Wayne Rooney's possible inclusion will intrigue many as England face Scotland for the first time in almost 14 years at Wembley on Wednesday.
The fixture is the oldest in the history of international football and will be used by manager Roy Hodgson to evaluate his options ahead of crucial FIFA World Cup qualifiers in September.
England will be expected to beat Moldova at Wembley on September 6, but face a testing trip to Ukraine four days later, which will go a long way to deciding who qualifies from UEFA Group H.
Wayne Rooney’s inclusion in the hosts' squad has caused controversy, with the Manchester United man having featured for just 45 minutes of his club's pre-season campaign.
The 27-year-old was sent home from United's tour of Asia due to a hamstring injury, and then suffered a knock to his shoulder in his first appearance – in a behind-closed-doors outing against Real Betis.
However, Hodgson has insisted that Rooney is fit to play, hitting back at claims from Old Trafford boss David Moyes that featuring in the game would only serve to show how unfit the striker is.
If Rooney proves to be ultimately unfit, he may replaced by the squad's debutant – Southampton striker Rickie Lambert.
The 31-year-old netted 15 times in his maiden Premier League season last term, bettered by not one of his countrymen in the top flight and equalled only by Frank Lamaprd.
Whoever England opt to go with, they will not have an easy run against Scotland, who have looked promising under new manager Gordon Strachan, who took the reins in January.
Scotland have won two of the former midfielder's four games in charge, including a superb 1-0 win in their last outing away to Croatia.
The defeat represented just the second time that Croatia had lost a competitive match on home soil – the only other side to have matched Scotland's feat is England.
Strachan could hand international bows to Brighton and Hove Albion defender Gordon Greer and Dundee United attacker Gary Mackay-Steven.
But Scotland are still without the key trio of Darren Fletcher, Gary Caldwell and Steven Fletcher, who remained sidelined through illness and injury.
|T. Walcott||29' 58'|
|Coach: R. Hodgson|
for J. Wilshere 46'
for S. Gerrard 62'
for T. Cleverley 68'
for W. Rooney 68'
for T. Walcott 75'
for P. Jagielka 84'
|Lusitans v West Ham: Tomkins seeks to silence minnows|
|Kagawa shines as Dortmund hit six in Japan|
|Alonso tips Gerrard for Galaxy glory|
|Firmino seeks self-improvement with Liverpool|
|Buffon bids farewell to Pirlo|
|Sterling named Europe´s ´most valuable´ young player|
|Casillas´ agent reveals Porto offer|
|Southampton bring in Martina|
|Dundee United accept Celtic´s Ciftci bid|
|McArthur pens new Palace deal|
|Bartomeu rules out Barca move for Pogba this year|
|Spurs have to be better now - Bentaleb|
|Milner expects central role|
|Micronesia thrashed again, this time 46-0|
|Marchisio: I cannot be Pirlo´s heir|
|Inter aiming for Champions League return - Icardi|
|UEFA Europa League Preview: Brondby and Slovan to protect handsome leads|
|Bentaleb pens new long-term deal at Tottenham|
|Barca agree Turan deal|
|FIFA bans Mayne-Nicholls|
|United States v Honduras: Klinsmann demands improvement ahead of Gold Cup opener|
|CONCACAF institutes extensive reforms in wake of FIFA corruption scandal|
|Mauri completes Milan move|
|City sign Turkey striker|
|Women´s World Cup final draws huge US TV ratings|
|My first Chelsea team better than current crop - Drogba|
|Bertrand set for lay-off after knee surgery|
|New five-year Juve deal for Marchisio|
|Allegri extends Juve contract|
|Koeman reiterates Alderweireld interest|
|Valencia bag Bakkali|
|New York City FC complete Pirlo capture|
|Panama v Haiti: Collat ready to challenge the best of CONCACAF|
|UEFA Champions League Preview: Harrison eyes TNS progression|
|FIFA sanctions Yemen for fielding ineligible player|
|Toulouse rubbish Ben Yedder exit reports|
|Mourinho ´knows what he´s doing´ with Falcao signing|
|Watford shell out club-record fee for Capoue|
|Braafheid signs Lazio extension|
|Nani finalises Fenerbahce move|
|Liverpool confirm O´Driscoll appointment|
|Liverpool have to start better - Lucas|
|USA simply too good - Sasaki|
|Portland Timbers 1 San Jose Earthquakes 0: Jewsbury wins it in stoppage time|
|No move yet for Van Persie|
|Lloyd wins Golden Ball, Silver Boot awards|
|Mascherano: I never grabbed Banega|
|Dunga requested Brazil not appeal Neymar´s suspension|
|United States 5 Japan 2: Lloyd stars with hat-trick|
|Fiorentina deny Inter criticism|
|Nani relishing Fenerbahce opportunity|
|Newcastle hold talks over Northampton youngster|
|Cuadrado´s agent plays down Chelsea exit rumours|
|Liverpool´s Alberto set for Deportivo loan|
|Leverkusen suffer surprise defeat, Stuttgart hit six|
|Inter ´dismayed´ at Fiorentina vice-president´s Salah Twitter outburst|
|Blaszczykowski ruled out of Dortmund´s Asia tour|
|Gerrard gets the beers in for LA Galaxy fans|
|De Gea coy over Real links|
|Former Brazil star Carlos handed Delhi reins|
|Ciftci will not push through Celtic switch – agent|
|In-demand Mitrovic considering Roma offer|
|Lehmann calls on Cech to ´get over´ Chelsea|
|Marlos double sinks Monaco|
|Mauritius 0 South Africa 2 (agg 0-5): Bafana set up Angola qualifier|
|Keane relishing Gerrard arrival|
|Palace confirm Cabaye interest|
|Hamburg bring in Spahic after head-butt ban|
|Blatter hits out at France and Germany over World Cup votes|
|Sanchez: World Cup exit spurred Chile to Copa glory|
|Jojic makes Cologne switch, Santana move falls through|
|Carrillo keen to get going at Monaco|
|Micronesia thrashed 38-0 as Fiji triumph in Olympic qualifier|
|Schalke stunned by ´machine´ Caicara|
|MLS Review: Keane shines at Gerrard´s Galaxy unveiling|
|Counter-attacking the key for Japan|
|Jimenez happy at Atletico|
|Gerrard predicts ´successful future´ with Galaxy|
|Iniesta can´t see Real selling Ramos|
|Keshi sacked as Nigeria coach|
|Three finals, three defeats for Messi, Mascherano|
|Nani close to Fenerbahce move|
|Sampaoli revels in ´unbelievable joy´|
|Bravo: Copa victory a dream|
|Martino: Argentina should have won|
|Chile 0 Argentina 0 (4-1 on penalties): Hosts end trophy drought|
|Germany 0 England 1 (after extra time): England make World Cup history|