at Casillas-Del Bosque spat|
|New Juve signings do not guarantee success - Allegri|
|New Juve signings do not guarantee success - Allegri|
|Middlesbrough snap up goalkeeper Guzan|
|Guardiola still loves Ribery despite jibes|
|West Ham worry over Tore injury|
|Serie A could be another one-horse race, says Eriksson|
|Schweinsteiger retires from Germany duty|
|Iniesta welcomes Barca´s midfield competition|
|Drogba: No luck in Arsenal scoring record|
|Wenger seeks ´experienced´ striker to bolster Arsenal attack|
|Eriksson and Shanghai SIPG still fighting|
|MLS All-Stars 1 Arsenal 2: Premier League giants win late as Xhaka makes debut|
|Conte: I want aggression and intensity|
|Wimmer backs physical Janssen for Tottenham success|
|Klopp: I wouldn´t spend £100m on one player|
|Sampaoli: Taking Argentina job would be irresponsible|
|Payet absence no excuse - Noble|
|Gabriel Jesus expects Palmeiras exit amid Manchester City rumours|
|Domzale 2 West Ham 1: Crnic double stuns Bilic´s side|
|Juventus target Gabriel Barbosa says Santos exit is close|
|Leicester duo ready for ´once in a lifetime´ Champions League journey|
|Fabregas apologises for Klavan lunge|
|Reschke: Guardiola wanted Tuchel to be his successor|
|Pochettino expecting further Tottenham signings|
|Given retires from international football|
|Abdi and Pudil swap Watford for Wednesday|
|Leicester sign Chilwell to new five-year deal|
|Klopp pre-season ´most intense ever´ for Sturridge|
|Simeone backs Griezmann for Ballon d´Or final three|
|Puskas Award winner quits football - to become a gamer|
|Simeone: Champions League final felt like a death|
|Higuain: I have to prove my worth to Juventus|
|Guardiola confirms interest in Sane and Stones|
|Moreno set for Manchester City switch and Deportivo loan, claims agent|
|De Laurentiis pushed me into Juventus move - Higuain|
|Savic seeking to put injury woe behind him|
|Borussia Dortmund 1 Manchester City 1 (5-6 pens): Gunn´s shootout saves earn Guardiola first win|
|Oblak: Atleti need consistency and luck|
|Warburton rubbishes Van Persie rumours|
|Hospitalised Grujic ´can´t remember anything´, says Klopp|
|Premier League, Serie A appeal to Simeone|
|Copa Libertadores success ´a dream´ for Borja|
|Pochettino honoured by Simeone comparisons|
|Argentina have not asked for Sampaoli - Monchi|
|Ancelotti: Fitness the key for Bayern|
|Bayern win ´a small foundation´ for Montella´s Milan|
|Icardi missing due to injury - Mancini|
|Emery satisfied with warm-up win over Madrid|
|Conte quiet on Tevez, apologises for Fabregas red|
|´It was far from a friendly´ - Klopp on Chelsea defeat|
|Madrid off the pace, concedes Zidane|
|Chelsea 1 Liverpool 0: Cahill´s header seals win|
|Grujic says Chelsea´s Matic told him to sign for Liverpool|
|Bolasie wants to see Berahino and Benteke at Crystal Palace|
|Rodgers hails ´outstanding result´ as Celtic draw|
|Walcott claims level of MLS is close to Premier League|
|Bayern Munich 3 AC Milan 3 (3-5 on penalties): Bonaventura seals win|
|Atletico Nacional 1 Independiente del Valle 0 (2-1 agg): Borja secures Copa Libertadores crown|
|Icardi absent again as Inter held by Estudiantes|
|Real Madrid 1 Paris Saint-Germain 3: Zidane oversees poor pre-season start|
|Hazard vows to rediscover best Chelsea form|
|Klopp reveals why he sent Sakho back to Liverpool|
|Tevez: Conte wanted me at Chelsea|
|Sunderland hopeful Defoe will be fit for Man City opener|
|Sundowns overcome Zamalek to book semi-final spot|
|Falcao scores as Monaco return ends in defeat to Fenerbahce|
|Southampton overcome Twente, Asoro stars for Sunderland|
|Man City must adapt to Guardiola tactics quickly - Denayer|
|Chelsea and Leicester to play in EFL Trophy as five Premier League clubs refuse|
|Tolisso pulls plug on €37.5m Napoli move to stay at Lyon|
|Ancelotti shrugging off Guardiola´s shadow|
|Uruguay international Lodeiro swaps Boca for Seattle|
|Ibrahimovic will bring United back to where they belong - Larsson|
|Transfer speculation frustrates Aubameyang|
|Willian ready for ´toughest Premier League season in history´|
|Astana 1 Celtic 1: Griffiths hits late equaliser|
|De Laurentiis feels betrayed by Higuain swapping Napoli for Juventus|
|Costa: Chelsea cannot be any worse than last season|
|Wilshere: Xhaka can hold Arsenal midfield together|
|Pato signs four-year deal with Villarreal|
|Higuain sets sights on Champions League after Juventus move|
|Lazio snap up Immobile from Sevilla|
|Batshuayi worth the money, insists Cahill|
|Arnautovic signs new Stoke deal|
|Smith leaves Liverpool for Bournemouth|
|Barcelona insist Arda Turan will stay|
|Andre Gomes: Barcelona suit my identity better than Real Madrid|
|Niersbach to appeal FIFA ban|
|Barcelona agree Mascherano renewal|
|Fernandinho can play in 10 positions - Guardiola|
|Reading´s kit launch is out of this world|
|Ben Arfa: I do not want to be PSG´s star player|
|FA Cup to trial fourth substitute|
|We want Balotelli and he wants us, says Besiktas chief|
|Crowd welcomes Higuain as he arrives for Juventus medical|
|Guardiola warns Man City stars: If you´re not fit, danger is coming|
|Mkhitaryan prepares to prove himself at United|
|Cavani: No pressure replacing Ibrahimovic|
|Wenger vows to keep transfer plans ´secret´ after Lacazette snub|
|Brannagan open to Championship loan move|
|Wenger wants to sign Mertesacker replacement|
|Ancelotti: Bayern´s transfer business done|
|Brisbane Roar sign former Danish international Kristensen|
|Verratti, Luiz missing for PSG|
|Sounders part ways with foundation coach Schmid|
|Mane turned down Manchester United for Liverpool|
|Zidane on Pogba: Until August 31, anything can happen|
|Mkhitaryan driven by father´s death|
|Inter rejected Napoli offer for Icardi, says president|
|Clichy: City fighting fit after Guardiola pizza ban|
|Everton and Burnley win as Hull are held|
|Ajax held by PAOK after Cillessen howler|
|Conte left frustrated by ´crazy´ money in transfer market|