UEFA Europa League debutants Astra Giurgiu and Pandurii Targu Jiu both sealed their place in the play-off round on Thursday.
Romania's Astra came into their home clash with Trencin holding a 3-1 lead, and managed to retain that advantage to run out 5-3 aggregate victors despite a crazy final 10 minutes that saw four goals.
The Slovakian visitors netted in the 83rd minute through Fanendo Adi before Astra's Mirko Ivanovski equalised in the 86th, and the pattern was repeated when Gino van Kessel netted just 60 seconds prior to Fwayo Tembo as the game ended 2-2.
Pandurii's meeting with Hapoel Tel-Aviv was arguably less chaotic, though they needed to come from a goal behind as Eric Pereira and Alexandru Ciucur struck to hand them a 2-1 victory on the night and a 3-2 aggregate success.
And Kukesi, the lowest ranked team in the competition, ensured Thursday would indeed be the day of the underdog in the Europa League, as their 1-0 defeat to Metalurh Donetsk in Ukraine saw them through 2-1 on aggregate.
The Albanian outfit ominously conceded with just 27 minutes on the clock, but held out even after Enco Malindi was red-carded with over quarter of an hour remaining.
That trio will join a host of illustrious names in the play-off round after they also sealed their passage on Thursday.
Saint-Etienne were among them, earning a 6-0 aggregate win with a 3-0 victory over Milsami away from home, while Swansea City needed only a 0-0 draw against Malmo to take a 4-0 success overall.
Elsewhere, braces for Coke and Raul Rusescu helped Sevilla win 6-1 at Mladost Podgorica - 9-1 on aggregate - as Standard Liege completed a 4-2 win over Xanthi by inflicting a 2-1 defeat on the night.
Udinese beat Siroki Brijeg 4-0 and 7-1 on aggregate and Club Brugge's 3-3 draw with Slask Wroclaw saw them leave the competition courtesy of a 4-3 overall defeat.
Penalties were required to separate the teams in two of the ties.
Tromso ran out 4-3 victors on spot-kicks after suffering a 1-0 defeat to Differdange that levelled the tie, but St Johnstone's fairytale run was ended against Minsk in the same fashion as they went down 3-2 following another 1-0 loss.
In other matches, Rubin Kazan, Dila Gori, Maccabi Haifa and Qarabag completed routine aggregate victories by taking second-leg success against Randers, Hajduk Split, Ventspils and Gefle respectively.
Bursaspor, Slovan Liberec, Thun and Jablonec also saw out their ties in comfortable fashion, beating Vojvodina, Zurich, Hacken and Stromsgodset.
Motherwell and Crvena Zvezda were not as fortunate, as they both saw penatlies saved before going out at the hands of Kuban Krasnodar and Chornomorets Odesa respectively.
Thursday also saw a flurry of red cards, with Hapoel Ramat Gan losing a man as they were defeated by Estoril and 10-man Zilina going out after drawing 1-1 with Rijeka.
Lech Poznan and Zaligiris went one better in Poland, though, with both teams having a player sent off as two goals in the last three minutes failed to help the hosts avoid a defeat on away goals.
Over in the Netherlands, Vitesse Arnhem suffered arguably the cruellest exit of the round, as a 95th-minute free-kick handed Petrolul a 2-1 win on the night and a 3-2 overall victory.
But there was joy for Trabzonspor, Stuttgart and Rapid Wien, who saw off Dinamo Minsk, Botev Plovdiv and Asteras to progress.
And, in the final match of the day, Aktobe of Kazakhstan defeated Iceland's Breidablik 2-1 on penalties, after the latter had won the second leg 1-0 to level the tie at 1-1.
The first five penalty-takers failed to hit the target before Emil Kenzhisariev and Timur Kapadze slotted their spot-kicks for Aktobe, either side of Nichlas Rohde's converted effort for Breidablik.
Andrey Sidelnikov made the decisive save for the Kazakhstani visitors, stopping Rene Troost's penalty to send Aktobe into the play-offs.
|5||S. Ben Youssef|
|22||M. Ivanovski||44' 86'|
|Coach: D. Isăilă|
for C. Budescu 63'
for William 75'
for T. Seto 90'
|Ligue 1 Review: Paris Saint-Germain and Lyon make Marseille pay for slip-up|
|Burkina Faso coach puts AFCON exit down to bad luck|
|Saint-Etienne 0 Paris Saint-Germain 1: Ibrahimovic scores in repeat performance|
|Shenaishil optimistic despite Kasim absence|
|Walcott: Goal has been a long time coming|
|DR Congo v Tunisia: Leekens warns against complacency|
|Congo 2 Burkina Faso 1: Thievy helps send 2013 runners-up crashing out|
|Gabon 0 Equatorial Guinea 2: Balboa and Iban put hosts through|
|McCarthy and Distin on road to recovery|
|Gil has hit the ground running - Lambert|
|Eredivisie Review: Ajax and Feyenoord lose ground after dour draw, Eagles secure big win|
|Wenger confirms Gabriel move is imminent|
|Eto´o presented to Sampdoria fans|
|Cape Verde v Zambia: Victory a must for 2012 winners to avoid elimination|
|Brighton and Hove Albion 2 Arsenal 3: Walcott and Ozil among the goals for holders|
|Mancini upbeat despite ´cruel´ late defeat|
|Pogba revelling in rich vein of form|
|Aston Villa 2 Bournemouth 1: Gil helps under-fire Lambert breathe easy|
|Defour dismissed after Standard Liege banner taunt|
|Allardyce relieved with scrappy West Ham win|
|Sturridge ´happy man´ after return to Liverpool training|
|Inter 0 Torino 1: Moretti ends unbeaten run for top-four hopefuls|
|Juventus 2 Chievo 0: Pogba inspires victory as leaders march on|
|Bristol City 0 West Ham 1: Super sub Sakho sinks City|
|Hughes in talks over new Stoke deal|
|Delph signs new contract|
|Chelsea v Liverpool: Mourinho demands League Cup response|
|Football League Preview: Derby eye top two, Cambridge back to reality|
|Nani not giving up on Old Trafford career|
|Perth Glory 3 Melbourne Victory 3: Leaders stage two-goal late comeback|
|Neymar: Barca have no interest in Real results|
|Milan defender Mexes apologises for red card|
|South Korea v Iraq: Strange lead-up for Shenaishil´s men|
|Lazio´s Djordjevic thanks well-wishers ahead of ankle surgery|
|Iran´s Asian Cup appeal dismissed by AFC|
|Cech urges Chelsea to clean up FA Cup exit ´mess´|
|Henderson: Liverpool are up for the cup|
|Edimar wants ´normal´ ban for Real star Ronaldo|
|Pellegrini defends misfiring City strikers|
|Australia ready for UAE - Sainsbury|
|Blanc takes positives from past|
|Inzaghi promises ´something different´ at Milan|
|Mexes sorry for seeing red|
|La Liga Review: Wins for top three|
|Vitoria Guimaraes 2 Gil Vicente 2: Last-gasp penalty salvages point for hosts|
|Simeone marvels at Griezmann impact|
|Djordjevic to have x-ray on ankle problem|
|Eredivisie Review: PSV go seven points clear, Heerenveen cruise|
|Luis Enrique backs himself on Suarez omission|
|Lazio 3 Milan 1: Parolo and Klose seal victory|
|Cameroon 1 Guinea 1: Draw ensures Group D stays finely poised|
|Rodgers reveals Sturridge fitness boost after Bolton stalemate|
|Atletico Madrid 3 Rayo Vallecano 1: Griezmann inspires routine win|
|Gabriel move agreed, Campbell to join Villarreal on loan|
|Gabon v Equatorial Guinea: Neighbours face off for quarter-final berth|
|FA Cup Review: Chelsea stunned by Bradford as Middlesbrough beat Manchester City|
|Ronaldo apologises for red card|
|Pulis eyes room for improvement|
|Liverpool 0 Bolton Wanderers 0: Championship side frustrate Anfield to earn replay|
|Karanka hails players after stunning City|
|Elche 0 Barcelona 6: Neymar and Messi inspire resounding win|
|League Two Review: Wycombe and Burton held, Shrewsbury up to second|
|Pardew lauds Palace performance|
|Pochettino laments late collapse|
|Scottish Premiership Review: Celtic stretch lead, Inverness and Dundee United keep up chase|
|Parkinson revels in huge upset after humbling Chelsea|
|Bayern targeting unbeaten Bundesliga season - Robben|
|Pearson: FA Cup win can breed confidence|
|League One Review: Dons close gap, Peterborough end run|
|Ivory Coast 1 Mali 1: Gradel rescues Renard´s men|
|Fulham seal Richards loan|
|Pellegrini: UAE trip had no impact|
|Koeman blames defeats on defensive lapses|
|Gundogan injury mars Dortmund preparations|
|Championship Review: Ighalo stars as Blackpool capitulate|
|Chelsea defeat a ´disgrace´ - Mourinho|
|Monk rues missed opportunity|
|Manchester City 0 Middlesbrough 2: Boro stun City with FA Cup shock|
|Chelsea 2 Bradford City 4: League One outfit dump out Premier League leaders|
|Tottenham 1 Leicester City 2: Late turnaround stuns Spurs|
|Cordoba 1 Real Madrid 2: Bale steals late win as Ronaldo sees red|
|Birmingham City 1 West Brom 2: Anichebe seals derby triumph|
|Southampton 2 Crystal Palace 3: Pardew´s men reach fifth round|
|Sunderland 0 Fulham 0: Defoe fails to fire on home debut|
|Bowyer hails ´terrific´ Blackburn|
|Rochdale v Stoke City: Shawcross in race to be fit for cup clash|
|Blackburn Rovers 3 Swansea City 1: Late goals snatch victory for Championship side|
|Congo v Burkina Faso: Le Roy vows to attack|
|Roma still in race for Scudetto - Garcia|
|Mancini coy on Toure links|
|Mertens rules out Napoli exit|
|Barzagli back in Juve squad|
|A-League Review: Adelaide and Sydney rack up the goals|
|Real have signed a ´diamond´ in Silva, says Oliveira|
|Queiroz: How can Williams sleep at night?|
|Asian Cup history ´the focus´ for Australia - Kruse|
|Pogba could be the world´s ´most expensive´ player|
|Australia international joins Dundee United|
|Real Madrid is a ´dream come true´ - Silva|
|Van Gaal angered by first-half showing in cup stalemate|