Real Madrid vs. Barcelona

Thierry Henry and Lionel Messi both netted braces while Carles Puyol and Gerard Pique were also on the score sheet as Pep Guardiola's treble-chasers inflicted a first league defeat on in-form Madrid since beating the reigning champions at the Nou Camp in December.

Madrid had picked up fifty-two points from a possible fifty-four since that match, but their hopes of a third successive title now look sunk after they fell seven points adrift of Barcelona with only four games remaining.

Barcelona, who also hold the better head-to-head record against their rivals, can now clinch the title next weekend if they beat Villarreal and Madrid lose to Valencia.